anti-P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) Antikörper

The protein encoded by PAK7 is a member of the PAK family of Ser/Thr protein kinases. Zusätzlich bieten wir Ihnen PAK7 Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
PAK7 57144 Q9P286
PAK7 241656 Q8C015
PAK7 311450 D4A280
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Top anti-PAK7 Antikörper auf

Showing 10 out of 96 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- PAK5 Picoband antibody, IHC(P) IHC(P): Human Glioma Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of PAK7 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of PAK7 expression in SKNSH (A), K562 (B), COS7 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-PAK5 Pab (ABIN392438) in lysates from transiently transfected COS7 cells. Lane 1: negative control, Lane 2: PAK1-expressing cells, Lane 3: PAK2-expressing cells, Lane 4: PAK4-expressing cells, Lane 5: PAK5-expressing cells, and Lane 6: PAK6-expressing cells. PAK5 (arrow) was detected using purified polyclonal antibody. Data is kindly provided by Drs. Z.M. Jaffer and J. Chernoff from the Fox Chase Cancer Center (Philadelphia, PA). Formalin-fixed and paraffin-embedded human brain tissue reacted with PAK5 antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Kaninchen Unkonjugiert EIA, IP, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
Human Kaninchen Unkonjugiert IHC (p), WB Mouse Pak7 Antibody (N-term) (ABIN657995) western blot analysis in mouse stomach tissue lysates (35 µg/lane). This demonstrates the Pak7 antibody detected the Pak7 protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Kaninchen Unkonjugiert IHC (p) Anti-PAK7 antibody  ABIN1049229 IHC staining of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert ICC, IHC (p), WB Human Brain, Cortex (formalin-fixed, paraffin-embedded) stained with PAK7 antibody ABIN213962 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert IHC (p), ELISA Brain, cortex, Human: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western Blot (WB) analysis of specific cells using PAK5 Polyclonal Antibody. 100 μL Anmelden zum Anzeigen 16 Days
Human Kaninchen Unkonjugiert IF, IHC (p), WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage

PAK7 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-PAK7 Antikörper

  1. Human Polyclonal PAK7 Primary Antibody für ICC, ELISA - ABIN1002958 : Jaffer, Chernoff: p21-activated kinases: three more join the Pak. in The international journal of biochemistry & cell biology 2002 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen PAK7 Interaktionspartner

Human P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) Interaktionspartner

  1. These findings indicate that aberrant PAK7 expression is associated with the occurrence of metastasis and poor clinical outcomes of human colon cancer by promoting the epithelial to mesechymal transition

  2. Data suggest expression of ECAD (E-cadherin (zeige CDH1 Antikörper)) in bladder cancer cell lines correlates with presence of intercellular junctions and level of PAK5 (zeige PAK6 Antikörper) (p21 (zeige CDKN1A Antikörper)-activated kinase PAK5 (zeige PAK6 Antikörper) protein) expression; endogenous PAK5 (zeige PAK6 Antikörper) is localized to intercellular junctions and interacts with ECAD (zeige CDH1 Antikörper); depletion of PAK5 (zeige PAK6 Antikörper) expression reduces integrity of intercellular junctions; PAK5 (zeige PAK6 Antikörper) mRNA levels are reduced in bladder cancer compared with normal controls.

  3. model suggests PAK5 self-association interferes with AID binding to the catalytic domain, thus maintaining its high activity.

  4. PAK7 expression is significantly downregulated in human masticatory mucosa during wound healing

  5. PAK7 is overexpressed in human esophageal squamous cell cancer samples and correlated with lymph node metastasis.

  6. E47 (zeige TCF3 Antikörper) is a novel substrate of PAK5 (zeige PAK6 Antikörper), and PAK5 (zeige PAK6 Antikörper)-mediated phosphorylation of E47 (zeige TCF3 Antikörper) promotes epithelial-mesenchymal transition and metastasis of colon cancer.

  7. Aurora-A induced PAK7 expression in esophageal cancer cells.

  8. results suggest that the inhibition of PAK5 by RNA interference might efficiently suppress tumor development of glioma cells with PAK5 high expression.

  9. miR-129 suppresses tumor cell growth and invasion by targeting PAK5 in hepatocellular carcinoma.

  10. PAK7 promotes cell proliferation and tumorigenesis

Xenopus laevis P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) Interaktionspartner

  1. Xenopus PAK5 regulates convergent extension movements in vivo by modulating the calcium-mediated cell-cell adhesion in blastomeres.

Mouse (Murine) P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7) Interaktionspartner

  1. PAK-7 p21-activated kinase 5 knockout mice are more sensitive to the stimulant effects of amphetamine

  2. functional deficits in PAK5, PAK6 (zeige PAK6 Antikörper) and PAK5/PAK6 (zeige PAK6 Antikörper) knockout mice

  3. PAK 5 is involved in formalin-induced inflammatory nociception through regulation of MAPK-induced c-Fos-activation and formalin-specific transient receptor potential-channels.

  4. These results implicate Pak5 in Pacsin1 (zeige PACSIN1 Antikörper)- and Synaptojanin1-mediated synaptic vesicle trafficking.

  5. PAK5 may provide a molecular rationale for late-stage complications in diabetes.

  6. Our results indicate that Pak5 and Pak6 (zeige PAK6 Antikörper) together are not required for viability, but are required for a normal level of locomotion and activity as well as for learning and memory.

PAK7 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

Genbezeichner und Symbole assoziert mit PAK7

  • p21 (RAC1) activated kinase 5 (PAK5) Antikörper
  • p21 (RAC1) activated kinase 5 L homeolog (pak5.L) Antikörper
  • p21 protein (Cdc42/Rac)-activated kinase 7 (Pak7) Antikörper
  • p21 (RAC1) activated kinase 7 (Pak7) Antikörper
  • 2900083L08Rik Antikörper
  • 6430627N20 Antikörper
  • PAK-5 Antikörper
  • PAK-7 Antikörper
  • Pak5 Antikörper

Bezeichner auf Proteinebene für PAK7

PAK-5 , PAK-7 , p21(CDKN1A)-activated kinase 7 , p21-activated kinase 5 , p21-activated kinase 7 , p21CDKN1A-activated kinase 7 , protein kinase PAK5 , serine/threonine-protein kinase PAK 7 , serine/threonine-protein kinase PAK7 , p21 (CDKN1A)-activated kinase 7

57144 Homo sapiens
398224 Xenopus laevis
241656 Mus musculus
100340742 Oryctolagus cuniculus
311450 Rattus norvegicus
469876 Pan troglodytes
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