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Binds to heparin. Zusätzlich bieten wir Ihnen POSTN Antikörper (192) und POSTN Kits (70) und viele weitere Produktgruppen zu diesem Protein an.
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the occurrence of periostin in the healthy adult human tooth without co-localization with proteins involved in tooth mineralization, the expression of which it regulates
Periostin is down-regulated in ankylosing spongylitis patients with highly active disease and may contribute to disease pathogenesis through an interaction with Wnt (zeige WNT2 Proteine) signaling.
Our study demonstrates differences in Periostin (PN) expression in histological subtypes of Papillary Thyroid Carcinoma. Our results plead in favor of a dominant protumorigenic role of stromal PN, while the action of epithelial PN is less noticeable
POSTN may function as a protective factor for osteoblasts during this process by inhibiting the eIF2alphaATF4 pathway.
Circulating levels of DLL1 (zeige DLL1 Proteine) and POSN were higher in patients with severe dilated cardiomyopathy and correlated with the degree of diastolic dysfunction.
High concentrations of serum periostin in acute ICH (zeige COL4a2 Proteine) patients are associated with increasing severity and a poor functional prognosis
These results demonstrate that POSTN promotes the osteogenic differentiation of mesenchymal stem cells (MSCs) and that CTLA4 (zeige CTLA4 Proteine) enhances the ectopic osteogenesis of MSCs-CTLA4 (zeige CTLA4 Proteine)-based tissue-engineered bone.
measurement of a periostin fragment resulting from in vivo cathepsin K (zeige CTSK Proteine) digestion may help to identify subjects at high risk of fracture.
Study shows that POSTN is present at high levels in ovarian cancer (OC) ascetic fluids, correlates with CD163 (zeige CD163 Proteine)+ tumor-associated macrophages and, inversely associates with relapse-free survival for OC patients. Overall, data indicate that POSTN is an important factor for macrophage recruitment in the tumor microenvironment and is involved in the interactions between macrophages and ovarian cancer cells.
confirm associations between periostin and markers of type 2 inflammation, as well as lung function, and identify novel constitutional factors of importance to the use of periostin as a phenotype-specific biomarker in asthma.
Unaffected by Postn, Vav (zeige VAV1 Proteine)-Itgav (zeige ITGAV Proteine)(-/-) haematopoietic stem cell proliferate faster in vitro, illustrating the importance of Postn-Itgav (zeige ITGAV Proteine) interaction.
Periostin-expressing myofibroblasts in the heart derive from tissue-resident fibroblasts of the Tcf21 (zeige TCF21 Proteine) lineage and are necessary for adaptive healing and fibrosis.
Results indicate that periostin is a key player in the development of bleomycin-induced fibrosis and consequent enhancement of tumor cell colonization in the lung.
Periostin gene deletion impairs periosteal cells functions and fracture consolidation.
these data indicate that CatK (zeige CTSK Proteine) not only plays a major role in bone remodeling but also modulates modeling-based cortical bone formation by degrading periostin and thereby moderating Wnt (zeige WNT2 Proteine)-beta-catenin (zeige CTNNB1 Proteine) signaling.
Ablation of periostin suppresses post-infarction myocardial regeneration by inhibiting the PI3K/GSK3beta/cyclin D1 (zeige CCND1 Proteine) signalling pathway, indicating that periostin is essential for myocardial regeneration.
this study shows that periostin regulates fibrocyte function to promote myofibroblast differentiation and lung fibrosis
Genetic or pharmaco-genetic inhibition of periostin in animal models of renal disease was efficient in arresting the progression of the kidney pathology. (Review)
TGFBI (zeige TGFB1 Proteine) and periostin act similarly in the heart in affecting fibrosis and disease responsiveness.
Results suggest that stromal cell periostin (POSTN) supports both normal hematopoietic progenitor cells (HPCs) and leukemia-initiating cells in vitro.
These results suggest that periostin is one of the local contributing factors in bone and periodontal tissue remodeling following mechanical stress during experimental tooth movement [periostin].
Binds to heparin. Induces cell attachment and spreading and plays a role in cell adhesion. May play a role in extracellular matrix mineralization.
, periostin, osteoblast specific factor
, extracellular adhestion molecule
, osteoblast-specific factor 2
, osteoblast specific factor 2 (fasciclin I-like)
, periodontal ligament-specific periostin
, periostin isoform thy2
, periostin isoform thy4
, periostin isoform thy6
, periostin isoform thy8
, periostin-like factor
, periostin variant 6
, periostin variant 7
, periostin variant 8
, periostin variant 9