PAD4 Protein (AA 1-663) (His tag,Biotin)

Produktnummer ABIN7275398

Produktdetails

Target: PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))

Protein-Typ: Recombinant

Proteineigenschaft: AA 1-663

Spezies: Cynomolgus

Quelle: Escherichia coli (E. coli)

Aufreinigungstag / Konjugat: Dieses PAD4 Protein ist gelabelt mit His tag,Biotin.

Verwendungszweck: Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling)

Sequenz: Met1-Pro663

Produktmerkmale: Recombinant Biotinylated Cynomolgus PADI4 Protein (Primary Amine Labeling) is expressed from E.coli with His tag at the N-Terminus.It contains Met1-Pro663.

Reinheit: > 95 % as determined by Tris-Bis PAGE

Sterilität: 0.22 μm filtered

Endotoxin-Niveau: Less than 1EU per μg by the LAL method.

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Supplied as 0.22μm filtered solution in 20 mM Tris, 500 mM NaCl, 10 % Glycerol, 0.5 mM TCEP, 1 mM EDTA ( pH 8.0).

Konservierungsmittel: Other preservative

Lagerung: -80 °C

Informationen zur Lagerung: Valid for 12 months from date of receipt when stored at -80°C.,Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Haltbarkeit: 12 months

Antigendetails

Target: PAD4 (PADI4) (Peptidyl Arginine Deiminase, Type IV (PADI4))

Andere Bezeichnung: PADI4 (PADI4 Produkte)

Hintergrund: Peptidylarginine deiminase type4 (PADI4) was firstly identified as a non-MHC RA genetic risk factor. Furthermore, PADI4 risk allele possessed the association with bone damage regardless of anti citrullinated peptide antibody (ACPA) positivity in Asian RA patients. PADI4 gene codes PAD4 protein which has post-translational modification activity (citrullination). Padi4 is mainly expressed in myeloid cells and granulocytes.

Molekulargewicht: 76.6 kDa same as Tris-Bis PAGE result.

UniProt: A0A2K5USI5