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The protein encoded by NTAN1 functions in a step-wise process of protein degradation through the N-end rule pathway. Zusätzlich bieten wir Ihnen N-terminal Asparagine Amidase Proteine (5) und N-terminal Asparagine Amidase Kits (3) und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal NTAN1 Primary Antibody für IHC (fro), IHC (p) - ABIN262613
Csencsits, Jutila, Pascual: Nasal-associated lymphoid tissue: phenotypic and functional evidence for the primary role of peripheral node addressin in naive lymphocyte adhesion to high endothelial venules in a mucosal site. in Journal of immunology (Baltimore, Md. : 1950) 1999
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Mouse (Murine) Monoclonal NTAN1 Primary Antibody für BR, IHC (fro) - ABIN967387
Berg, Robinson, Warnock, Butcher: The human peripheral lymph node vascular addressin is a ligand for LECAM-1, the peripheral lymph node homing receptor. in The Journal of cell biology 1991
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when embryonic 12-day-old or newborn mice were successively exposed to magnetic fields Ntan1 mRNA was significantly increased
Results indicate that hNTAN1 is highly selective for the hydrolysis of N-terminal peptidyl L-Asn.
The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway. This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp. L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome. Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
N-terminal asparagine amidohydrolase
, asparagine-specific N-terminal amidase
, protein N-terminal Asn amidase
, protein N-terminal asparagine amidohydrolase
, protein NH2-terminal asparagine amidohydrolase
, protein NH2-terminal asparagine deamidase
, protein NTN-amidase