Nuclear ssembly factor 1 ribonucleoprotein Proteine (NAF1)

NAF1 encodes an A20-binding protein which plays a role in autoimmunity and tissue homeostasis through the regulation of nuclear factor kappa-B activation. Zusätzlich bieten wir Ihnen Nuclear ssembly factor 1 ribonucleoprotein Antikörper (4) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
NAF1 234344 Q3UMQ8
NAF1 306387 Q52KK4
NAF1 92345 Q96HR8
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Top Nuclear ssembly factor 1 ribonucleoprotein Proteine auf antikoerper-online.de

Showing 4 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 60 Days
$9,626.73
Details
Hefe Ratte His tag   1 mg 60 bis 71 Tage
$3,285.33
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Hefe Yeast His tag   1 mg 60 bis 71 Tage
$3,393.50
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NAF1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Rat (Rattus)

Human

Weitere Proteine zu Nuclear ssembly factor 1 ribonucleoprotein (NAF1) Interaktionspartnern

Human Nuclear ssembly factor 1 ribonucleoprotein (NAF1) Interaktionspartner

  1. Study presents a novel genome-wide candidate for ductal adenocarcinoma (PDAC) - TERT-rs2736100 and a completely new signal for PDAC in NAF1-rs7675998 that approaches the genome-wide threshold. In addition, study found a strong association between the teloscore and risk of pancreatic cancer, suggesting that telomeres are a potential risk factor for pancreatic cancer.

  2. the current study has identified that rs2320615 in the NAF1 was associated with the risk of esophageal cancer in the Han Chinese population.

  3. These findings point to a key role for the unique 3Cys-1His cluster of NAF-1 in promoting rapid tumor growth through cellular resistance to oxidative stress.

  4. Data indicate that disease in NAF1 mutation carriers is telomere-mediated; they show that NAF1 haploinsufficiency selectively disturbs telomere length homeostasis by decreasing the levels of telomerase RNA while sparing rRNA pseudouridylation.

  5. Telomere length is associated with Esophageal squamous cell carcinoma risk in a U-shaped pattern and demonstrates that TL-SNPs may not be important in carcinogenesis in Chinese population.

Nuclear ssembly factor 1 ribonucleoprotein (NAF1) Protein Überblick

Protein Überblick

RNA-binding protein required for the maturation of box H/ACA snoRNPs complex and ribosome biogenesis. During assembly of the H/ACA snoRNPs complex, it associates with the complex and disappears during maturation of the complex and is replaced by NOLA1/GAR1 to yield mature H/ACA snoRNPs complex. Probably competes with NOLA1/GAR1 for binding with DKC1/NOLA4 (By similarity).

Genbezeichner und Symbole assoziert mit NAF1

  • nuclear assembly factor 1 ribonucleoprotein (Naf1)
  • nuclear assembly factor 1 ribonucleoprotein (NAF1)
  • Gm174 Protein
  • RGD1306802 Protein

Bezeichner auf Proteinebene für NAF1

H/ACA ribonucleoprotein complex non-core subunit NAF1 , nuclear assembly factor 1 homolog

GENE ID SPEZIES
234344 Mus musculus
306387 Rattus norvegicus
92345 Homo sapiens
514182 Bos taurus
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