anti-Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) Antikörper

MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2\; MIM 608507) and DRP1 (DNM1L\; MIM 603850) (Nakamura et al., 2006 [PubMed 16936636]).[supplied by OMIM, Mar 2008].. Zusätzlich bieten wir Ihnen MARCH5 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
MARCH5 54708 Q9NX47
MARCH5 69104 Q3KNM2
MARCH5 294079  
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Top anti-MARCH5 Antikörper auf antikoerper-online.de

Showing 10 out of 55 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host:  Rabbit  Target Name:  MARCH5  Sample Type:  U937 Whole Cell lysates  Antibody Dilution:  1.0ug/ml 100 μL 2 bis 3 Tage
$319.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL 2 bis 3 Tage
$289.00
Details
Huhn Kaninchen Unkonjugiert IC, IF, WB Western blot analysis of 42068 expression in HepG2 (A), mouse brain (B) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IF, ELISA Immunofluorescence analysis of A549 cells, using MARCH5 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg 2 bis 3 Tage
$302.50
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL 2 bis 3 Tage
$446.88
Details
Human Kaninchen Unkonjugiert ELISA, IF Immunofluorescence analysis of A-549 cells, using MARCH5 polyclonal antibody . Peptide 100 μg 11 bis 12 Tage
$374.67
Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged MARCH5 is 0.3 ng/ml as a capture antibody. 100 μg 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (36.56 KDa) . 50 μL 11 bis 12 Tage
$305.71
Details
Huhn Kaninchen Unkonjugiert IF/ICC, WB 100 μL 11 bis 16 Tage
$312.70
Details

Am meisten referenzierte anti-MARCH5 Antikörper

  1. Cow (Bovine) Polyclonal MARCH5 Primary Antibody für WB - ABIN2774746 : Karbowski, Neutzner, Youle: The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division. in The Journal of cell biology 2007 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal MARCH5 Primary Antibody für ICC, IF - ABIN4332711 : Tang, Peng, Dong, Yang, Yang, Yang, Yang, Bao: MARCH5 overexpression contributes to tumor growth and metastasis and associates with poor survival in breast cancer. in Cancer management and research 2019 (PubMed)

Weitere Antikörper gegen MARCH5 Interaktionspartner

Rainbow Trout (Oncorhynchus mykiss) Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) Interaktionspartner

  1. MARCH5 gene is duplicated in rainbow trout, but only fish-specific gene copy is up-regulated after Viral hemorrhagic septicemia virus infection.

Human Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) Interaktionspartner

  1. the results of this study identified MARCH5 as a candidate oncogene in ovarian cancer and a potential target for ovarian cancer therapy.

  2. MARCH5 directly interacts with FUNDC1 to mediate its ubiquitylation at lysine 119 for subsequent degradation.

  3. These findings and data showing MARCH5-dependent degradation of MiD49 upon stress support the possibility that MARCH5 regulation of MiD49 is a novel mechanism controlling mitochondrial fission and, consequently, the cellular response to stress.

  4. Self-clearance mechanism of mitochondrial ligase MARCH5 contributes to mitochondria quality control.MARCH5 is regulated by auto-ubiquitination.

  5. MARCH5 binds MAVS only during viral stimulation when MAVS forms aggregates, and these interactions require the RING domain of MARCH5 and the CARD domain of MAVS.

  6. Our results indicate that HDAC6 is a critical regulator of MFN2 degradation by MARCH5, thus protecting mitochondrial connectivity from hypoxic stress.

  7. A fine balance of Mfn1 levels is maintained by MARCH5-mediated quality control on acetylated Mfn1.

  8. MITOL regulates ER tethering to mitochondria by activating Mfn2 via K192 ubiquitination.

  9. balance between LC1 activation by S-nitrosylation and down-regulation by MITOL is critical for neuronal cell survival

  10. MARCH5 is an authentic E3 ubiquitin ligase and catalyzes K63-linked polyubiquitination of TANK. MARCH5 modulates TLR7 signaling via releasing the inhibitory action of TANK toward TRAF6.

  11. study found that MITOL interacts with and ubiquitinates DeltaNAT-3Q71, a pathogenic ataxin-3 mutant, in mitochondria and attenuates its toxicity

  12. lack of MARCH5 results in mitochondrial elongation, which promotes cellular senescence by blocking Drp1 activity and/or promoting accumulation of Mfn1 at the mitochondria

  13. Results indicate that MITOL plays a protective role against mitochondrial dysfunction caused by the mitochondrial accumulation of mSOD1 via the ubiquitin-proteasome pathway.

  14. A novel mitochondrial ubiquitin ligase, designated MITOL, which is localized in the mitochondrial outer membrane, plays a critical role in mitochondrial dynamics through the control of mitochondrial fission proteins.

  15. MARCH-V has a crucial role in the control of mitochondrial morphology by regulating MFN2 and Drp1 activities.

  16. MARCH5 is required for DRP1-dependent mitochondrial division.

Mouse (Murine) Membrane-Associated Ring Finger (C3HC4) 5 (MARCH5) Interaktionspartner

  1. These findings suggest that MITOL plays a protective role against apoptosis in cardiomyocytes.

  2. MARCH5 binds MAVS only during viral stimulation when MAVS forms aggregates, and these interactions require the RING domain of MARCH5 and the CARD domain of MAVS.

  3. March5 is involved in maintaining mouse-ESC (mESC) pluripotency via catalysis of Prkar1a polyubiquitination and inhibition of the Raf/MEK/ERK pathway.

  4. A fine balance of Mfn1 levels is maintained by MARCH5-mediated quality control on acetylated Mfn1.

  5. MARCH5 is an authentic E3 ubiquitin ligase and catalyzes K63-linked polyubiquitination of TANK. MARCH5 modulates TLR7 signaling via releasing the inhibitory action of TANK toward TRAF6.

  6. Results indicate that MITOL plays a protective role against mitochondrial dysfunction caused by the mitochondrial accumulation of mSOD1 via the ubiquitin-proteasome pathway.

MARCH5 Antigen-Profil

Protein Überblick

MARCH5 is a ubiquitin ligase of the mitochondrial outer membrane that plays a role in the control of mitochondrial morphology by regulating mitofusin-2 (MFN2\; MIM 608507) and DRP1 (DNM1L\; MIM 603850) (Nakamura et al., 2006

Genbezeichner und Symbole assoziert mit MARCH5

  • membrane-associated ring finger (C3HC4) 5 (march5) Antikörper
  • membrane associated ring-CH-type finger 5 (MARCH5) Antikörper
  • membrane associated ring-CH-type finger 5 (march5) Antikörper
  • membrane associated ring-CH-type finger 5 L homeolog (march5.L) Antikörper
  • membrane-associated ring finger (C3HC4) 5 (March5) Antikörper
  • membrane associated ring-CH-type finger 5 (March5) Antikörper
  • 1810015H18Rik Antikörper
  • 2310008I22Rik Antikörper
  • 2700055A20Rik Antikörper
  • 5730499H23Rik Antikörper
  • E130202O05Rik Antikörper
  • Mar-05 Antikörper
  • MARCH-V Antikörper
  • MARCH5 Antikörper
  • Marchv Antikörper
  • MITOL Antikörper
  • Rnf153 Antikörper
  • zgc:162966 Antikörper

Bezeichner auf Proteinebene für MARCH5

membrane-associated ring finger (C3HC4) 5 , E3 ubiquitin-protein ligase MARCH5 , MARCH-V , membrane-associated RING finger protein 5 , membrane-associated RING-CH protein V , mitochondrial ubiquitin ligase , ring finger protein 153

GENE ID SPEZIES
100302643 Oncorhynchus mykiss
450607 Pan troglodytes
698517 Macaca mulatta
100144728 Xenopus (Silurana) tropicalis
100157340 Sus scrofa
100341637 Oryctolagus cuniculus
561952 Danio rerio
444564 Xenopus laevis
423815 Gallus gallus
54708 Homo sapiens
612766 Canis lupus familiaris
540937 Bos taurus
69104 Mus musculus
294079 Rattus norvegicus
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