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This protein is ubiquitous and highly conserved. Zusätzlich bieten wir Ihnen MSRA Proteine (70) und MSRA Kits (17) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal MSRA Primary Antibody für ICC, IF - ABIN4333966
Shin, Yoon, Chun, Shin, Lee, Oh, Park: Arrest defective 1 regulates the oxidative stress response in human cells and mice by acetylating methionine sulfoxide reductase A. in Cell death & disease 2014
MsrA (zeige MSR1 Antikörper) protects against lipopolysaccharide-induced septic shock, and negatively regulates proinflammatory responses via inhibition of the ROS (zeige ROS1 Antikörper)-MAPK (zeige MAPK1 Antikörper)-NF-kappaB (zeige NFKB1 Antikörper) signaling pathways.
Collectively, our results suggest that MsrA (zeige MSR1 Antikörper) protects hepatocytes from APAP-induced cytotoxicity through the modulation of TXNRD1 (zeige TXNRD1 Antikörper) expression.
results demonstrate that MsrA (zeige MSR1 Antikörper) protects the liver from APAP-induced toxicity. The data provided herein constitute the first in vivo evidence of the involvement of MsrA (zeige MSR1 Antikörper) in hepatic function under APAP challenge
Results suggest that lower MsrA (zeige MSR1 Antikörper) activity modifies Amyloid-beta solubility properties and causes mitochondrial dysfunction in a mouse model of Alzheimer's disease.
MsrA (zeige MSR1 Antikörper) acts as a negative regulator of vascular smooth muscle cell proliferation and neointimal hyperplasia after vascular injury through control of the Ras/Raf (zeige RAF1 Antikörper)/ERK1 (zeige MAPK3 Antikörper)/ERK2 (zeige MAPK1 Antikörper) signaling pathway.
ARD1 (zeige ARD1A Antikörper) has a crucial role in the cellular response to oxidative stress as a bona fide regulator of MSRA (zeige MSR1 Antikörper).
These results suggest that COMT (zeige COMT Antikörper) activity may be reduced by methionine oxidation, and point to Msr (zeige MSR1 Antikörper) as a key molecular determinant for the modulation of COMT (zeige COMT Antikörper) activity in the brain.
The MsrA (zeige MSR1 Antikörper) and protein oxidation play a role in the regulation of glucose homeostasis.
MsrA (zeige MSR1 Antikörper) protects the kidney against I/R injury, and that this protection is associated with reduced oxidative stress and inflammatory responses.
MsrA (zeige MSR1 Antikörper) overexpression in MsrA (zeige MSR1 Antikörper)-depleted cells led to the reduction of increased HO-1 (zeige HMOX1 Antikörper) expression, and suppressed nuclear accumulation of Nrf2 (zeige NFE2L2 Antikörper).
Data show that miR (zeige MLXIP Antikörper)-193b, by directly targeting focal adhesion kinase (FAK), CRK (zeige CRK Antikörper)-like proto-oncogene (zeige RAB1A Antikörper) (CRKL (zeige CRKL Antikörper)), and methionine sulfoxide reductase A (MSRA), regulates focal adhesion signaling and ROS (zeige ROS1 Antikörper) signaling, which play pivotal roles in liposarcomagenesis and adipogenic differentiation.
this study we have identified, for the first time, compounds structurally related to the natural products fusaricidins that markedly activate recombinant bovine and human MsrA and human MsrB (zeige MSRB2 Antikörper).
The association of MsrA haplotypes with executive functions indicated that MsrA is associated with executive function defects in bipolar I disorder patients.
Silencing the expression of the main Msr elements-MsrA, MsrB1, or MsrB2 exacerbates sensitivity toward oxidative stress.
ARD1 (zeige TRIM23 Antikörper) has a crucial role in the cellular response to oxidative stress as a bona fide regulator of MSRA.
The functional MSRA rs10903323 G/A polymorphism is associated with coronary artery disease development.
We hypothesize that the activity of MsrA can be employed as a marker for the isolation of stem and progenitor cell subpopulations for cell therapy applications.
The MSRA rs10903323 G/A variant allele is associated with Rheumatoid Arthritis development, especially among male patients, older patients, C-Reactive Protein (zeige CRP Antikörper)-positive patients, and anti-cyclic citrullinated peptide negative patients.
The MSRA rs10903323 gene polymorphism may be implicated in the increased risk to develop cardiovascular events, in particular ischaemic heart disease, observed in rheumatoid arthritis patients.
Mammalian and yeast MSRA reduced free methionine sulfoxide much more efficiently than MSRB (zeige MSRB2 Antikörper).
The results indicate that thionein (T), which is formed when the zinc is removed from zinc-containing metallothionein (zeige MT Antikörper) (Zn-MT), can function as a reducing system for the Msr (zeige MTRR Antikörper) proteins because of its high content of cysteine residues.
This protein is ubiquitous and highly conserved. It carries out the enzymatic reduction of methionine sulfoxide to methionine. Human and animal studies have shown the highest levels of expression in kidney and nervous tissue. Its proposed function is the repair of oxidative damage to proteins to restore biological activity. Three transcript variants encoding different isoforms have been found for this gene.
, mitochondrial peptide methionine sulfoxide reductase
, peptide Met(O) reductase
, peptide methionine sulfoxide reductase
, peptide-methionine (S)-S-oxide reductase
, protein-methionine-S-oxide reductase
, cytosolic methionine-S-sulfoxide reductase
, peptide met (O) reductase