PRKC, Apoptosis, WT1, Regulator (PAWR) ELISA Kits

The tumor suppressor WT1 represses and activates transcription. Zusätzlich bieten wir Ihnen PAWR Antikörper (67) und PAWR Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
PAWR 5074 Q96IZ0
PAWR 64513 Q62627
PAWR 114774 Q925B0
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 6.25 pg/mL 25-1600 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
  96 Tests Anmelden zum Anzeigen 2 bis 3 Tage

Weitere ELISA Kits für PAWR Interaktionspartner

Human PRKC, Apoptosis, WT1, Regulator (PAWR) Interaktionspartner

  1. we investigated in the present study the mechanisms regulating the accumulation of a 25kDa (zeige SFRS9 ELISA Kits) cleaved-Par-4 (cl-Par-4) fragment in ovarian and endometrial cancer cell lines

  2. Authors demonstrate that TRIM21 (zeige TRIM21 ELISA Kits) expression predicts survival in pancreatic cancer patients. This work highlights a novel mechanism of Par-4 regulation, and identifies a novel prognostic marker and potential therapeutic target for pancreatic cancer.

  3. Data suggest that PAR4 and P2Y12 (zeige P2RY12 ELISA Kits) heterodimer internalization/endocytosis is required for beta-arrestin-2 (zeige ARRB2 ELISA Kits) recruitment to endosomes and up-regulation of Akt (zeige AKT1 ELISA Kits) signaling; activation of PAR4 but not of P2Y12 (zeige P2RY12 ELISA Kits) drives internalization of the PAR4-P2Y12 (zeige P2RY12 ELISA Kits) heterodimer. (PAR4 = protease-activated receptor 4 (zeige F2RL3 ELISA Kits); P2Y12 (zeige P2RY12 ELISA Kits) = purinergic receptor P2Y (zeige P2RY1 ELISA Kits), G-protein coupled, 12 protein; Akt (zeige AKT1 ELISA Kits) = proto-oncogene (zeige RAB1A ELISA Kits) protein c (zeige PROC ELISA Kits)-akt (zeige AKT1 ELISA Kits))

  4. In this review, we will focus on the therapeutic perspective of Par-4 with a special reference to its (Par-4) virgin prospect of devastating metastasis control.

  5. in vitro and in vivo upregulation of Par-4 expression is indispensable for the trafficking of GRP78 (zeige HSPA5 ELISA Kits) to the cell membrane and subsequent apoptosis of cancer cell

  6. Prostate apoptosis response 4 (PAR4) expression modulates WNT (zeige WNT2 ELISA Kits) signaling pathways in MCF7 breast cancer cells: A possible mechanism underlying PAR4-mediated docetaxel chemosensitivity.

  7. Decreased PAR4 expression in breast cancer is associated with shorter survival. PAR4 suppresses growth and invasiveness of breast cancer cells.

  8. Authors determined that PAR-4 induces cell apoptosis in response to stimuli, in vitro, but is also involved in the relocation of GRP78 (zeige HSPA5 ELISA Kits) from endoplasmic reticulum to the cell surface of ovarian cancer cell line.

  9. These results suggest that Porphyromonas gingivalis activates PAR4 signaling pathways, leading proMMP9 over-expression and cellular invasion in oral squamous cell carcinoma cells.

  10. PAR1 (zeige MARK2 ELISA Kits)-platelet releasate enhances vasculogenesis more potently than PAR4-platelet releasate, and the enhancements require a cooperation of multiple platelet-derived angiogenic regulators.

Mouse (Murine) PRKC, Apoptosis, WT1, Regulator (PAWR) Interaktionspartner

  1. Findings reveal a novel role for Par-4 (zeige F2RL3 ELISA Kits)/NF-kappaB (zeige NFKB1 ELISA Kits) in islet beta cell apoptosis and type 2 diabetes.

  2. Par4 (zeige F2RL3 ELISA Kits), CEBPB (zeige CEBPB ELISA Kits) and FAK (zeige PTK2 ELISA Kits) form a senescence signaling pathway, playing roles in modulating cell survival, growth, apoptosis, EMT (zeige ITK ELISA Kits) and self-renewal

  3. a novel mechanism of apoptosis induction by PAR-4 (zeige F2RL3 ELISA Kits)/ceramide-enriched exosomes, which may critically contribute to Alzheimer disease.

  4. extracellular Par-4 (zeige F2RL3 ELISA Kits)/SAC (zeige ADCY10 ELISA Kits) is systemically functional in inhibition of tumor growth and metastasis progression.

  5. loss of PAR4 (zeige F2RL3 ELISA Kits) leads to a reduction in the ability of tumour necrosis factor-alpha (zeige TNF ELISA Kits) to induce apoptosis by increased activation of NF-kappaB (zeige NFKB1 ELISA Kits)

  6. Antisense knockdown of PAR-4 (zeige F2RL3 ELISA Kits) or inhibition of ceramide biosynthesis reduced stem cell apoptosis; PAR-4 (zeige F2RL3 ELISA Kits) overexpression and treatment with ceramide analogs elevated apoptosis.

  7. AATF (zeige AATF ELISA Kits) is an endogenous antagonist of Par-4 (zeige F2RL3 ELISA Kits) activity and an effective inhibitor of aberrant amyloid beta 1-42 production and secretion under apoptotic conditions.

  8. Par-4 (zeige F2RL3 ELISA Kits) is directly involved in regulating choline uptake by interacting with CHT1 (zeige ChT ELISA Kits) and by reducing its incorporation on the cell surface

  9. the mechanism for Ras-mediated down-regulation of Par-4 (zeige F2RL3 ELISA Kits) is by promoter methylation

  10. direct physical association with ceramide and PAR-4 (zeige F2RL3 ELISA Kits) regulates the activity of PKCzeta (zeige PRKCZ ELISA Kits)

PAWR Antigen-Profil

Beschreibung des Gens

The tumor suppressor WT1 represses and activates transcription. The protein encoded by this gene is a WT1-interacting protein that itself functions as a transcriptional repressor. It contains a putative leucine zipper domain which interacts with the zinc finger DNA binding domain of WT1. This protein is specifically upregulated during apoptosis of prostate cells.

Genbezeichner und Symbole assoziert mit PAWR

  • pro-apoptotic WT1 regulator (PAWR) Antikörper
  • PRKC, apoptosis, WT1, regulator L homeolog (pawr.L) Antikörper
  • PRKC, apoptosis, WT1, regulator (pawr) Antikörper
  • pro-apoptotic WT1 regulator (Pawr) Antikörper
  • PRKC, apoptosis, WT1, regulator (Pawr) Antikörper
  • 2310001G03Rik Antikörper
  • MGC81382 Antikörper
  • Par-4 Antikörper
  • Par4 Antikörper
  • PAWR Antikörper
  • pawrl Antikörper
  • zgc:103513 Antikörper

Bezeichner auf Proteinebene für PAWR

PRKC, apoptosis, WT1, regulator , PAR-4 , PRKC apoptosis WT1 regulator protein , PRKC, apoptosis, WT1, regulator like , WT1-interacting protein , prostate apoptosis response 4 protein , prostate apoptosis response protein 4 , prostate apoptosis response protein PAR-4 , prostate apoptosis response-4 , transcriptional repressor PAR4 , Prostate apoptosis response protein 4 , par-4 induced by effectors of apoptosis , transcriptional repressor Par-4-like protein PAWR

417870 Gallus gallus
447443 Xenopus laevis
449994 Danio rerio
452094 Pan troglodytes
532789 Bos taurus
695617 Macaca mulatta
5074 Homo sapiens
64513 Rattus norvegicus
114774 Mus musculus
611487 Canis lupus familiaris
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