anti-KIAA1549 (KIAA1549) Antikörper

The protein encoded by KIAA1549 belongs to the UPF0606 family.

Alle Antikörper anzeigen Gen GeneID UniProt
KIAA1549 57670 Q9HCM3
KIAA1549 330286 Q68FD9
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Top anti-KIAA1549 Antikörper auf

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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-KIAA1549 Antibody   Titration: 1.0 ug/ml   Positive Control: HepG2 Whole Cell Lanes:   Lane1-4: 30ug mouse neurosphere lysate  Primary Antibody Dilution:   1:1000  Secondary Antibody:   Anti-rabbit HRP  Secondary Antibody Dilution:   1:5000  Gene Name:   KIAA1549  Submitted by:   Yi-Hsien Chen, Washington University School of Medicine 100 μL 2 bis 3 Tage
Human Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
Maus Kaninchen Unkonjugiert WB   50 μg 11 bis 12 Tage

Weitere Antikörper gegen KIAA1549 Interaktionspartner

Human KIAA1549 Interaktionspartner

  1. these results demonstrate that f-BRAF expression creates a supportive tumor microenvironment through NFkappaB-mediated Ccl2 production and microglia recruitment.

  2. This study demonstrated that when whole chromosome 7 gain accompanies the KIAA1549-BRAF fusion, the fusion likely arises first.

  3. Mutations in BRAF-KIAA1549 were associated with central nervous system tumors.

  4. This study confirmed the high frequency of KIAA1549:BRAF fusion in Pilocytic Astrocytomas.

  5. Pediatric oligodendrogliomas (pODGs) can harbor the KIAA1549-BRAF fusion with aberrant MAPK/ERK signaling, and there exists an option of targeting these pathways in such patients.

  6. we identify KIAA1549-BRAF gene fusions in 45 % of 82 low-grade glioma samples

  7. Molecular genetic analysis revealed BRAF duplication and a KIAA1549-BRAF fusion gene in 82% of group II tumors, but in none of the group I tumors, and a BRAF:p.V600E mutation in 43% of group I tumors, but in none of the group II tumors.

  8. Our results suggest that in a small fraction of diffuse gliomas, KIAA1549-BRAF fusion gene and BRAF(v600E) mutation may be responsible for deregulation of the Ras-RAF-ERK signaling pathway

  9. we found no cases of Rosette-forming glioneuronal tumors of the fourth ventricle showing KIAA1549-BRAF gene fusion or BRAF (V600E) mutation

  10. The frequency of BRAF-KIAA1549 fusion transcripts is significantly lower in adult patients with pilocytic astrocytoma.

  11. KIAA1549:BRAF fusions predominate in pilocytic astrocytomas but are also present in some low-grade unclassifiable gliomas and glioneuronal tumors.

  12. KIAA1549 is a target gene of the BACH1 transcription factor according to ChIP-seq analysis in HEK 293 cells.

KIAA1549 Antigen-Profil

Protein Überblick

The protein encoded by this gene belongs to the UPF0606 family. This gene has been found to be fused to the BRAF oncogene in many cases of pilocytic astrocytoma. The fusion results from 2Mb tandem duplications at 7q34. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit anti-KIAA1549 (KIAA1549) Antikörper

  • KIAA1549 (KIAA1549) Antikörper
  • RIKEN cDNA D630045J12 gene (D630045J12Rik) Antikörper
  • Kiaa1549 Antikörper
  • mKIAA1549 Antikörper

Bezeichner auf Proteinebene für anti-KIAA1549 (KIAA1549) Antikörper

UPF0606 protein KIAA1549

57670 Homo sapiens
330286 Mus musculus
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