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May be involved in centriole formation or stability (By similarity)..
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Study shows that the interaction between Cep295 and Cep192 seems to be crucial for the integrity of centriole structure and also for daughter-to-mother centriole conversion.
our results indicate that CEP295 directly interacts with microtubules, and that excess CEP295 could induce the assembly of overly long centrioles. Furthermore, exogenous expression of the N-terminal domain of CEP295 exerts a dominant-negative effect on centriole elongation. Collectively, these findings suggest that CEP295 is essential for building the distal half centrioles and for post-translational modification of centr
A newborn centriole-enriched protein, KIAA1731/CEP295, specifically mediates centriole-to-centrosome conversion but dispensable for cartwheel removal.
data suggest centrosomal functions for C10orf90 and KIAA1731 and new centriole-related functions for ALMS1.
May be involved in centriole formation or stability (By similarity).
centrosomal protein KIAA1731
, centrosomal protein KIAA1731 homolog
, KIAA1731-like protein