Interleukin 32 Proteine (IL32)

IL32 encodes a member of the cytokine family. Zusätzlich bieten wir Ihnen IL32 Antikörper (154) und IL32 Kits (42) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
IL32 9235 P24001
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Human Cells Human His tag 100 μg Anmelden zum Anzeigen 20 bis 21 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 15 bis 19 Tage
Escherichia coli (E. coli) Human His tag   1 mg Anmelden zum Anzeigen 2 bis 3 Tage
Escherichia coli (E. coli) Human Unkonjugiert   5 applications Anmelden zum Anzeigen 1 bis 2 Tage
Escherichia coli (E. coli) Human Unkonjugiert   10 μg Anmelden zum Anzeigen 11 bis 12 Tage

IL32 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, ,
Mouse (Murine)
Rat (Rattus)

Weitere Proteine zu Interleukin 32 (IL32) Interaktionspartnern

Human Interleukin 32 (IL32) Interaktionspartner

  1. Strong expression of IL-32 was detected in cardiomyocytes from heart failure patients.

  2. The increase in serum levels of IL-32 in accordance with additive effect of the presence of C allele in Multiple sclerosis patients might introduce IL-32 as a key player in MS pathogenesis or immunedysregulation

  3. Collectively, these results demonstrated that IL-32alpha upregulates the atheroprotective genes Timp3 (zeige TIMP3 Proteine) and Reck (zeige RECK Proteine) by downregulating microRNA-205 through regulation of the Rprd2-Dgcr8 (zeige DGCR8 Proteine)/Ddx5 (zeige DDX5 Proteine)-Dicer1 (zeige DICER1 Proteine) biogenesis pathway.

  4. high expression of both IL17A (zeige IL17A Proteine) and IL32 leads to enhancement of T cell responses in breast tumors

  5. High IL32 expression is associated with lung metastasis in melanoma.

  6. In Kaposi sarcoma (KS) splicing ratio of the IL-32 isoforms showed IL-32gamma as the highest expressed isoform, followed by IL-32beta, in HIV-related KS cases compared with controls. Our data suggest a possible survival mechanism by the splicing of IL-32gamma to IL-32beta and also IL-6 (zeige IL6 Proteine), IL-8 (zeige IL8 Proteine), and CXCR1 (zeige CXCR1 Proteine) signaling pathways to reverse the proapoptotic effect of the IL-32gamma isoform, leading to tumor cell survival and th...

  7. Three single nucleotide polymorphisms (SNPs) (rs28372698, rs12934561, rs4786370) of the IL32 gene have been proposed as modifiers for different diseases. The present study found no significant differences in the genotypic frequencies between the patients and healthy controls and no relation to survival for any of the SNPs.

  8. This study showed that the induction level of IL-32 was increased in chronic rhinosinusitis with nasal polyps compared to normal nasal mucosa and that LPS (zeige IRF6 Proteine)-induced IL-32 expression in nasal polyp-derived fibroblasts was regulated via the TLR4 (zeige TLR4 Proteine)/JNK (zeige MAPK8 Proteine)/AKT (zeige AKT1 Proteine)/CREB (zeige CREB1 Proteine) signaling pathway.

  9. findings show that IL-32alpha acts on NK cells to inhibit IL-15 (zeige IL15 Proteine)-mediated STAT5 (zeige STAT5A Proteine) phosphorylation and to suppress their IL-15 (zeige IL15 Proteine)-induced effector molecule expression and cytolytic capacity. IL-32alpha also acted on DCs by downregulating IL-15 (zeige IL15 Proteine)-induced IL-18 (zeige IL18 Proteine) production, an important cytokine in NK cell activity.

  10. Thus, endogenous IL-32 is a crucial cytokine involved in the host defense against Leishmania parasites.

IL32 Protein Überblick

Protein Überblick

This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Genbezeichner und Symbole assoziert mit Interleukin 32 Proteine (IL32)

  • interleukin 32 (IL32)
  • IL-32alpha Protein
  • IL-32beta Protein
  • IL-32delta Protein
  • IL-32gamma Protein
  • NK4 Protein
  • TAIF Protein
  • TAIFa Protein
  • TAIFb Protein
  • TAIFc Protein
  • TAIFd Protein

Bezeichner auf Proteinebene für Interleukin 32 Proteine (IL32)

interleukin-32 , interleukin-32 eta , interleukin-32 small , interleukin-32 theta , natural killer cell transcript 4 , natural killer cells protein 4 , tumor necrosis factor alpha-inducing factor

9235 Homo sapiens
505800 Bos taurus
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