anti-Leukocyte Cell Derived Chemotaxin 1 (LECT1) Antikörper

LECT1 encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. Zusätzlich bieten wir Ihnen Leukocyte Cell Derived Chemotaxin 1 Kits (20) und Leukocyte Cell Derived Chemotaxin 1 Proteine (13) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
LECT1 11061 O75829
LECT1 16840 Q9Z1F6
LECT1 81512 O70367
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Top anti-Leukocyte Cell Derived Chemotaxin 1 Antikörper auf antikoerper-online.de

Showing 10 out of 39 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-LECT1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  721_B cell lysate LECT1 is supported by BioGPS gene expression data to be expressed in 721_B Host:  Rabbit  Target Name:  LECT1  Sample Tissue:  Human 786-0  Antibody Dilution:  1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with LECT1 antibody (C-term) (ABIN389196), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis of anti-LECT1 Antibody (C-term) (ABIN389196) in NCI-H460 cell line lysates (35 µg/lane).LECT1(arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ICC, IHC, WB Western Blot; Sample: Mouse Heart lysate; Primary Ab: 5µg/ml Rabbit Anti-Human LECT1 Antibody Second Ab: 0.2µg/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody (Catalog: SAA544Rb19) 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$350.00
Details
Human Kaninchen Unkonjugiert IP, WB Immunoprecipitation of LECT1 transfected lysate using anti-LECT1 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with LECT1 purified MaxPab mouse polyclonal antibody (B01P) . Western Blot analysis of LECT1 expression in transfected 293T cell line by LECT1 MaxPab polyclonal antibody.<br><br>Lane 1: LECT1 transfected lysate(37.10 KDa).<br>Lane 2: Non-transfected lysate.<br> 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$425.71
Details
Human Maus Unkonjugiert WB Western Blot analysis of LECT1 expression in transfected 293T cell line by LECT1 MaxPab polyclonal antibody.<br><br>Lane 1: LECT1 transfected lysate(36.74 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert ELISA, WB 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$446.88
Details
Human Kaninchen Unkonjugiert WB Western Blot: Chondromodulin-1/LECT1 Antibody [NBP1-59348] - 721_B cell lysate, concentration 0.2-1 ug/ml. Western Blot: Chondromodulin-1/LECT1 Antibody [NBP1-59348] - Sample Tissue: Human 786-0 Antibody Dilution: 1.0 ug/ml 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
$485.88
Details
Human Kaninchen Unkonjugiert ELISA, WB   200 μL Anmelden zum Anzeigen 16 Days
$221.38
Details

LECT1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Human , , ,
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Mouse (Murine)


Rat (Rattus)


Am meisten referenzierte anti-Leukocyte Cell Derived Chemotaxin 1 Antikörper

  1. Human Polyclonal LECT1 Primary Antibody für WB - ABIN4892235 : Lin, Wang, Wang: Chondromodulin‑I suppresses tumorigenesis of human osteosarcoma cells. in Molecular medicine reports 1970 (PubMed)

Weitere Antikörper gegen Leukocyte Cell Derived Chemotaxin 1 Interaktionspartner

Rabbit Leukocyte Cell Derived Chemotaxin 1 (LECT1) Interaktionspartner

  1. Chm-1 gene-modified bone marrow mesenchymal stem cells maintain the chondrogenic phenotype of tissue-engineered cartilage that can be used in cartilage tissue engineering.

Human Leukocyte Cell Derived Chemotaxin 1 (LECT1) Interaktionspartner

  1. ChMI directly suppressed the proliferation and growth of osteosarcoma cells.

  2. CHM1 seems to have pleiotropic functions in Ewing sarcoma.

  3. The results of the present study indicated that ChMI was able to inhibit the growth of breast cancer cells; thus suggesting that ChM-I may have potential clinical applications in the treatment of breast cancer.

  4. Data suggest ChM1 as potential tumor suppressor in gastric cancer and useful biomarker for the treatment and prognosis. Its expression was downregulated in cancer tissue, and correlated with advanced stages, lymph node metastasis, and poorer prognosis.

  5. intact 20-25 kDa ChM-I is stored as a component of extracellular matrix in the avascular cartilage zones, but it is inactivated by a single N-terminal proteolytic cleavage in the hypertrophic zone of growth-plate cartilage

  6. the inner meniscus contained larger amounts of ChM-I, and that the inner meniscus-derived ChM-I inhibited endothelial cell proliferation.

  7. Degenerative intervertebral disc cells express ChM-I. Administration of bFGF (zeige FGF2 Antikörper) down-regulates the expression of ChM-I. Expression is correlated with the degree of degeneration.

  8. Inhibition of YY1 (zeige YY1 Antikörper) in combination with forced expression of p300 (zeige EP300 Antikörper) and Sp3 (zeige SP3 Antikörper) restored the expression of ChM-I in cells with a hypomethylated promoter region, but not in cells with hypermethylation.

  9. Data suggest that chondromodulin-I impairs the VEGF-A (zeige VEGFA Antikörper)-stimulated motility of endothelial cells by destabilizing lamellipodial extensions.

  10. Methylation in the core-promoter region of the chondromodulin-I gene determines the cell-specific expression by regulating the binding of transcriptional activator Sp3 (zeige SP3 Antikörper)

Mouse (Murine) Leukocyte Cell Derived Chemotaxin 1 (LECT1) Interaktionspartner

  1. These findings indicated that Chm-I was an indispensable factor for ectopic cartilage regeneration and the maintenance of cartilage homeostasis.

  2. intact 20-25 kDa ChM-I is stored as a component of extracellular matrix in the avascular cartilage zones, but it is inactivated by a single N-terminal proteolytic cleavage in the hypertrophic zone of growth-plate cartilage

  3. the inhibitory action of ChM-I on trophoblast migration and invasion, implying the potential role of the ChM-I expression in decidual cells for the regulated tissue remodeling and angiogenesis at feto-maternal interface.

  4. chondromodulin 1 stabilizes the chondrocyte phenotype by supporting chondrogenesis but inhibiting chondrocyte hypertrophy and endochondral ossification.

  5. Role of ChM-I in cartilage and eye development

  6. chondromodulin I is a bone remodeling factor

  7. Chondromodulin I suppresses T cell responses and synovial cell proliferation, implying that this cartilage matrix protein (zeige MATN1 Antikörper) has a therapeutic potential in rheumatoid arthritis.

  8. chondromodulin-I has a pivotal role in maintaining valvular normal function by preventing angiogenesis that may lead to valvular heart diseases

  9. The expression domains of ChM-I and TeM (zeige TNMD Antikörper) during vertebrate development incorporate the typical avascular regions of the mesenchymal tissues.

  10. results suggest that Chm-I is involved in hypertrophic maturation of periosteal chondrocytes. Although a direct effect of Chm-I on bones is still unclear, bony callus formation was increased while external cartilaginous callus decreased in Chm1(-/-) mice

Leukocyte Cell Derived Chemotaxin 1 (LECT1) Antigen-Profil

Protein Überblick

This gene encodes a glycosylated transmembrane protein that is cleaved to form a mature, secreted protein. The N-terminus of the precursor protein shares characteristics with other surfactant proteins and is sometimes called chondrosurfactant protein although no biological activity has yet been defined for it. The C-terminus of the precursor protein contains a 25 kDa mature protein called leukocyte cell-derived chemotaxin-1 or chondromodulin-1. The mature protein promotes chondrocyte growth and inhibits angiogenesis. This gene is expressed in the avascular zone of prehypertrophic cartilage and its expression decreases during chondrocyte hypertrophy and vascular invasion. The mature protein likely plays a role in endochondral bone development by permitting cartilaginous anlagen to be vascularized and replaced by bone. It may be involved also in the broad control of tissue vascularization during development. Alternative splicing results in multiple transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit LECT1

  • chondromodulin L homeolog (cnmd.L) Antikörper
  • leukocyte cell derived chemotaxin 1 (lect1) Antikörper
  • chondromodulin (CNMD) Antikörper
  • chondromodulin (cnmd) Antikörper
  • chondromodulin (Cnmd) Antikörper
  • Bricd3 Antikörper
  • Chm-1 Antikörper
  • ChM-I Antikörper
  • CHM1 Antikörper
  • chondromodulin-I Antikörper
  • Lect1 Antikörper
  • MGC53801 Antikörper
  • MGC82444 Antikörper
  • MYETS1 Antikörper

Bezeichner auf Proteinebene für LECT1

leukocyte cell derived chemotaxin 1 , chondromodulin-I , chondromodulin-1-like , chondromodulin-1 , leukocyte cell-derived chemotaxin 1 , BRICHOS domain containing 3 , chondromodulin I , multiple myeloma tumor suppressor 1 , SCGP , small cartilage-derived glycoprotein , Chondromodulin 1 , chM-I

GENE ID SPEZIES
379773 Xenopus laevis
446632 Xenopus laevis
694189 Macaca mulatta
735744 Pan troglodytes
100037893 Xenopus (Silurana) tropicalis
100226280 Taeniopygia guttata
100408687 Callithrix jacchus
100455694 Pongo abelii
100008692 Oryctolagus cuniculus
11061 Homo sapiens
395600 Gallus gallus
281683 Bos taurus
16840 Mus musculus
81512 Rattus norvegicus
609613 Canis lupus familiaris
100734572 Cavia porcellus
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