Peptidyl Arginine Deiminase, Type IV Proteine (PADI4)

PADI4 is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. Zusätzlich bieten wir Ihnen PADI4 Antikörper (118) und PADI4 Kits (20) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
PADI4 23569 Q9UM07
PADI4 18602 Q9Z183
PADI4 29512 O88807
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Top PADI4 Proteine auf antikoerper-online.de

Showing 10 out of 14 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$9,797.11
Details
Baculovirus infected Insect Cells Human His tag,GST tag,GST tag 10 μg Anmelden zum Anzeigen 20 bis 21 Tage
$303.60
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Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$522.50
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Baculovirus infected Insect Cells Human His tag SDS-PAGE 50 μg Anmelden zum Anzeigen 20 bis 21 Tage
$547.80
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Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$3,934.33
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Escherichia coli (E. coli) Human T7 tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$672.00
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Insektenzellen Maus GST tag   100 μg Anmelden zum Anzeigen 25 bis 30 Tage
$875.87
Details

PADI4 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, , , ,
Mouse (Murine)
,
Rat (Rattus)

Weitere Proteine zu Peptidyl Arginine Deiminase, Type IV (PADI4) Interaktionspartnern

Human Peptidyl Arginine Deiminase, Type IV (PADI4) Interaktionspartner

  1. PADI4 may be closely associated with hypoxiainduced autophagy, and the inhibition of hypoxiainduced autophagy by PADI4 knockdown may contribute to an increase in the apoptosis of RAFLS.

  2. MiRNA-146a rs2910164 and IRAK1 (zeige IRAK1 Proteine) rs3027898 polymorphisms were a risk factor for predisposition to Rheumatoid Arthritis in Egyptian Population in codominant and dominant tested inheritance models, while, the miRNA-499 rs3746444 and PADI4 rs1748033 polymorphisms were a risk factor in codominant and recessive one.

  3. Meta-analysis indicated a significantly increased association between PADI -104C/T polymorphism and rheumatoid arthritis (RA) in Chinese and Japanese populations (which were the majority of included populations in the analysis).

  4. PADI4 interacted with SYVN1 (zeige SYVN1 Proteine) directly and that overexpression of PADI4 suppressed the ubiquitination of proteins. Thus, a reduction in ER stress induced by PADI4 may abrogate the initiation of chronic RA by suppressing the proliferative signals of RA synoviocytes.

  5. mRNA expression of PADI2 (zeige PADI2 Proteine), PADI4 and Sp1 (zeige PSG1 Proteine) is upregulated in rheumatoid arthritis bone marrow CD34 (zeige CD34 Proteine)+ cells independently of the systemic inflammation or treatment regimen.

  6. this study in a Southern Mexican population suggests that PADI4 individual polymorphisms and the related susceptibility haplotype (GTG (zeige GGT1 Proteine)) are also genetic risk markers for rheumatoid arthritis

  7. The T allele of PADI4 rs2240340 is associated with Rheumatoid Arthritis in Asians.

  8. PADI4 contributes to gastric tumorigenesis by upregulating CXCR2 (zeige CXCR2 Proteine), KRT14 (zeige KRT14 Proteine) and TNF-alpha (zeige TNF Proteine) expression.

  9. In this case-control study with sufficient sample size to detect associations, we observed that PADI4 SNPS rs11203367 and rs874881 do not significantly determine RA susceptibility

  10. SNPs of PADI4 may be a risk factor for airway abnormalities in RA.

Mouse (Murine) Peptidyl Arginine Deiminase, Type IV (PADI4) Interaktionspartner

  1. PADi4 is critical for neutrophil extracellular traps formation, but is dispensable for generalized citrullination

  2. sFlt-1 overexpression in Padi4(-/-) mice resulted in dramatically lower inflammatory and thrombotic response, which was accompanied by significant reduction in pregnancy losses. Inhibition of NETosis may serve as a novel target in disorders of impaired placentation.

  3. a role for NETs in cardiac fibrosis and conclude that PAD4 regulates age-related organ fibrosis and dysfunction.

  4. PADI4 exacerbates arthritis with diverse immunological modifications.

  5. Selective inhibition of peptidylarginine deiminase IV with Cl-amidine blocked NET formation, reduced atherosclerotic lesion area, and delayed time to carotid artery thrombosis in a photochemical injury model.

  6. Padi4 is part of the pluripotency transcriptional network, binding to regulatory elements of key stem-cell genes and activating their expression

  7. PAD4 regulates the proliferation of multipotent progenitors in the bone marrow by controlling c-myc (zeige MYC Proteine) expression.

  8. PAD4-mediated chromatin decondensation in the neutrophil is crucial for pathological venous thrombosis and present neutrophil activation and PAD4 as potential drug targets for deep vein thrombosis.

  9. PAD4 is dispensable in this effector phase model of arthritis

  10. analysis of regulation of histone modification and chromatin structure by the p53 (zeige TP53 Proteine)-PADI4 pathway

PADI4 Protein Überblick

Protein Überblick

This gene is a member of a gene family which encodes enzymes responsible for the conversion of arginine residues to citrulline residues. This gene may play a role in granulocyte and macrophage development leading to inflammation and immune response.

Genbezeichner und Symbole assoziert mit PADI4

  • peptidyl arginine deiminase 4 (PADI4)
  • peptidyl arginine deiminase, type IV (Padi4)
  • peptidyl arginine deiminase 4 (Padi4)
  • PAD Protein
  • Pad4 Protein
  • PADI5 Protein
  • Pdi4 Protein
  • PDI5 Protein

Bezeichner auf Proteinebene für PADI4

peptidyl arginine deiminase, type IV , protein-arginine deiminase type-4-like , HL-60 PAD , PADI-H protein , peptidyl arginine deiminase, type V , protein-arginine deiminase type IV , protein-arginine deiminase type-4 , PAD type IV , peptidylarginine deiminase IV , PAD-R4 , peptidyl arginine deiminase, type 4 , peptidylarginine deiminase type alpha

GENE ID SPEZIES
100026011 Monodelphis domestica
100049826 Equus caballus
100415489 Callithrix jacchus
100471129 Ailuropoda melanoleuca
100592291 Nomascus leucogenys
23569 Homo sapiens
18602 Mus musculus
456530 Pan troglodytes
29512 Rattus norvegicus
606921 Canis lupus familiaris
508161 Bos taurus
100524749 Sus scrofa
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