anti-PDZ Binding Kinase (PBK) Antikörper

PBKs encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Zusätzlich bieten wir Ihnen PDZ Binding Kinase Proteine (14) und PDZ Binding Kinase Kits (6) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PBK 55872 Q96KB5
PBK 52033 Q9JJ78
PBK 290326  
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Top anti-PDZ Binding Kinase Antikörper auf antikoerper-online.de

Showing 10 out of 153 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-PBK Antibody Titration: 0.2-1 ug/ml Positive Control: 721_B cell lysate PBK is supported by BioGPS gene expression data to be expressed in 721_B 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- PBK Picoband antibody, IHC(P) IHC(P): Mouse Testis Tissue Anti- PBK Picoband antibody, Western blotting All lanes: Anti PBK at 0.5ug/ml Lane 1: Rat Testis Tissue Lysate at 50ug Lane 2: Mouse Testis Tissue Lysate at 50ug Lane 3: Human Placenta Tissue Lysate at 50ug Lane 4: JURKAT Whole Cell Lysate at 40ug Predicted bind size: 36KD Observed bind size: 36KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of PBK (arrow) using rabbit polyclonal PBK Antibody (C-term C300) (ABIN391245).293 cell lysates (2 µg/lane) either nontransfected (Lane 1) or transiently transfected with the PBK gene (Lane 2) (Origene Technologies). Formalin-fixed and paraffin-embedded human testis tissue reacted with PBK Antibody (C-term C300) (ABIN391245), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Maus Unkonjugiert ELISA, FACS, ICC, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure5: Immunohistochemical analysis of paraffin-embedded colon cancer tissues using PBK mouse mAb with DAB staining. Dilution: 1/200 - 1/1000 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$561.00
Details
Human Maus Unkonjugiert ELISA, FACS, IF/ICC, IHC, WB 100 μL Anmelden zum Anzeigen 11 bis 16 Tage
$426.40
Details
Human Kaninchen Unkonjugiert WB Anti-PBK antibody, All Western blottingAll lanes: Anti-PBK at 0.5ug/ml Lane 1: Rat Testis Tissue Lysate at 40ug Lane 2: HELA Whole Cell Lysate at 40ug Lane 3: MCF-7 Whole Cell Lysate at 40ug Lane 4: SKOV Whole Cell Lysate at 40ug Lane 5: HEPG2 Whole Cell Lysate at 40ug Lane 6: COLO320 Whole Cell Lysate at 40ug Predicted bind size: 36KD Observed bind size: 36KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Western Blot: PBK Antibody [NBP1-84342] - Lane 1: Marker [kDa] 220, 112, 84, 47, 32, 26, 17.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunocytochemistry/Immunofluorescence: PBK Antibody [NBP1-84342] - Staining of mouse medulla shows positivity in a subset of cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IHC, WB   200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$575.00
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from K562 cells treated with UV 30', using PBK/TOPK (Phospho-Thr9) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from COS7 cells, treated with Nocodazole 1ug/ml 16h, using PBK/TOPK (Ab-9) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using PBK/TOPK (Ab-9) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details

Am meisten referenzierte anti-PDZ Binding Kinase Antikörper

  1. Human Monoclonal PBK Primary Antibody für ICC, FACS - ABIN969345 : Oh, Zhu, Cho, Lee, Kang, Kim, Zykova, Bode, Dong: T-lymphokine-activated killer cell-originated protein kinase functions as a positive regulator of c-Jun-NH2-kinase 1 signaling and H-Ras-induced cell transformation. in Cancer research 2007 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal PBK Primary Antibody für WB - ABIN1881635 : Zykova, Zhu, Lu, Higgins, Tatsumi, Abe, Bode, Dong: Lymphokine-activated killer T-cell-originated protein kinase phosphorylation of histone H2AX prevents arsenite-induced apoptosis in RPMI7951 melanoma cells. in Clinical cancer research : an official journal of the American Association for Cancer Research 2006 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal PBK Primary Antibody für ICC, IF - ABIN4343992 : Mulder, Björling, Jonasson, Wernérus, Hober, Hökfelt, Uhlén: Tissue profiling of the mammalian central nervous system using human antibody-based proteomics. in Molecular & cellular proteomics : MCP 2009 (PubMed)

Weitere Antikörper gegen PDZ Binding Kinase Interaktionspartner

Human PDZ Binding Kinase (PBK) Interaktionspartner

  1. Results found that PBK/TOPK was upregulated and phosphorylated in HTLV1-transformed Tcell lines and ATLLderived Tcell lines. In addition, HTLV1 infection upregulated PBK/TOPK expression in PBMCs, suggesting that this kinase increases the rate of mitosis and expands malignant T cells.

  2. Findings strongly suggest that phosphorylated T-lymphokine-activated killer cell-originated protein kinase may be a potent biomarker to determine the outcome of patients with primary central nervous system lymphoma and to develop novel drugs to treat primary central nervous system lymphoma.

  3. the expression of TOPK be a novel alternative biomarker to categorize the malignancy of gliomas.

  4. CDK1 (zeige CDK1 Antikörper)-mediated mitotic phosphorylation of PDZ-binding kinase is involved in cytokinesis and inhibits its oncogenic activity.

  5. Data suggest that T-LAK cell-originated protein kinase (TOPK) might play a pivotal role in breast cancer invasion and metastasis.

  6. our study provide convincing evidences that FoxM1 (zeige FOXM1 Antikörper)-regulated PBK exerts oncogenic activities towards HCC (zeige FAM126A Antikörper) via the activation of beta-Catenin (zeige CTNNB1 Antikörper) pathway.

  7. High TOPK expression is associated with liver cancer.

  8. The role of T-LAK cell-originated protein kinase directly promotes metastasis of colorectal cancer by modulating p53-related protein kinase (zeige TP53RK Antikörper).

  9. TOPK protein and transcriptional levels of FOXM1 (zeige FOXM1 Antikörper) were reduced by TOPK inhibitor treatment.

  10. Results indicate that src (zeige SRC Antikörper)-family kinase (Src (zeige SRC Antikörper)) is a upstream kinase of T-LAK cell-originated protein kinase (TOPK).

Mouse (Murine) PDZ Binding Kinase (PBK) Interaktionspartner

  1. this study shows that remote ischemic postconditioning protects against renal ischemia/reperfusion injury via activation of TOPK/PTEN/Akt (zeige AKT1 Antikörper) signaling pathway

  2. T-LAK cell-originated protein kinase (TOPK) phosphorylation of MKP1 (zeige DUSP1 Antikörper) protein prevents solar ultraviolet light-induced inflammation through inhibition of the p38 protein (zeige RNF19A Antikörper) signaling pathway.

  3. The TOPK protein is expressed mainly in the cytosol of spermatocytes and spermatids, but not in spermatids and spermatogonia in situ.

  4. Melanoma cell lines expressing with high levels of TOPK are more resistant to As(3+)-induced apoptosis. Therefore, inhibition of TOPK activity combined with As(3+) treatment may be helpful in the treatment of melanomas.

PDZ Binding Kinase (PBK) Antigen-Profil

Protein Überblick

This genes encodes a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. This mitotic kinase may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis.

Genbezeichner und Symbole assoziert mit PBK

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  • PDZ binding kinase (Pbk) Antikörper
  • PDZ binding kinase L homeolog (pbk.L) Antikörper
  • 2810434B10Rik Antikörper
  • AW538537 Antikörper
  • CT84 Antikörper
  • D14Ertd732e Antikörper
  • Nori-3 Antikörper
  • PBK Antikörper
  • SPK Antikörper
  • TOPK Antikörper
  • zgc:92050 Antikörper

Bezeichner auf Proteinebene für PBK

PDZ binding kinase , T-LAK cell-originated protein kinase , MAPKK-like protein kinase , cancer/testis antigen 84 , lymphokine-activated killer T-cell-originated protein kinase , serine/threonine protein kinase , spermatogenesis-related protein kinase , PDZ-binding kinase , PBK, PDZ-binding kinase , lymphokine-activated killer T-cell-originated protein kinase homolog

GENE ID SPEZIES
422003 Gallus gallus
464496 Pan troglodytes
496810 Xenopus (Silurana) tropicalis
713242 Macaca mulatta
100341076 Oryctolagus cuniculus
100587879 Nomascus leucogenys
55872 Homo sapiens
52033 Mus musculus
360218 Danio rerio
496340 Xenopus laevis
477371 Canis lupus familiaris
100141310 Sus scrofa
534781 Bos taurus
290326 Rattus norvegicus
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