Matrix Metallopeptidase 1 (Interstitial Collagenase) Proteine (MMP1)

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Zusätzlich bieten wir Ihnen MMP1 Antikörper (321) und MMP1 Kits (135) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
MMP1 4312 P03956
MMP1 300339  
MMP1    
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Top MMP1 Proteine auf antikoerper-online.de

Showing 10 out of 55 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Human Cells Human His tag 10 μg Anmelden zum Anzeigen 14 bis 16 Tage
$272.80
Details
HEK-293 Cells Human His tag 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$920.00
Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
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Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
$5,370.21
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HEK-293 Cells Human His tag Validation with Western Blot 10 μg Anmelden zum Anzeigen 4 bis 8 Tage
$242.00
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Escherichia coli (E. coli) Human Unkonjugiert Validation with Western Blot 10 μg Anmelden zum Anzeigen 4 bis 8 Tage
$218.90
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Human Human Unkonjugiert 10 μg Anmelden zum Anzeigen 6 bis 7 Tage
$474.41
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HEK-293 Cells Human His tag Validation with Western Blot 10 μg Anmelden zum Anzeigen 4 bis 8 Tage
$504.90
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Human Cells Human His tag   50 μg Anmelden zum Anzeigen 4 Days
$522.50
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Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$400.00
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MMP1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , ,
, ,
Rat (Rattus)

Mouse (Murine)

Am meisten referenzierte MMP1 Proteine

  1. Human MMP1 Protein expressed in Human Cells - ABIN2003013 : Desrochers, Jeffrey, Weiss: Interstitial collagenase (matrix metalloproteinase-1) expresses serpinase activity. in The Journal of clinical investigation 1991 (PubMed)
    Show all 5 Pubmed References

Weitere Proteine zu Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Interaktionspartnern

Human Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Interaktionspartner

  1. High MMP1 expression is associated with severe degenerative disc.

  2. MMP-1 and MMP-8 gene polymorphisms have a role in promoting the increase and remodeling of the collagen III and V in posterior tibial tendinopathy

  3. For MMP-1(-1607) 1G/2G, a significant association was observed using the recessive genetic model. In the subgroup studies, a significant association was observed in the Asian subgroup (OR = 1.68; for the recessive model; and OR = 1.59; for the allelic contrast model) and in the European subgroup (OR = 0.65; for the allelic contrast model).

  4. rs1799750 in MMP1 might be a risk factor for rheumatic heart disease in a Han population in Southern China, and individuals carrying the 2G/2G genotype are likely more susceptible to rheumatic heart disease.

  5. RHCG Suppresses Tumorigenicity and Metastasis in Esophageal Squamous Cell Carcinoma via Inhibiting NF-kappaB Signaling and MMP1 Expression.

  6. Malignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer.

  7. Data suggest that matrix metalloproteinase-1 and neutrophil elastase may be important but heretofore unrecognized players in stimulating uterine contractions at the time of labor, and they may explain why indomethacin delays, but does not prevent, preterm labor because indomethacin inhibits the prostaglandin component but not the protease component of labor.

  8. the present study demonstrated that scopoletin inhibited MMP1 and proinflammatory cytokine expression by inhibiting p38 MAPK phosphorylation.

  9. Matrix metalloproteinase 1(MMP1), which was downregulated in myelodysplastic syndromes (MDS)-mesenchymal stromal cells (MSCs), was identified as an inhibitory factor of MDS cell proliferation.

  10. study to explore the relationship between 2 polymorphisms (MMP-1-755 T/G [rs498186] and MMP-3 A/C [rs632478]) and disc degeneration; no significant association of the MMP-1 polymorphism with disc degeneration was found

  11. Expression of GSDMC is increased by UV irradiation in human skin keratinocytes. GSDMC induction contributes to the increase of MMP-1 expression specifically via activation of ERK and JNK pathways.

  12. our results suggest that the typical 1G/2G MMP-1 polymorphic site did not play a direct determinant role in breast cancer among Taiwanese women.

  13. The maternal and fetal 1G/1G MMP1 gene polymorphisms may be strong genetic markers of preeclampsia, occurring either individually or together.

  14. The current study indicated that MMP1 has a key role in the regulation of cervical tumor growth and lymph node metastasis via epithelial mesenchymal transition to a certain extent

  15. 2G allele of MMP-1, C allele of MMP-2 and 5A/6A genotype of MMP-3 are associated with susceptibility and disease progression of type 2 diabetic nephropathy

  16. this study provides insights into the development of a possible alternative therapy manipulating MMP-1 and the mTOR signaling pathway in Epidermal growth factor receptor-tyrosine kinase inhibitor-resistant lung adenocarcinoma.

  17. Specific silencing that targeted AMPK resulted in the enhancement of mobility and contractility and in the production of MMP-1 and MMP-2.

  18. MMP-1 genotype may accelerate the development of HIV-associated neurocognitive disorder (HAND) whereas MMP3 -1612 5A5A genotype may reduce the risk of pathogenesis of HAND.

  19. Authors observed a significant increase in the immunoexpression of collagen I and III in patients with DCM and a significant reduction in the immunoexpression of MMP-1 compared with the control group. Also, the collagen I and TIMP-1 expression indicated a positive linear correlation and respectively a negative linear relationship with collagen III and MMP-1.

  20. findings suggest that the polymorphic genotypes at MMP-1 promoter -1607 may play a major role in determining personal cancer susceptibility for prostate cancer in Taiwan

Pig (Porcine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Interaktionspartner

  1. the identification of MMP1 and MMP10 genes in swine is reported.

  2. increased interstitial MMP1 activity during ischemia and reperfusion is a result of the endothelin protein kinase c pathway and may be due to enhanced phosphorylation of mmp1

  3. Results indicate that leukemia inhibitory factor (LIF) and Oncostatin M increase the expression of MMP-1, MMP-3, and TIMP-1 several fold, and that their expression is reduced to basal levels in the presence of the LIF antagonist MH35-BD.

Fruit Fly (Drosophila melanogaster) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Interaktionspartner

  1. there are only two MMP genes in Drosophila, DmMmp1 and DmMmp2, which makes Drosophila an attractive system to analyze the basis of MMP specificity. Previously, Drosophila MMPs have been categorized by their pericellular localization, as Mmp1 appeared to be secreted and Mmp2 appeared to be membrane-anchored, suggesting that protein localization was the critical distinction in this small MMP family

  2. results suggest that Ubx regulates organ shape by controlling Mmp1 expression, and the extent and timing of extracellular matrix degradation.

  3. This work identifies Draper-dependent activation of MMP-1 as a novel cascade required for proper glial clearance of severed axons.

  4. Mmp1 negatively regulates ectopic eye differentiation by restricting the rate of proliferation and the levels of expression of retinal-determining genes dachshund and eyes absent.

  5. Data indicate that matrix metalloproteinases mmp1 and mmp2 mutants have distinct heart phenotypes.

  6. These data demonstrate that Mmp1 modulates PDF processing, which leads to daily structural remodeling and circadian behavior.

  7. A primary function of Mmp1, under the control of the JNK pathway, is to promote basement membrane repair, which in turn may permit cell migration and the restoration of a continuous tissue.

  8. Drosophila Mmp1 is involved in the regulation of ISC proliferation for maintenance of gut homeostasis

  9. Drosophila matrix metalloproteinases are required for tissue remodeling, but not embryonic development.

  10. MMP activity is essential for embryonic motor axon fasciculation

  11. Study identified three genes, regeneration (rgn), augmenter of liver regeneration (alr) and Matrix metalloproteinase-1 (Mmp1) expressed specifically in blastema cells during disc regeneration.

Cow (Bovine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Interaktionspartner

  1. BoHV-4 infection affects various pathways related to cell proliferation and cell surface integrity, at least three of which were centered on upregulation of matrix metalloproteinase 1 (MMP1). MMP1 transcription was upregulated by the BoHV-4 transactivator IE2/RTA, leading to abnormally high metalloproteinase tissue levels, potentially leading to defective endometrium healing and unresolved inflammation.

  2. The expression patterns of MMP1, MMP2, and MMP8 were explored during fetal and postnatal development of longissimus dorsi muscle in cattle, and the relationships of MMP1, MMP2, and MMP8 expression levels with meat quality traits were analyzed in cattle. The expression of MMP1, MMP2, and MMP8 were also tested in four kinds of fat tissues and three kinds of skeletal muscle tissues.

  3. Data suggest that luteolytic factors (such as interferon gamma, tumor necrosis factor alpha, and PGF2a) control expression of MMP1, other matrix metalloproteinases, and tissue inhibitors of metalloproteinase in cultured luteal cells.

  4. The results showed that a decrease in MMP-1 and MMP-2 gene expression is accompanied with a decrease in NO concentrations in infertile cows affected with ovarian cysts.

  5. Cytoskeletal tension modulates MMP-1 gene expression from tenocytes on micropillar substrates.

  6. MMP-1 promotes VEGFR2 expression and proliferation of endothelial cells through stimulation of PAR-1 and activation of NF-kappaB

  7. These data identify atypical PKC isozymes as STAT and ERK activators that mediate c-fos and collagenase expression.

  8. the differential expression and localization of membrane-type 1 matrix metalloproteinase in the corpus luteum suggest that it may have multiple functions throughout the course of the estrous cycle,including activation of pro-MMP-2

  9. increased in bovine preovulatory follicles following the gonadotropin surge but no up-regulation of MMP-1 and MMP-13 (follicular apex vs. base) for the preovulatory collagenolysis required for follicle rupture

  10. identification of MT1-MMP in odontoclasts during deciduous tooth resorption might be relevant to the migration activity that these cells have to gain access to the root surface

  11. MT1-MMP has a role in signaling events mediating EGFR transactivation

  12. IL-4 and IL-13 affect airway smooth muscle (SM) gel contraction via a phosphatidylinositol 3-kinase mediated endogenous production of MMP-1 that alters the interaction between SM cells and collagen fibers.

  13. In cervix, MMP1 is only active during the final cervical ripening process at parturition.

Rabbit Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Interaktionspartner

  1. These results suggest that PEP-1-SIRT2 promotes matrix metalloproteinases-induced dedifferentiation via ERK signaling in articular chondrocytes. .

  2. the total content and active forms of matrix metalloproteinases (MMPs)-1, -3, and -13 was measured to assess the potential role of the mechanical environment in regulation of matrix turnover by ligament fibroblasts.

  3. Circulating smoke components, including acrolein, contribute to vascular diseases through enhanced MMP-1 and decreased TIMP-3 secretion.

Horse (Equine) Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Interaktionspartner

  1. ANXA2 and MMP1 might participate in remodeling during wound healing in the horse.

  2. The polymorphism in the promoter of the MMP-1 gene could be a risk factor for early implant failure of total hip arthroplasty.

  3. These results suggest that MMP-1 and IL-8 are both involved in the exercise-induced stress response, and this represents a starting point from which to understand the adaptive responses to this phenomenon.

Xenopus laevis Matrix Metallopeptidase 1 (Interstitial Collagenase) (MMP1) Interaktionspartner

  1. matrix metalloproteinases 7, 9, and 18 are required in vivo for macrophage migration during embryonic development

MMP1 Protein Überblick

Protein Überblick

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes a secreted enzyme which breaks down the interstitial collagens, types I, II, and III. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit MMP1

  • matrix metallopeptidase 1 (MMP1)
  • Matrix metalloproteinase 1 (Mmp1)
  • matrix metalloproteinase 1 (RB11133)
  • matrix metalloproteinase 1 (Mmp1)
  • matrix metallopeptidase 1 (interstitial collagenase) (MMP1)
  • matrix metallopeptidase 1 S homeolog (mmp1.S)
  • interstitial collagenase (LOC100727966)
  • matrix metallopeptidase 1 (Mmp1)
  • CG4859 Protein
  • CLG Protein
  • Clgn Protein
  • col4 Protein
  • dm1-MMP Protein
  • Dmel\\CG4859 Protein
  • dmmp1 Protein
  • l(2)k04809 Protein
  • MMP-1 Protein
  • Mmp1 Protein
  • Mmp 1 Protein
  • Mmp1a Protein
  • mmp18 Protein

Bezeichner auf Proteinebene für MMP1

fibroblast collagenase , interstitial collagenase , matrix metalloprotease 1 , matrix metalloproteinase 1 , MMP-1 , matrix metalloproteinase 1 (type I collagenase) , matrix metalloproteinase-1 , CG4859-PC , CG4859-PD , CG4859-PE , CG4859-PF , CG4859-PG , CG4859-PH , CG4859-PI , CG4859-PJ , CG4859-PK , CG4859-PL , Mmp1-PC , Mmp1-PD , Mmp1-PE , Mmp1-PF , Mmp1-PG , Mmp1-PH , Mmp1-PI , Mmp1-PJ , Mmp1-PK , Mmp1-PL , collagenase-1 , MMP-18 , collagenase-4 , matrix metalloproteinase-18 , xCol4 , matrix metallopeptidase 1a , matrix metalloproteinase 1a (interstitial collagenase) , myocardial collagenase

GENE ID SPEZIES
4312 Homo sapiens
397320 Sus scrofa
37949 Drosophila melanogaster
1790862 Rhodopirellula baltica SH 1
100144547 Bombyx mori
281308 Bos taurus
100009110 Oryctolagus cuniculus
489428 Canis lupus familiaris
100033896 Equus caballus
495287 Xenopus laevis
101120355 Ovis aries
100727966 Cavia porcellus
300339 Rattus norvegicus
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