Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) ELISA Kits

The protein encoded by NEDD9 is a member of the CRK-associated substrates family. Zusätzlich bieten wir Ihnen NEDD9 Antikörper (94) und NEDD9 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
NEDD9 4739 Q14511
Anti-Ratte NEDD9 NEDD9 291044  
NEDD9 18003 O35177
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top NEDD9 ELISA Kits auf antikoerper-online.de

Showing 2 out of 7 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.078 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
€768.05
Details
Maus < 0.059 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
€512.92
Details

Weitere ELISA Kits für NEDD9 Interaktionspartner

Human Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) Interaktionspartner

  1. NEDD9, E-cadherin and gamma-catenin proteins have roles in pancreatic ductal adenocarcinoma

  2. Results reveal the role of a phosphorylation-dependent HEF1-Plk1 complex in HEF1 translocation to FAs to induce cell migration.

  3. Overexpression of NEDD9 promotes cell invasion and metastasis in hepatocellular carcinoma. Also, NEDD9 may serve as potential therapeutic target for the treatment of hepatocellular carcinoma.

  4. MiR-125a-5p may serve as a therapeutic agent for lung adenocarcinoma through its major target, NEDD9.

  5. NEDD9 deregulated Smad7 expression to inhibit Smad signaling and binding to the FAK-Src-Crk complex which is proposed that this is the mechanism by which NEDD9 induced greater sphere formation in cancer stem cells properties.

  6. HIP2 regulates mitotic spindle alignment. SHIP2 is expressed in G1 phase, whereas Aurora A kinase is enriched in mitosis. SHIP2 binds Aurora A kinase and the scaffolding protein HEF1 and promotes their basolateral localization at the expense of their luminal expression connected with cilia resorption.

  7. The protein expression level of NEDD9 is higher in esophageal carcinoma tissues than that in adjacent normal tissues. Knockdown of NEDD9 expression can restrain the proliferation, invasion and migration of EC109 cells.

  8. NEDD9 was able to partially overcome the inhibitory effects of miR-203 on colorectal cancer cell colony formation and invasion.

  9. Increased NEDD9 expression is associated with metastatic endometrial and lung cancers.

  10. NEDD9 has an essential role in development as well as in neoplastic cell proliferation, apoptosis, adhesion, migration and invasion. (Review)

  11. The presence of the dna fragment in the NSCLC-N6-L16 cell ChIP assays demonstrated a physical link between NEDD9 and p53.

  12. siRNA suppression of NEDD9 inhibits proliferation and enhances apoptosis in renal cell carcinoma.

  13. Serum NEDD9 was elevated in gastric cancer patients and had an unfavorable prognostic effect.

  14. BCAR3 is an essential interactor and mediator of HEF1-induced migration.

  15. Study uncovers a new role of NEDD9 as a regulator of integrin trafficking through CAV1-dependent endocytosis, and provide new insight into the regulation of migration of breast cancer cells.

  16. miR145 is inversely correlated with NEDD9 expression in pancreatic cancer tissues and restoration of miR145 in Panc1 cells reduced NEDD9 mRNA and protein expression accompanied by inhibition of cell proliferation, invasion and migration.

  17. Results establish a novel role for NEDD9 as a key regulator of Arf6-dependent trafficking of MMP14 and its invasive properties, highlighting the basic mechanism utilized by NEDD9 to support breast cancer cell invasion and metastasis.

  18. discuss emerging evidence supporting involvement of NEDD9 in additional pathological conditions, including stroke and polycystic kidney disease

  19. our findings suggest that NEDD9 acts as an oncogene and promotes GC metastasis via EMT.

  20. The expression of Nedd9 was upregulated in gastric cancer, high expression of Nedd9 significantly correlated with cancer progression and poor prognosis in gastric cancer.

Mouse (Murine) Neural Precursor Cell Expressed, Developmentally Down-Regulated 9 (NEDD9) Interaktionspartner

  1. a new role for Cas-L in T-cell activation, is reported.

  2. These results suggest that Nedd9 is a Smad2/3 target gene implicated in RANKL-induced osteoclastogenesis.

  3. NEDD9 is required for the maintenance of dendritic spines in the hippocampus.

  4. NEDD9 has an essential role in development as well as in neoplastic cell proliferation, apoptosis, adhesion, migration and invasion. (Review)

  5. Thus the RARE upstream of the Nedd9 2B promoter is necessary for much of the endogenous gene expression during early development as well as ectopic expression in response to atRA.

  6. suggest that Cas-L/NEDD9 plays a pivotal role in the pathophysiology of CIA, and that Cas-L/NEDD9 may be a potential molecular target for the treatment of RA

  7. Data indicate that Src kinase modulates the transit time of NEDD9 (neural precursor cell expressed developmentally down-regulated gene 9) at focal adhesion sites.

  8. These results indicated an important modifier action of Nedd9 on autosomal dominant polycystic kidney disease pathogenesis involving failure to activate Aurora-A.

  9. these results indicate a functional requirement for NEDD9 in the growth of mammary cancer progenitor cells

  10. Tyrosine Y189 in the substrate domain of the adhesion docking protein NEDD9 is conserved with p130Cas Y253 and regulates NEDD9-mediated migration and focal adhesion dynamics.

  11. Collectively our data suggest that NEDD9 may promote 3D cell migration by slowing focal adhesion disassembly, promoting integrin receptor activation and increasing adhesion force

  12. Myosin IIA inhibition also significantly reduces phosphorylation of the mechanosensing protein CasL (Crk-associated substrate the lymphocyte type), raising the possibility of a direct mechanical mechanism of signal modulation involving CasL.

  13. Cas-L seems to regulate the progression of CML in a negative way, presumably by attenuating extramedullary hyperplasia

  14. Cas proteins do not affect E-cadherin transcription, but rather, BCAR1 and NEDD9 signal through SRC to promote E-cadherin removal from the cell membrane and lysosomal degradation.

  15. Mammary tumor cells lacking NEDD9 is associated with enhanced genetic instability and dasatinib sensitivity.

  16. SHEP1 and CasL are constitutively associated in B cells.

  17. Cas-L affects homeostasis of MZB cells and peripheral lymphoid organs, which is considered to be relevant to impaired lymphocyte migration and adhesion

  18. Nedd9 has a role in the differentiation of neurons after ischemia

  19. Cellular localization of NEDD9 expression during embryonic development.

  20. Nedd9 promotes the migration of NCCs in a graded manner and suggest a role for RA in the control of Nedd9 expression levels.

NEDD9 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a member of the CRK-associated substrates family. Members of this family are adhesion docking molecules that mediate protein-protein interactions for signal transduction pathways. This protein is a focal adhesion protein that acts as a scaffold to regulate signaling complexes important in cell attachment, migration and invasion as well as apoptosis and the cell cycle. This protein has also been reported to have a role in cancer metastasis. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit NEDD9

  • neural precursor cell expressed, developmentally down-regulated 9 (NEDD9) Antikörper
  • neural precursor cell expressed, developmentally down-regulated 9 (Nedd9) Antikörper
  • neural precursor cell expressed, developmentally down-regulated gene 9 (Nedd9) Antikörper
  • Cas-L Antikörper
  • CAS2 Antikörper
  • CasL Antikörper
  • CASS2 Antikörper
  • E230025G09Rik Antikörper
  • HEF1 Antikörper
  • NEDD9 Antikörper

Bezeichner auf Proteinebene für NEDD9

neural precursor cell expressed, developmentally down-regulated 9 , enhancer of filamentation 1 homolog , Cas scaffolding protein family member 2 , Crk-associated substrate related protein Cas-L , Enhancer of filamentation 1 p55 , cas-like docking , enhancer of filamentation 1 , neural precursor cell expressed developmentally down-regulated protein 9 , p130Cas-related protein , renal carcinoma antigen NY-REN-12 , neural precursor cell expressed, developmentally down-regulated gene 9 , CRK-associated substrate-related protein , Crk-associated substrate lymphocyte-specific protein , NEDD-9 , mEF1 , p105

GENE ID SPEZIES
395736 Gallus gallus
462433 Pan troglodytes
100063890 Equus caballus
100154178 Sus scrofa
100229910 Taeniopygia guttata
100606649 Nomascus leucogenys
4739 Homo sapiens
291044 Rattus norvegicus
18003 Mus musculus
488220 Canis lupus familiaris
Ausgewählte Anbieter für NEDD9 (NEDD9) ELISA Kits
Haben Sie etwas anderes gesucht?