NAD(P)H Dehydrogenase, Quinone 1 Proteine (NQO1)

NQO1 is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. Zusätzlich bieten wir Ihnen NQO1 Antikörper (216) und NQO1 Kits (30) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
NQO1 1728 P15559
NQO1 24314 P05982
NQO1 18104 Q64669
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Top NQO1 Proteine auf antikoerper-online.de

Showing 10 out of 14 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
Details
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$4,744.22
Details
Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$775.00
Details
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
$860.20
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
$2,713.33
Details
Escherichia coli (E. coli) Human His tag   1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$5,769.50
Details
Escherichia coli (E. coli) Human S tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$720.00
Details
Escherichia coli (E. coli) Ratte T7 tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$749.00
Details
Escherichia coli (E. coli) Maus S tag,His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$768.00
Details

NQO1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, , ,
Rat (Rattus) ,
,
Mouse (Murine)
,

Weitere Proteine zu NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Interaktionspartnern

Zebrafish NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Interaktionspartner

  1. Coptisine exerted its antioxidant activity against AAPH-induced toxicity involving in activating Akt (zeige AKT1 Proteine) and JNK (zeige MAPK8 Proteine)/Nrf2 (zeige NFE2L2 Proteine)/NQO1 pathway.

Human NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Interaktionspartner

  1. These results indicate that dual-negative expression of Nrf2 (zeige GABPA Proteine) and NQO1 is predictive of a better prognosis in NSCLC patients.

  2. Case-control study found a significant difference was observed between large artery atherosclerotic ischemic stroke patients and controls with respect to the CYP2E1 (zeige CYP2E1 Proteine)*5B genotype and allele distribution. NQO1*2 polymorphism genotype distribution was significantly different between patients and controls and heterozygote *1*2 genotype was found to be a protective factor against large artery atherosclerotic ischemic stroke.

  3. the NQO1 Pro187Ser or SULT1A1 (zeige SULT1A1 Proteine) Arg213His polymorphism combination with smoking significantly confer susceptibility to BC. [META-ANALYSIS]

  4. Docosahexaenoic acid (DHA) activates Nrf2 (zeige GABPA Proteine), possibly through modification of critical Keap1 (zeige KEAP1 Proteine) cysteine 288 residue and PKCdelta (zeige PKCd Proteine)-mediated phosphorylation of Nrf2 (zeige GABPA Proteine), leading to upregulation of HO-1 (zeige HMOX1 Proteine) and NQO1 expression.

  5. the upregulation of Cav1 (zeige CAV1 Proteine) contributed to the DHA-mediated p53 (zeige TP53 Proteine) activation and the downregulation of the redox enzyme, NAD(P)H:quinone oxidoreductase 1 (NQO1), which have been reported to contribute to the activation of the cell death pathway.

  6. NQO1 may act as a redox-dependent switch where the protein responds to the NAD(P)+/NAD(P)H redox environment by altering its structure promoting the binding or dissociation of NQO1 with target macromolecules

  7. Taken together, we proposed that NQO1 could potentiate NSCLC cell proliferation by enhancing cellular glycometabolism, and HKII (zeige HK2 Proteine) is a key mediator of this mechanism.

  8. The higher incidence of NQO1 mutants among bronchopulmonary dysplasia (BPD) neonates as well as the presence of the mutant allele in all neonates with <= 1,000 g who developed BPD provided the first evidence for a possible pathogenetic role of the C(609)T polymorphism in BPD susceptibility due to the reduction or loss of NQO1 enzymatic activity.

  9. Activity of the enzyme NQO1 does not appear to be developmentally regulated, with levels of hepatic activity as high in neonates and children as they are in adults. Obesity may increase hepatic NQO1 activity in children.

  10. Novel RNA-binding activity of NQO1 promotes SERPINA1 (zeige SERPINA1 Proteine) mRNA translation.

Mouse (Murine) NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Interaktionspartner

  1. Novel RNA-binding activity of NQO1 promotes SERPINA1 (zeige SERPINA1 Proteine) mRNA translation.

  2. NQO1 and autophagy participate in a protective role in cisplatin injury.

  3. A significant increase was found in Nrf2 (zeige NFE2L2 Proteine)-ARE activity after partial hepatectomy (PHx). The signal maximum was recorded on the third day after PHx. Significantly more hepatocytes were positive for Nrf2 (zeige NFE2L2 Proteine) and HO-1 (zeige HMOX1 Proteine) on the third postoperative day compared with baseline levels. The mRNA expression of HO-1 (zeige HMOX1 Proteine) and NQO1 were significantly increased on day 3.

  4. Miroestrol restored hepatic NQO1 expression in beta-naphthoflavone-treated mice.

  5. previous and present results collectively show that NQO1 is involved in the formation of tight junctions in the small intestine, and that defects in NQO1 enhance C. difficile toxin A-induced acute inflammatory responses, presumably via the loss of epithelial cell tight junctions

  6. NQO1 plays a critical role in protection against energy depletion in acetaminophen-induced liver injury, and is associated with improvement of mitochondrial dysfunction

  7. The present results demonstrate that exacerbated cisplatin-induced nephrotoxicity under the NQO1-knockout condition was accompanied by the reduced expression of MRN complex proteins, ATM (zeige ATM Proteine), PARP1 (zeige PARP1 Proteine), and Sirt1 (zeige SIRT1 Proteine).

  8. Taken together, these data suggest that EEEC attenuates oxidative stress by activating Nrf2 (zeige NFE2L2 Proteine)-mediated HO-1 (zeige HMOX1 Proteine) and inducing NQO-1 via the activation of MAPK (zeige MAPK1 Proteine) signaling pathways.

  9. We defined the basal and butylated hydroxyanisole induced expression patterns of Nqo1, AKR1B8, and Ho-1 (zeige HMOX1 Proteine) in the liver and small intestine of C57BL/6 mice.

  10. The colons of NQO1-KO mice also showed high levels of reactive oxygen species (ROS (zeige ROS1 Proteine)) and histone deacetylase (HDAC (zeige HDAC1 Proteine)) activity, which are known to affect transcriptional regulation.

Pig (Porcine) NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Interaktionspartner

  1. The obtained data convincingly showed that porcine NADPH-d cells may produce nitric oxide.

  2. Immunoreactivity of eNOS (zeige NOS3 Proteine) was similar to NADPH-d staining. Clear iNOS (zeige NOS2 Proteine) immunoreactivity was detected in the luminal epithelium, endometrial stroma and individual endometrial glands.

Cow (Bovine) NAD(P)H Dehydrogenase, Quinone 1 (NQO1) Interaktionspartner

  1. NQO1 expression was increased in the ruminal papillae of more efficient low residual feed intake (RFI (zeige RNF34 Proteine)) animals compared to the high RFI (zeige RNF34 Proteine) animals

NQO1 Protein Überblick

Protein Überblick

This gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. This FAD-binding protein forms homodimers and reduces quinones to hydroquinones. This protein's enzymatic activity prevents the one electron reduction of quinones that results in the production of radical species. Mutations in this gene have been associated with tardive dyskinesia (TD), an increased risk of hematotoxicity after exposure to benzene, and susceptibility to various forms of cancer. Altered expression of this protein has been seen in many tumors and is also associated with Alzheimer's disease (AD). Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Genbezeichner und Symbole assoziert mit NQO1

  • NAD(P)H dehydrogenase, quinone 1 (nqo1)
  • NAD(P)H quinone dehydrogenase 1 (NQO1)
  • NAD(P)H dehydrogenase, quinone 1 (Bpet2092)
  • NAD(P)H dehydrogenase, quinone 1 L homeolog (nqo1.L)
  • NAD(P)H quinone dehydrogenase 1 (nqo1)
  • NAD(P)H quinone dehydrogenase 1 (Nqo1)
  • NAD(P)H dehydrogenase, quinone 1 (Nqo1)
  • AV001255 Protein
  • DHQU Protein
  • Dia4 Protein
  • Dtd Protein
  • NADPH-d Protein
  • Nmo-1 Protein
  • Nmo1 Protein
  • Nmor1 Protein
  • NMORI Protein
  • nqo1 Protein
  • Ox-1 Protein
  • Ox1 Protein
  • Qr1 Protein
  • wu:fb63c10 Protein
  • zgc:77191 Protein

Bezeichner auf Proteinebene für NQO1

NAD(P)H dehydrogenase [quinone] 1 , NAD(P)H menadione oxidoreductase 1, dioxin-inducible , NAD(P)H dehydrogenase, quinone 1 , DT-diaphorase , DTD , NAD(P)H:quinone oxidoreductase 1 , QR1 , azoreductase , menadione reductase , phylloquinone reductase , quinone reductase 1 , nad(p)h dehydrogenase (quinone) 1 , NAD(P)H:Quinone acceptor oxidoreductase type 1 , NAD(P)H:menadione oxidoreductase 1 , NAD(P)H:quinone oxireductase , diaphorase (NADH/NADPH) (cytochrome b-5 reductase) , diaphorase-4 , dioxin-inducible 1 , Diaphorase (NADH/NADPH) , NAD(P)H:menadione oxidoreductase , NAD(P)H dehydrogenase (quinone) , NAD(P)H menadione oxidoreductase 1, dioxin inducible , diaphorase 4 (NADH/NADPH) , nicotinamide adenine dinucleotide phosphate diaphorase , diaphorase 4 , NAD(P)H: quinone oxidoreductase 1

GENE ID SPEZIES
322506 Danio rerio
468012 Pan troglodytes
549222 Xenopus (Silurana) tropicalis
705635 Macaca mulatta
769737 Gallus gallus
4606922 Azoarcus sp. BH72
5818094 Bordetella petrii DSM 12804
100049751 Xenopus laevis
100172039 Pongo abelii
100528193 Ictalurus punctatus
1728 Homo sapiens
610935 Canis lupus familiaris
24314 Rattus norvegicus
18104 Mus musculus
100286873 Sus scrofa
519632 Bos taurus
100135582 Cavia porcellus
Ausgewählte Anbieter für NQO1 Proteine (NQO1)
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