N-Myc Downstream Regulated 1 (NDRG1) ELISA Kits

NDRG1 is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. Zusätzlich bieten wir Ihnen N-Myc Downstream Regulated 1 Antikörper (192) und N-Myc Downstream Regulated 1 Proteine (16) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
NDRG1 10397 Q92597
NDRG1 17988 Q62433
NDRG1 299923 Q6JE36
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Top N-Myc Downstream Regulated 1 ELISA Kits auf antikoerper-online.de

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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Lieferzeit Preis Details
Human 7 pg/mL 28-1800 pg/mL Typical standard curve 96 Tests 15 bis 18 Tage
  96 Tests 11 bis 18 Tage
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Rind (Kuh)
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Weitere ELISA Kits für N-Myc Downstream Regulated 1 Interaktionspartner

Human N-Myc Downstream Regulated 1 (NDRG1) Interaktionspartner

  1. We propose a nucleolar role of TARG1 in ribosome assembly or quality control that is stalled when TARG1 is re-located to sites of DNA damage.

  2. this is the first paper to reveal that different fragments of the same lncRNA, NDRG1-OT1, could produce opposite effects within a single target gene, NDRG1.

  3. Up-regulation of NDRG1 by DpdtC is a promising therapeutic approach in HER2-overexpressed cancers.

  4. The NDRG1 promotes EGFR down-regulation through the EGFR inhibitor MIG6, which leads to late endosomal/lysosomal processing of EGFR.

  5. Our findings suggest that NDRG1 positively regulates haemangioma proliferation.

  6. our findings show that NDRG1 is a critical regulator of lipid fate in breast cancer cells. The association between NDRG1 and poor prognosis in breast cancer suggests it should play a more prominent role in patient risk assessment. The function of NDRG1 in breast cancer lipid metabolism may represent a promising therapeutic approach in the future.

  7. Up-regulation of the kinase gene SGK1 by progesterone activates the AP-1-NDRG1 axis in both PR-positive and -negative breast cancer cells

  8. Data demonstrated that NDRG1 is critical for mediating LANA to recruit PCNA onto terminal repeat (TR) of KSHV genome, and facilitates viral DNA replication and episome persistence. Findings suggest that NDRG1 plays an important role in KSHV viral genome replication, and provide new clues for understanding of KSHV persistence.

  9. NDRG1 plays a positive role in highly pathogenic avian influenza A/H5N1 virus replication by suppressing the canonical NF-kappaB signaling pathway.

  10. NDRG1 disruption alleviates cisplatin/sodium glycididazole-induced DNA damage response and apoptosis in ERCC1-defective lung cancer cells

  11. Study suggests that the higher NDRG1 expression may be associated with the radio-resistance of human rectal cancer cells, and it can be a potential therapeutic target for re-sensitizing radio-resistant rectal cancer cells to ionizing radiation.

  12. Findings indicate the regulatory mechanism of microrchidia family CW-type zinc finger 2 (MORC2) in downregulating N-myc downstream-regulated gene 1 protein (NDRG1), and suggest MORC2 as a potential therapeutic target for colorectal cancer (CRC).

  13. These findings indicate that NDRG1 expression is associated with both prognosis and c-Myc expression in lung adenocarcinoma

  14. Meta-analysis showed that low NDRG1 expression was significantly associated with worse survival in colorectal cancer and pancreatic cancer but higher survival of patients with liver cancer and gallbladder cancer. No significant association was observed between low NDRG1 expression and survival in gastric cancer or esophageal cancer.

  15. Findings indicate a positive feedback loop between cancer associated fibroblast (CAFs) and box Q1 (FOXQ1)/N-myc downstream-regulated gene 1 (NDRG1) axis in neoplastic cells to drive hepatocellular carcinoma (HCC) initiation, suggesting new potential therapeutic targets for HCC.

  16. In summary, CAPE attenuates Nasopharyngeal carcinoma (NPC)cell proliferation and invasion by upregulating NDRG1 expression via MAPK pathway and by inhibiting phosphorylation of STAT3. Considering the poor prognosis of NPC patients with metastasis, CAPE could be a promising agent against NPC.

  17. These results indicate the N-terminus region and phosphorylation at Ser330 could be crucial for NDRG1 nuclear localization and function. PTEN silencing indicated that p-NDRG1 (Thr346) could be regulated differentially in different tumor cell-types, indicating PTEN may be involved in the mechanism(s) underlying the pleiotropic activity of NDRG1.

  18. present study shows that HER4 and/or NDRG1 might play a critical role for the cell survival and chemo-resistance of Osteosarcoma (OS), and could be used as potential therapeutic targets in OS.

  19. our study described two homozygous missense mutations in NDRG1 in CMT patients and mentioned the function of NDRG1 in protein recycling, which plays an important role in myelination of the peripheral nerve system.

  20. NDRG1 over-expression promoted apoptosis in colorectal cancer cells whereas depletion of NDRG1 resulted in resistance to oxaliplatin treatment.

Mouse (Murine) N-Myc Downstream Regulated 1 (NDRG1) Interaktionspartner

  1. Ndr1 is important regulator of the retinal interneurons.

  2. we show that induction of Ndrg1 expression by Ppargamma and its phosphorylation by Sgk1 kinase are required for the acquisition of adipocyte characteristics by precursor cells.

  3. Downregulated NDR1 protein kinase inhibits innate immune response by initiating an miR146a-STAT1 feedback loop.

  4. NDR1 interacts with TRAF3 and interferes with the association of TRAF3 and IL-17R, resulting in increased formation of the activation complex IL-17R-Act1, which is required for the downstream signaling and production of pro-inflammatory factors

  5. NDR1 kinase, activated by the Rap1 signaling cascade through RAPL and Mst1/Mst2, associated with and recruited kindlin-3 to the immunological synapses, which was required for high-affinity LFA-1/ICAM-1 binding.

  6. Snell, GHKRO, and PAPPA-KO mice express high levels of two proteins involved in DNA repair, O-6-methylguanine-DNA methyltransferase (MGMT) and N-myc downstream-regulated gene 1 (NDRG1).

  7. NDRG1 deficiency attenuates the differentiation of macrophage lineage cells, suppressing bone remodeling and inflammatory angiogenesis. This study strongly suggests the crucial role of NDRG1 in differentiation process for macrophages.

  8. Using double knockout of NDR1 and 2 shows that NDRs acted downstream of MST1 to mediate the egress of mature thymocytes from the thymus, as well as the interstitial migration of naive T cells within popliteal lymph nodes.

  9. Ndrg1 is phosphorylated and degraded by CD28 signalling in a proteasome-dependent manner.

  10. Ndr1/2-double null embryos show defects in somitogenesis and cardiac looping, which reveals their essential functions and shows that the NDR kinases are critically required during the early phase of organogenesis

  11. Rassf5 and Ndr1 or Ndr2 kinases regulate neuronal polarity through Par3 phosphorylation.

  12. NDRG1 promotes fetal growth and regulates the metabolic response to intrauterine hypoxic injury in a sexually dichotomous manner

  13. early growth response 1, a transcription factor that binds to the NDRG1 promoter, was mediated in the NDRG1 expression regulation by PKD2.

  14. Our findings do not support the proposed roles of NDRG1 in growth arrest, terminal differentiation, gene expression regulation and proteasomal degradation.

  15. may be a mast cell maturation-associated inducible protein that allows the cells to be susceptible to extracellular stimuli leading to degranulation

  16. Nickel induces HIF-1 transactivation and Cap43 protein expression through a PI-3K/Akt-dependent and p70(S6k)-independent pathway.

  17. results indicate that NDRG1 deficiency leads to Schwann cell dysfunction, suggesting that NDRG1 is essential for maintenance of the myelin sheaths in peripheral nerves

  18. NDRG1 may play an important role in the terminal differentiation of Schwann cells during nerve regeneration.

  19. Our data predict that the loss of NDRG1 leads to a Schwann cell autonomous phenotype resulting in demyelination, with secondary axonal loss.

  20. NDRG1 interacts with APO A-I and A-II and may have a role in the general mechanisms of HDL-mediated cholesterol transport

Cow (Bovine) N-Myc Downstream Regulated 1 (NDRG1) Interaktionspartner

  1. NDRG1 expression was elevated in bovine mammary tissue with mastitis and mammary epithelial cells treated by heat inactivated Escherichia coli and Staphylococcus aureus compared to normal tissue and untreated cells.

Zebrafish N-Myc Downstream Regulated 1 (NDRG1) Interaktionspartner

  1. this study shows that fish NDRG1a negatively regulates the cellular antiviral response by targeting IRF7 for ubiquitination and degradation, providing insights into the novel role of NDRG1a on the innate antiviral immune response in fish

  2. ndrg1b and fam49ab are 2 new modulators of PTEN signaling that control lymphoid differentiation in the zebrafish thymus.

Arabidopsis thaliana N-Myc Downstream Regulated 1 (NDRG1) Interaktionspartner

  1. NDR1 plays a broad role both in mediating primary cellular functions in Arabidopsis through maintaining the integrity of the cell wall-plasma membrane connection and as a key signaling component of these responses during pathogen infection.

  2. SR1 plays an important role in plant immunity and ethylene signaling by directly regulating NDR1 and EIN3.

  3. The induction of defence responses and disease resistance to X. campestris pv. campestris strain 8004 requires NDR1 , RAR1 and SGT1b, suggesting that effector-triggered immunity plays a large role in resistance to this strain.

  4. Sequence analysis and mass spectrometry suggest that NDR1 is localized to the PM via a C-terminal glycosylphosphatidyl-inositol (GPI) anchor.

  5. demonstrate that the RIN4-NDR1 interaction occurs on the cytoplasmically localized N-terminal portion of NDR1 and that this interaction is required for the activation of resistance signaling following infection by P. syringae

  6. Mutations in NDR1 abolished the enhanced resistance of dnd mutants against Pseudomonas syringae pv. tomato and Hyaloperonospora parasitica but not Botrytis cinerea.

N-Myc Downstream Regulated 1 (NDRG1) Antigen-Profil

Beschreibung des Gens

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein involved in stress responses, hormone responses, cell growth, and differentiation. The encoded protein is necessary for p53-mediated caspase activation and apoptosis. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4D, and expression of this gene may be a prognostic indicator for several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Genbezeichner und Symbole assoziert mit NDRG1

  • N-myc downstream regulated 1 (NDRG1) Antikörper
  • N-myc downstream regulated gene 1 (Ndrg1) Antikörper
  • N-myc downstream regulated 1 (Ndrg1) Antikörper
  • N-myc downstream regulated 1 S homeolog (ndrg1.S) Antikörper
  • N-myc downstream regulated 1 (ndrg1) Antikörper
  • N-myc downstream regulated 1a (ndrg1a) Antikörper
  • Late embryogenesis abundant (LEA) hydroxyproline-rich glycoprotein family (NDR1) Antikörper
  • N-myc downstream regulated 1 L homeolog (ndrg1.L) Antikörper
  • N-myc downstream regulated 1b (ndrg1b) Antikörper
  • cap43 Antikörper
  • cb775 Antikörper
  • cmt4d Antikörper
  • DRG-1 Antikörper
  • drg1 Antikörper
  • gc4 Antikörper
  • hmsnl Antikörper
  • ndr1 Antikörper
  • NDRG1 Antikörper
  • ndrg1-a Antikörper
  • ndrg1-b Antikörper
  • ndrg1l Antikörper
  • ndrg4 Antikörper
  • Ndrl Antikörper
  • nmsl Antikörper
  • non race-specific disease resistance 1 Antikörper
  • proxy1 Antikörper
  • rit42 Antikörper
  • rtp Antikörper
  • targ1 Antikörper
  • tdd5 Antikörper
  • wu:fb60h02 Antikörper
  • xndrg1 Antikörper
  • xNDRG1-A Antikörper
  • zgc:63944 Antikörper
  • zgc:73047 Antikörper

Bezeichner auf Proteinebene für NDRG1

N-myc downstream-regulated gene 1 protein , differentiation-related gene 1 protein , nickel-specific induction protein Cap43 , protein NDRG1 , protein regulated by oxygen-1 , reducing agents and tunicamycin-responsive protein , N-myc downstream regulated 1 , protein Ndr1 , N-myc downstream regulated gene 1 , protein NDRG1-B , xNDRG1-B , protein NDRG1-like , protein NDRG1-A , xNDRG1-A , N-myc downstream regulated gene 1, like , N-myc downstream regulated gene 1b , n-myc downstream-regulated gene 1b

10397 Homo sapiens
17988 Mus musculus
299923 Rattus norvegicus
380319 Xenopus laevis
420321 Gallus gallus
464411 Pan troglodytes
482049 Canis lupus familiaris
493508 Xenopus (Silurana) tropicalis
504499 Bos taurus
792085 Danio rerio
100068997 Equus caballus
100230327 Taeniopygia guttata
100401077 Callithrix jacchus
100466806 Ailuropoda melanoleuca
100596235 Nomascus leucogenys
697752 Macaca mulatta
821607 Arabidopsis thaliana
100728790 Cavia porcellus
447720 Xenopus laevis
393665 Danio rerio
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