Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) ELISA Kits

displays differential expression after induction by nerve growth factor [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen NEDD8 Antikörper (149) und NEDD8 Proteine (29) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
NEDD8 4738 Q15843
NEDD8 18002 P29595
NEDD8 25490 Q71UE8
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Top NEDD8 ELISA Kits auf antikoerper-online.de

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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 9.77 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$910.56
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Human
  96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$380.00
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Human
  96 Tests Anmelden zum Anzeigen 31 bis 41 Tage
$728.20
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Human
  1 kit Anmelden zum Anzeigen 5 bis 8 Tage
$923.19
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Weitere ELISA Kits für NEDD8 Interaktionspartner

Human Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) Interaktionspartner

  1. NEDD8-mediated neddylation promotes stress granule assembly.

  2. NEDD8 seems to inhibit the Src (zeige SRC ELISA Kits)-mediated phosphorylation of caveolin-1 (zeige CAV1 ELISA Kits) by modifying the structure of caveolin-1 (zeige CAV1 ELISA Kits) protein, which blocks the migration of cancer cells. Although the neddylation process is currently regarded as an emerging target for cancer therapy, our results suggest the possibility that the inhibition of neddylation could facilitate cancer invasion or metastasis at least in some types of cancers.

  3. The cellular effects of NEDD8 inhibition can be manipulated based on the p53 (zeige TP53 ELISA Kits) status.

  4. Here we report that high expression of neddylation components, NEDD8 and NAE1, are associated with poor survival of Pancreatic ductal adenocarcinoma patients. Blockage of neddylation by MLN4924 significantly sensitizes pancreatic cancer cells to gemcitabine, reduced clonogenic survival, decreased invasion capacity, increased apoptosis and senescence

  5. Downregulation of NEDD8 enhanced the susceptibility of nasopharyngeal carcinoma cells to cisplatin and radiation.

  6. Furthermore, the authors characterized SENP8/DEN1 (zeige SENP8 ELISA Kits) as the protease that counteracts Ubc12 auto-neddylation, and observed aberrant neddylation of Ubc12 and other NEDD8 conjugation pathway components in SENP8 (zeige SENP8 ELISA Kits)-deficient cells.

  7. MKK7 (zeige MAP2K7 ELISA Kits) undergoes neddylation in human breast cancer cells

  8. complete blocking of CRLs at a higher inhibitor dose-induced cytotoxicity that was amplified by knockdown of CRL (zeige IL31RA ELISA Kits) regulator Cand1 (zeige CAND1 ELISA Kits).

  9. In conclusion, the authors revealed that E3 ligase HDM2 promotes NEDD8 NEDDylation of HBx to enhance HBx stability and chromatin localization, which in turn favors HBx-dependent transcriptional regulation, cell proliferation, and hepatitis B virus-driven tumor growth.

  10. CUL5 (zeige CUL5 ELISA Kits) neddylation may allosterically tune polyubiquitin (zeige UBB ELISA Kits) chain length and topology.

Mouse (Murine) Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) Interaktionspartner

  1. Downregulation of NEDD8 enhanced the susceptibility of nasopharyngeal carcinoma cells to cisplatin and radiation.

  2. Data show that NEDL2 regulates GDNF/Ret/Akt pathway depends on its Nedd8 ligase activity rather than ubiquitin ligase activity.

  3. neural precursor cell expressed developmentally downregulated protein 8 (Nedd8) modification of Cul-5 (zeige CUL5 ELISA Kits) is required for its interaction with TRAF6 (zeige TRAF6 ELISA Kits).

  4. Our findings provide mechanistic evidence of the effects of IAP (zeige ALPI ELISA Kits) antagonists in combination with NAE inhibitors, and demonstrate the potential of a new combination therapy for cancer.

  5. a role of Nedd8 in regulating caspase-1 (zeige CASP1 ELISA Kits) activation following inflammasome activation

  6. Nedd8 and its associated E2 carrier protein (Ubc12) and E3-SCF (zeige KITLG ELISA Kits) ligase play a key role in regulating the expression and activity of ENaC (zeige SCNN1A ELISA Kits) in alveolar pneumocytes.

  7. a new regulatory mechanism of RCAN1 (zeige RCAN1 ELISA Kits) function

  8. c-Cbl conjugates neural precursor cell-expressed, developmentally downregulated 8 (NEDD8), a ubiquitin-like protein, to TbetaRII at Lys556 and Lys567.

  9. The NEDD8 pathway appears to play an important role in CD4 (zeige CD4 ELISA Kits)+ T-cell-mediated inflammatory responses

  10. Nedd8 and AhR (zeige AHR ELISA Kits) localize to overlapping areas in the heart and spinal ganglia, raising the possibility that this interaction may play a role in organogenesis

Fruit Fly (Drosophila melanogaster) Neural Precursor Cell Expressed, Developmentally Down-Regulated 8 (NEDD8) Interaktionspartner

  1. the Cul1 (zeige CUL1 ELISA Kits)-based SCF (zeige KITLG ELISA Kits) complex requires Nedd8 modification for the degradation processes of Ci, Arm, and CycE (zeige CCNE1 ELISA Kits) in vivo

  2. Genetic analyses indicate that a balance between neddylation and deneddylation maintained by DEN1 (zeige SENP8 ELISA Kits) is crucial for animal viability.

NEDD8 Antigen-Profil

Beschreibung des Gens

displays differential expression after induction by nerve growth factor

Genbezeichner und Symbole assoziert mit NEDD8

  • neural precursor cell expressed, developmentally down-regulated 8 (NEDD8) Antikörper
  • neural precursor cell expressed, developmentally down-regulated gene 8 (Nedd8) Antikörper
  • neural precursor cell expressed, developmentally down-regulated 8 (Nedd8) Antikörper
  • CG10679 gene product from transcript CG10679-RB (Nedd8) Antikörper
  • neural precursor cell expressed, developmentally down-regulated 8 (nedd8) Antikörper
  • Nedd8 (Nedd8) Antikörper
  • ubiquitin-like protein Nedd8 (nedd8) Antikörper
  • neural precursor cell expressed, developmentally down-regulated 8 L homeolog (nedd8.L) Antikörper
  • CG10679 Antikörper
  • DDBDRAFT_0218116 Antikörper
  • DDBDRAFT_0238041 Antikörper
  • DDB_0218116 Antikörper
  • DDB_0238041 Antikörper
  • Dmel\\CG10679 Antikörper
  • dNEDD8 Antikörper
  • GB17785 Antikörper
  • NEDD-8 Antikörper
  • nedd8 Antikörper
  • nedd8.S Antikörper
  • Rub1 Antikörper
  • si:zc14a17.5 Antikörper
  • ubiquitin Antikörper

Bezeichner auf Proteinebene für NEDD8

neddylin , ubiquitin-like protein Nedd8 , NEDD-8 , NEDD8 , neural precursor cell expressed developmentally down-regulated protein 8 , neural precursor cell expressed, developmentally down-regulated gene 8 , CG10679-PA , Nedd8-PA , neural precursor cell-expressed developmentally downregulated , neural precursor cell expressed, developmentally down-regulated 8 , Nedd8 , NEDD8 protein , neural precursor cell expressed, developmentally down-regulated 8 S homeolog

GENE ID SPEZIES
4738 Homo sapiens
18002 Mus musculus
25490 Rattus norvegicus
35151 Drosophila melanogaster
286796 Bos taurus
368667 Danio rerio
480265 Canis lupus familiaris
549727 Xenopus (Silurana) tropicalis
552822 Apis mellifera
715763 Macaca mulatta
8621655 Dictyostelium discoideum AX4
100009008 Oryctolagus cuniculus
100301786 Oncorhynchus mykiss
100528101 Ictalurus punctatus
100520086 Sus scrofa
446966 Xenopus laevis
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