Pepsinogen C Proteine (PGC)

PGC encodes an aspartic proteinase that belongs to the peptidase family A1. Zusätzlich bieten wir Ihnen PGC Antikörper (176) und PGC Kits (69) und viele weitere Produktgruppen zu diesem Protein an.

Gen	GeneID	UniProt
PGC	5225	P20142
PGC	109820	Q9D7R7
PGC	24864	P04073

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Showing 10 out of 27 products:

Katalog Nr.	Origin	Quelle	Konjugat	Menge	Anbieter	Lieferzeit	Preis	Details
ABIN3085950	Insektenzellen	Human	His tag	1 mg	Anmelden zum Anzeigen	50 Days	$6,749.58	Details
ABIN3129252	Insektenzellen	Maus	His tag	1 mg	Anmelden zum Anzeigen	50 Days	$6,749.58	Details
ABIN2005019	Human Cells	Human	His tag	10 μg	Anmelden zum Anzeigen	14 bis 16 Tage	$250.80	Details
ABIN2009149	Human Cells	Ratte	His tag	10 μg	Anmelden zum Anzeigen	14 bis 16 Tage	$250.80	Details
ABIN6387837	Baculovirus infected Insect Cells	Human	His tag	100 μg	Anmelden zum Anzeigen	13 bis 16 Tage	$1,230.77	Details
ABIN1080481	Escherichia coli (E. coli)	Human	His tag	100 μg	Anmelden zum Anzeigen	15 bis 18 Tage	$448.00	Details
ABIN4974206	Escherichia coli (E. coli)	Human	His tag	50 μg	Anmelden zum Anzeigen	11 Days	$341.00	Details
ABIN4974207	Hefe	Human	His tag	50 μg	Anmelden zum Anzeigen	8 bis 11 Tage	$341.00	Details
ABIN1314794	Wheat germ	Human	GST tag	10 μg	Anmelden zum Anzeigen	11 bis 12 Tage	$414.29	Details
ABIN1080480	Escherichia coli (E. coli)	Ratte	His tag	100 μg	Anmelden zum Anzeigen	15 bis 18 Tage	$720.00	Details

PGC Proteine nach Spezies und Herkunft

Origin	Exprimiert in	Konjugat
Human	, , , , , , , ,	, ,
Mouse (Murine)	,	,
Rat (Rattus)	, ,

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Weitere Proteine zu Pepsinogen C (PGC) Interaktionspartnern

Human Pepsinogen C (PGC) Interaktionspartner

Recombinant pepsin C and pepsinogen C were purified from transgenic rice culture medium, and the NH2-terminal 5-residue sequences were verified by amino acid sequencing.
serum levels correlated with age, sex and the level of Helicobacter pylori infection
Pepsinogen-II 100 bp ins/del gene polymorphism and its elevated circulating levels are associated with gastric cancer, particularly with Helicobacter pylori infection and intestinal metaplasia.
Results suggest that rs9471643 CG and rs6458238 AG/AA genotypes have important roles in up-regulating PGC expression, which may partially explain why individuals with these favorable genotypes have decreased risks of getting gastric cancer.
Data show that SNP interactions among H. pylori-related genes PGC, PTPN11, and IL1B, are associated with susceptibility to gastric carcinogenesis.
Serum pepsinogens I (PGI) and II (PGII), gastrin 17 (G-17), and antibodies against whole H. pylori, or cytotoxin-associated gene A (CagA) antigen among 309 consecutive patients, were measured.
The results highlight an important role of PGC rs3789210 and rs6939861 in altering susceptibility to atrophic gastritis and/or gastric cancer.
Pepsinogen II is a good marker of corpus morphological changes before and after H. pylori eradication.
High serum Pepsinogen II level is associ9ated with the progression of gastric precancerous lesions.
An interaction effect of pri-let-7a-1 rs10739971 polymorphism with ERCC6 rs1917799 polymorphism was observed for the risk of gastric cancer.
Pepsin and pepsinogen in middle ear effusion are probably caused by LPR and may be involved in the pathogenesis of OME.
plasma PG II level significantly correlated with H. pylori-infected gastric cancer
High serum pepsinogen II is associated with gastric cancer development and activity of Helicobacter pylori-associated chronic gastritis.
Levels of pepsinogen/pepsin A and C are higher in the mouth swabs of infants with clinical gastroesophageal reflux.
PGC rs6458238, PGC rs4711690 and PTPN11 rs12229892 were associated with susceptibilities to atrophic gastritis and/or gastric cancer.
Data suggest that serum pepsinogen I/II ratio (pepsinogen A/C ratio) is correlated with diabetic nephropathy and thus may be a biological marker for degree of urinary albumin excretion in patients with type 2 diabetes.
The serum levels of PG II and G-17 were significantly higher in Changle than those in Fuan.
Data suggest that subjects with higher PGI level, and PG I/II ratio are more likely to develop several dyspeptic symptoms.
Chinese patients with sPGII greater than 10.25 microg/L are at greater risk of various H. pylori-related gastropathies.

PGC Protein Überblick

Protein Überblick

This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.

Genbezeichner und Symbole assoziert mit Pepsinogen C Proteine (PGC)

progastricsin (pepsinogen C) (PGC)
progastricsin (PGC)
progastricsin (pepsinogen C) (Pgc)
progastricsin (Pgc)

2210410L06Rik Protein
CPGC Protein
Gastricsin Protein
PEPC Protein
Pg-1 Protein
PG1 Protein
PGC Protein
PGII Protein
PGNC Protein
Upg-1 Protein
Upg1 Protein

Bezeichner auf Proteinebene für Pepsinogen C Proteine (PGC)

gastricsin , pepsinogen C , pepsin C , pepsinogen group II , preprogastricsin , urinary pepsinogen 1 , Urinary pepsinogen 1 , gastricsin-like

GENE ID	SPEZIES
554184	Monodelphis domestica
5225	Homo sapiens
109820	Mus musculus
395690	Gallus gallus
24864	Rattus norvegicus
100009323	Oryctolagus cuniculus
100135598	Cavia porcellus
100404738	Callithrix jacchus

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