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OLIG2 encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. Zusätzlich bieten wir Ihnen OLIG2 Kits (6) und OLIG2 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 121 products:
Human Polyclonal OLIG2 Primary Antibody für ICC, IF - ABIN447418
Kolenda-Roberts, Harris, Singletary, Hardisty: Immunohistochemical characterization of spontaneous and acrylonitrile-induced brain tumors in the rat. in Toxicologic pathology 2012
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Human Monoclonal OLIG2 Primary Antibody für ICC, IHC - ABIN969331
Bonnet-Dupeyron, Combes, Boespflug-Tanguy, Vaurs-Barrière: Absence of OLIG2 mutations in patients presenting with a severe Pelizaeus-Merzbacher-like leukodystrophy associated with motor neuron dysfunction. in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008
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Human Polyclonal OLIG2 Primary Antibody für IHC, IHC (fro) - ABIN447523
Nijland, Michailidou, Witte, Mizee, van der Pol, van Het Hof, Reijerkerk, Pellerin, van der Valk, de Vries, van Horssen: Cellular distribution of glucose and monocarboxylate transporters in human brain white matter and multiple sclerosis lesions. in Glia 2014
Human Monoclonal OLIG2 Primary Antibody für IF, IHC (p) - ABIN523613
Libard, Popova, Amini, Kärjä, Pietiläinen, Hämäläinen, Sundström, Hesselager, Bergqvist, Ekman, Zetterling, Smits, Nilsson, Pfeifer, de Ståhl, Enblad, Ponten, Alafuzoff: Human cytomegalovirus tegument protein pp65 is detected in all intra- and extra-axial brain tumours independent of the tumour type or grade. in PLoS ONE 2014
Dog (Canine) Polyclonal OLIG2 Primary Antibody für IHC, WB - ABIN2777565
Mitkus, Hyde, Vakkalanka, Kolachana, Weinberger, Kleinman, Lipska: Expression of oligodendrocyte-associated genes in dorsolateral prefrontal cortex of patients with schizophrenia. in Schizophrenia research 2007
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Dog (Canine) Polyclonal OLIG2 Primary Antibody für IHC, WB - ABIN2777566
Sun, Hafler, Kaing, Kitada, Ligon, Widlund, Yuk, Stiles, Rowitch: Evidence for motoneuron lineage-specific regulation of Olig2 in the vertebrate neural tube. in Developmental biology 2006
Dog (Canine) Polyclonal OLIG2 Primary Antibody für IHC, WB - ABIN2777314
Cowen, Green: The Kallmann's syndrome variant (KSV) model of the schizophrenias. in Schizophrenia research 1993
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Data suggest positive feedback loops including oligodendrocyte transcription factor 2 (OLIG2): loops of epigenetic regulation.
Data show that oligodendrocyte transcription factor 2 (OLIG2) is epigenetically regulated via DNA methylation (zeige HELLS Antikörper) and expressed in a subset of AML (zeige RUNX1 Antikörper) patients.
Ectopic expression of phosphomimetic Olig2 is sufficient to block TGF-beta2 (zeige TGFB2 Antikörper)-mediated invasion.
phosphorylation of the motif itself serves as a template to prime phosphorylation of additional serines and creates a highly charged "acid blob" in the amino terminus of Olig2.
Olig2 was expressed in cord blood eosinophils on d 24, when cord blood eosinophils are considered fully differentiated, but no earlier. It was also expressed in human peripheral-blood eosinophils but not neutrophils, monocytes, lymphocytes, or cord blood mast cells. Many genes, including eosinophil surface molecules, were up-regulated along with OLIG2. OLIG2 shRNA or siRNA downregulated SIGLEC-8 (zeige SIGLEC8 Antikörper) mRNA and protein.
Data indicate that transcription factors Sox10 (zeige SOX10 Antikörper) and Olig2 play key roles in oligodendrocytes (OLs) specification.
Olig2 expressions were successfully detected in 12 (15.58%) of 77 SVZ type II Glioblastomas (GBs (zeige GNB5 Antikörper)) and 16 (21.3%) of 75 SVZ type III GBs (zeige GNB5 Antikörper).
Olig2 was positive in 5 out of 44 ependymomas (11%) and 50 out of 54 (93%) non-ependymal tumors
The present study is the first to verify the associations of SNPs rs762178, rs1059004, and rs9653711 of the OLIG2 gene with OCD in a Chinese Han population. Thus, OLIG2 might serve as a potential target for OCD treatment
The results demonstrate that the expression of Olig2 in dental pulp stem cells reduces the expression of stem cell markers and induces the development of oligodendrocyte progenitors.
these data raise the possibility that cells expressing olig2 are intermediate targets that help guide facial motor neuron migration.
Study detected at least five different classes of olig2-positive cells in the telencephalon of the adult zebrafish.
By cooperating with Shh (zeige SHH Antikörper), FGF-receptor (zeige FGFR2 Antikörper) signalling controls the expression of olig2, a patterning gene essential for the specification of somatic motoneurons and oligodendrocytes.
Loss of olig2 function prevents primary motor neuron and oligodendrocyte development, whereas olig2 overexpression promotes formation of excess primary motor neurons and oligodendrocytes.
Olig2 is required for repression of iro3 (zeige IRX3 Antikörper) expression in the progenitor domain of ventral spinal cord
data indicate that Hedgehog (zeige SHH Antikörper) & Wnt (zeige WNT2 Antikörper) work in opposition across the dorsoventral axis of the cerebellum to regulate formation of olig2(+) neurons; we propose that Hedgehog (zeige SHH Antikörper) limits the range of Wnt (zeige WNT2 Antikörper) signaling, which is necessary for olig2(+) neuron development
commitment of basal diencephalic DA neurons is regulated by the combined action of the neural protein Olig2 and its downstream neuronal specific effector Sim1
Olig2 is down-regulated in oligodendrocyte progenitor cells infected by Theiler's murine encephalomyelitis virus.
OLIG2 modulates growth factor signaling in two distinct populations of glioma stem cells, characterized by expression of either the epidermal growth factor receptor (EGFR (zeige EGFR Antikörper)) or platelet-derived growth factor receptor alpha (zeige PDGFRA Antikörper).
the dynamic interplay between HMGNs and H1 in chromatin epigenetically regulates the expression of OLIG1 (zeige OLIG1 Antikörper)&2, thereby affecting oligodendrocyte development and myelination, and mouse behavior.
Olig2 was significantly upregulated and transcriptionally targeted the Gpr17 (zeige GPR17 Antikörper) locus
Brg1 (zeige SMARCA4 Antikörper) represses Olig2 expression and the specification of oligodendrocyte progenitors, but is required for OPC differentiation and oligodendrocyte maturation
Data show that oligodendrocyte transcription factor 2 (Olig2) deletion causes platelet-derived growth factor receptor (PDGFR (zeige PDGFRB Antikörper)) downregulation and reciprocal epidermal growth factor receptor (EGFR (zeige EGFR Antikörper)) upregulation.
This study suggests that Olig2 misexpression in neural stem cells elicits neurogenesis defects and neuronal cell death, which may contribute to developmental disorders including Down syndrome
OLIG2 is a multifunctional regulator of neural stem cell self-renewal
Olig2 expression is localized to the cochleovestibular ganglia from E12.5 through E14.5
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14\;21)(q11.2\;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome.
oligodendrocyte transcription factor 4
, oligodendrocyte transcription factor 3
, oligodendrocyte lineage transcription factor 2
, basic domain, helix-loop-helix protein, class B, 1
, class B basic helix-loop-helix protein 1
, class E basic helix-loop-helix protein 19
, human protein kinase C-binding protein RACK17
, oligodendrocyte transcription factor 2
, oligodendrocyte-specific bHLH transcription factor 2
, protein kinase C-binding protein 2
, bHLH transcription factor Olig2