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NOX3 encodes a member of the NOX family of NADPH oxidases. Zusätzlich bieten wir Ihnen NOX3 Proteine (7) und NOX3 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 59 products:
Mouse (Murine) Polyclonal NOX3 Primary Antibody für IHC - ABIN966689
Chéret, Gervais, Lelli, Colin, Amar, Ravassard, Mallet, Cumano, Krause, Mallat: Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2008
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Human Polyclonal NOX3 Primary Antibody für IHC - ABIN966688
Cheng, Cao, Xu, van Meir, Lambeth: Homologs of gp91phox: cloning and tissue expression of Nox3, Nox4, and Nox5. in Gene 2001
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Human Polyclonal NOX3 Primary Antibody für IHC, ELISA - ABIN1535076
Du, Yang, Hu, Sun, Zhang, Peng, Zhong, Huang, Kong: A long-term high-fat diet increases oxidative stress, mitochondrial damage and apoptosis in the inner ear of D-galactose-induced aging rats. in Hearing research 2012
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Human Polyclonal NOX3 Primary Antibody für IF (p), IHC (p) - ABIN702595
Wakatsuki, Furuno, Ohshima, Araki: Oxidative stress-dependent phosphorylation activates ZNRF1 to induce neuronal/axonal degeneration. in The Journal of cell biology 2015
Hsp70 (zeige HSP70 Antikörper) activates Stat3 (zeige STAT3 Antikörper) and suppresses Nox3 via TLR4 (zeige TLR4 Antikörper)
Together, these findings reveal that Nox2 (zeige CYBB Antikörper) is a Zn(2+)-regulated enzyme that mediates ZnD-induced oxidative stress and kidney hypertrophy. Understanding the specific mechanisms by which ZnD contributes to kidney damage may have an important impact on the treatment of chronic kidney disease.
Nox3 mutants and heterozygotes demonstrated a greater susceptibility to noise-induced hearing loss.
Although Nox3 overexpression revealed no apparent effect, depletion of Nox3 decreased the number of spermatogonial stem cells in both cultured spermatogonia and freshly isolated testis cells.
Mutations of Nox3 include retrovirus insertion, missense mutations, splice donor mutation, a splice acceptor mutation and premature translational termination.
palmitate-induced ROS (zeige ROS1 Antikörper) generation and that NOX3-derived ROS (zeige ROS1 Antikörper) may drive palmitate-induced hepatic insulin (zeige INS Antikörper) resistance through JNK (zeige MAPK8 Antikörper) and p38(MAPK (zeige MAPK14 Antikörper)) pathways.
an allelic series of mutations at the otoconia-deficient head tilt (het) locus, affecting the gene for NADPH oxidase 3 (Nox3), identifies Nox3 as a protein with a clear enzymatic function indispensable for otoconia morphogenesis
NOX3 is a relevant source of ROS (zeige ROS1 Antikörper) generation in the cochlear and vestibular systems and that NOX3-dependent ROS (zeige ROS1 Antikörper) generation might contribute to hearing loss and balance problems in response to ototoxic drugs.
genetic variants in NOX3 may confer susceptibility to antithyroid drug-induced apoptosis of granulocytes.
In lung transplants, our study highlights a donor-recipient interaction of NOX3 and NFE2L2 (zeige NFE2L2 Antikörper) that increases the risk of PGD (zeige PGD Antikörper).
Reduced matrigel invasion was mediated by reduced ROS (zeige ROS1 Antikörper) levels coinciding with decreased expression of NADPH oxidase 2 (zeige CYBB Antikörper), 3, 4 and 5 involved in ROS (zeige ROS1 Antikörper) production.
Down-regulation of NOX3 using siRNA prevented TNF-alpha (zeige TNF Antikörper)-induced decrease of cellular glycogen (zeige GYS1 Antikörper).
Nox3 is regulated by NOXO1 (zeige NOXO1 Antikörper), p47phox, and p67phox (zeige NCF2 Antikörper)
Nox3 functions together with p22(phox (zeige CYBA Antikörper)) as an enzyme constitutively producing superoxide
Rac1 regulates both oxidases Nox1 (zeige NOX1 Antikörper) and Nox3 through the Nox activators
In conclusion, the results demonstrate that NOX3, a reactive oxygen species generating NADPH oxidase (zeige NOX1 Antikörper), plays an integral role in insulin (zeige INS Antikörper)-induced p42 (zeige EPB42 Antikörper)/44 Mitogen-activated protein kinase (zeige MAPK1 Antikörper) signal transmission and VEGF-A (zeige VEGFA Antikörper) production.
Roles for p22phox (zeige CYBA Antikörper) at several distinct points in the maturation and assembly of a functionally competent Nox3 in the plasma membrane.
This gene encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.
, NADPH oxidase catalytic subunit-like 3
, gp91phox homolog 3
, mitogenic oxidase 2
, NADPH oxidase 3
, predicted NADPH oxidase-3
, NADPH oxidase 3-like