Mitochondrial Calcium Uptake 1 (MICU1) ELISA Kits

MICU1 encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. Zusätzlich bieten wir Ihnen MICU1 Antikörper (43) und MICU1 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
MICU1 10367 Q9BPX6
MICU1 216001 Q8VCX5
MICU1 365567 Q6P6Q9
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Top MICU1 ELISA Kits auf antikoerper-online.de

Showing 4 out of 7 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
Details
Maus < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
Details
Ratte < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
Details
Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$1,029.60
Details

Weitere ELISA Kits für MICU1 Interaktionspartner

Human Mitochondrial Calcium Uptake 1 (MICU1) Interaktionspartner

  1. Mitochondrial Ca(2 (zeige CA2 ELISA Kits)+) uptake is controlled by protein arginine methyl transferase 1 that asymmetrically methylates MICU1, resulting in decreased Ca(2 (zeige CA2 ELISA Kits)+) sensitivity. UCP2 (zeige UCP2 ELISA Kits)/3 normalize Ca(2 (zeige CA2 ELISA Kits)+) sensitivity of methylated MICU1 and, thus, re-establish mitochondrial Ca(2 (zeige CA2 ELISA Kits)+) uptake activity.

  2. MICU2 restricts spatial crosstalk between InsP3R (zeige ITPR1 ELISA Kits) and MCU (zeige MCU ELISA Kits) channels by regulating threshold and gain of MICU1-mediated inhibition and activation of MCU (zeige MCU ELISA Kits).

  3. study concludes that cooperative, high-affinity interaction of the MICU1-MICU2 complex with Ca(2 (zeige CA2 ELISA Kits)+) serves as an on-off switch, leading to a tightly controlled channel, capable of responding directly to cytosolic Ca(2 (zeige CA2 ELISA Kits)+) signals

  4. MICU1 serves as a signal-noise discriminator in mitochondrial calcium signalling, limiting the energetic costs of mitochondrial Ca2 (zeige CA2 ELISA Kits)+ signalling which may undermine oxidative phosphorylation, especially in tissues with highly dynamic energetic demands.

  5. Results showed that the SNP on EF-hand Ca2 (zeige CA2 ELISA Kits)+ binding domains of MICU1 gene had no effect in phenotypic characters of bipolar disorder patients

  6. Our experiments provide novel details about how MCU (zeige MCU ELISA Kits)/EMRE is regulated by MICU1 and an original approach to investigate MCU (zeige MCU ELISA Kits)/EMRE activation in intact cells.

  7. Data show that ribosomal protein S3 (RPS3 (zeige RPS3 ELISA Kits)) knockdown decreased mitochondrial calcium uptake 1 protein (MICU1) expression.

  8. Loss of heterozygosity of MICU1 gene on chromosome 10q is associated with pancreatic cancer.

  9. Expression of MICU1 mutants lacking functional Ca2 (zeige CA2 ELISA Kits)+-binding sites leads to a striking loss of Ca2 (zeige CA2 ELISA Kits)+ uptake in HEK293 cells.

  10. MICU1 EF hands determine MCU (zeige MCU ELISA Kits) activity, but not binding.

Mouse (Murine) Mitochondrial Calcium Uptake 1 (MICU1) Interaktionspartner

  1. MICU1 exerted protection against myocardial ischemia/reperfusion injury via prevention of mitochondrial Ca2 (zeige CA2 ELISA Kits)+ overload, preservation of mitochondrial integrity and promotion of mitochondrial energy metabolism.

  2. that MICU1 serves as a molecular gatekeeper preventing calcium overload and suggests that modulating the calcium uniporter could have widespread therapeutic benefits

  3. a possible role for tissue-specific stoichiometry between the Ca(2 (zeige CA2 ELISA Kits)+)-sensing regulators (MICUs) and pore unit (MCU (zeige MCU ELISA Kits)) of the uniporter, was investigated.

  4. A MICU1 splice variant confers high sensitivity to the mitochondrial Ca(2 (zeige CA2 ELISA Kits)+) uptake machinery of skeletal muscle.

  5. MICU1 was downregulated in db/db (zeige LEPR ELISA Kits) mouse hearts, which contributes to myocardial apoptosis in diabetes. Importantly, the reconstitution of MICU1 in diabetic hearts significantly inhibited the development of diabetic cardiomyopathy, as evidenced by enhanced cardiac function and reduced cardiac hypertrophy and myocardial fibrosis in db/db (zeige LEPR ELISA Kits) mice.

  6. MICU1 regulation of mitochondrial Ca(2 (zeige CA2 ELISA Kits)+) uptake dictates survival and liver regeneration.

MICU1 Antigen-Profil

Beschreibung des Gens

This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.

Genbezeichner und Symbole assoziert mit MICU1

  • mitochondrial calcium uptake 1 (MICU1) Antikörper
  • mitochondrial calcium uptake 1 (Micu1) Antikörper
  • C730016L05Rik Antikörper
  • Calc Antikörper
  • Cbara1 Antikörper
  • EFHA3 Antikörper

Bezeichner auf Proteinebene für MICU1

ara CALC , atopy-related autoantigen CALC , calcium uptake protein 1, mitochondrial , calcium-binding atopy-related autoantigen 1 , calcium binding atopy-related autoantigen 1 , calcium-binding atopy-related autoantigen 1 homolog

GENE ID SPEZIES
10367 Homo sapiens
216001 Mus musculus
365567 Rattus norvegicus
507899 Bos taurus
Ausgewählte Anbieter für MICU1 (MICU1) ELISA Kits
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