anti-Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) Antikörper

PITPNM1 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005. Zusätzlich bieten wir Ihnen Phosphatidylinositol Transfer Protein, Membrane-Associated 1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PITPNM1 18739 O35954
PITPNM1 9600 O00562
PITPNM1 361694 Q5U2N3
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Top anti-Phosphatidylinositol Transfer Protein, Membrane-Associated 1 Antikörper auf antikoerper-online.de

Showing 10 out of 91 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-PITPNM1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: Human heart WB Suggested Anti-PITPNM1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Human heart 100 μL 2 bis 3 Tage
$289.00
Details
Maus Ziege Unkonjugiert ELISA, ICC, WB   100 μg 6 bis 7 Tage
$429.84
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Rind (Kuh) Ziege Unkonjugiert IF, WB   0.1 mg 6 bis 8 Tage
$445.50
Details
Human Kaninchen Unkonjugiert WB Western blot analysis in ZR-75-1 cell line lysates (35ug/lane). Western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane). 400 μL 2 bis 3 Tage
$515.63
Details
Rind (Kuh) Ziege Unkonjugiert ELISA, WB   100 μg 11 bis 14 Tage
$610.50
Details
Human Maus Unkonjugiert WB Western Blot analysis of PITPNM1 expression in transfected 293T cell line by PITPNM1 MaxPab polyclonal antibody.Lane 1: PITPNM1 transfected lysate(136.73 KDa).Lane 2: Non-transfected lysate. 50 μL 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μg 11 bis 14 Tage
$419.83
Details
Maus Ziege APC ELISA   100 μL 16 Days
$760.57
Details
Maus Ziege Alkaline Phosphatase (AP) ELISA   100 μL 16 Days
$760.57
Details

Am meisten referenzierte anti-Phosphatidylinositol Transfer Protein, Membrane-Associated 1 Antikörper

  1. Human Polyclonal PITPNM1 Primary Antibody für WB - ABIN4892952 : Aryal, Rao: Deficiency in Cardiolipin Reduces Doxorubicin-Induced Oxidative Stress and Mitochondrial Damage in Human B-Lymphocytes. in PLoS ONE 2016 (PubMed)
    Show all 2 Pubmed References

  2. Mouse (Murine) Polyclonal PITPNM1 Primary Antibody für ELISA - ABIN250210 : Lev, Hernandez, Martinez, Chen, Plowman, Schlessinger: Identification of a novel family of targets of PYK2 related to Drosophila retinal degeneration B (rdgB) protein. in Molecular and cellular biology 1999 (PubMed)

Weitere Antikörper gegen Phosphatidylinositol Transfer Protein, Membrane-Associated 1 Interaktionspartner

Mouse (Murine) Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) Interaktionspartner

  1. Pitpnm1 null mice showed no hearing defects.

  2. results suggest that Nir2 not only enhances EMT in vitro and breast cancer metastasis in animal models, but also contributes to breast cancer progression in human patients.

  3. RdgB homologs play a preemptive role in excluding endogenous and exogenous modified purine deoxyribonucleoside triphosphates (dTNPs) from incorporation into DNA.

Human Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) Interaktionspartner

  1. results suggest that Nir2 not only enhances EMT in vitro and breast cancer metastasis in animal models, but also contributes to breast cancer progression in human patients.

  2. Phosphatidic acid production triggers Phosphatidylinositol 4,5-Bisphosphate replenishment mediated by Nir2 and Nir3 at endoplasmic reticulum-plasma membrane junctions.

  3. Nir2 translocates from the Golgi complex to the plasma membrane in response to GF stimulation.

  4. Results suggest a feedback mechanism that replenishes PM PIP2 during receptor-induced Ca(2+) signaling via the Ca(2+) effector E-Syt1 and the PITP Nir2 at ER-PM junctions.

  5. Nir2, a human homolog of Drosophila melanogaster retinal degeneration B protein, is essential for cytokinesis.

  6. A specific Thr residue in the Nir2 PI-transfer domain provides a regulatory site for targeting to lipid droplets. This may affect intracellular lipid trafficking & distribution & explain the dominant effect of the RdgB-T59E mutant on retinal degeneration.

  7. Phosphorylation of Nir2 by Cdk1 facilitates its dissociation from the Golgi apparatus, and phospho-Nir2 is localized in the cleavage furrow and midbody during cytokinesis.

  8. Nir2 is involved in maintaining a critical DAG pool in the Golgi apparatus by regulating its consumption via the CDP-choline pathway

  9. RdgB homologs play a preemptive role in excluding endogenous and exogenous modified purine deoxyribonucleoside triphosphates (dTNPs) from incorporation into DNA.

Phosphatidylinositol Transfer Protein, Membrane-Associated 1 (PITPNM1) Antigen-Profil

Protein Überblick

PITPNM1 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005

Genbezeichner und Symbole assoziert mit PITPNM1

  • phosphatidylinositol transfer protein membrane associated 1 (PITPNM1) Antikörper
  • phosphatidylinositol transfer protein, membrane-associated 1 (Pitpnm1) Antikörper
  • DRES9 Antikörper
  • Mpt-1 Antikörper
  • Nir-2 Antikörper
  • NIR2 Antikörper
  • PITPNM Antikörper
  • PITPnm 1 Antikörper
  • R75447 Antikörper
  • Rd9 Antikörper
  • RDGB Antikörper
  • RDGB1 Antikörper
  • RDGBA Antikörper
  • RDGBA1 Antikörper

Bezeichner auf Proteinebene für PITPNM1

phosphatidylinositol transfer protein, membrane-associated 1 , phosphatidylinositol transfer protein, membrane-associated 1-like , membrane-associated phosphatidylinositol transfer protein 1-like , drosophila retinal degeneration B homolog 1 , membrane-associated phosphatidylinositol transfer protein 1 , pyk2 N-terminal domain-interacting receptor 2 , retinal degeneration 9 , NIR-2 , PITPnm 1 , PYK2 N-terminal domain-interacting receptor 2 , drosophila retinal degeneration B homolog , retinal degeneration B alpha 1 , phosphatidylinositol membrane-associated

GENE ID SPEZIES
533859 Bos taurus
610462 Canis lupus familiaris
721716 Macaca mulatta
769912 Gallus gallus
100408084 Callithrix jacchus
100465754 Ailuropoda melanoleuca
100547262 Meleagris gallopavo
100586982 Nomascus leucogenys
100607998 Pan troglodytes
18739 Mus musculus
9600 Homo sapiens
361694 Rattus norvegicus
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