anti-Interleukin 13 Receptor, alpha 2 (IL13RA2) Antikörper

The protein encoded by IL13RA2 is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. Zusätzlich bieten wir Ihnen IL13RA2 Kits (33) und IL13RA2 Proteine (30) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
IL13RA2 3598 Q14627
IL13RA2 16165 O88786
IL13RA2 171060  
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Top anti-IL13RA2 Antikörper auf antikoerper-online.de

Showing 10 out of 132 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert BR, CyTOF, FACS, IHC, SimWes, WB 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$441.83
Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-IL13RA2 Antibody Titration: 0.2-1 ug/mlPositive Control: HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-IL13RA2 Antibody Titration: 0.2-1 ug/mlPositive Control: MCF7 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
Details
Human Maus Unkonjugiert Func, IHC (fro), FACS, IHC (p) 0.2 mg Anmelden zum Anzeigen 6 bis 8 Tage
$308.00
Details
Human Maus Unkonjugiert IHC (fro), FACS, IHC (p) A typical staining pattern with the B-D13 monoclonal antibody of IL-13Ra2 transfected CHO cell line 200 μL Anmelden zum Anzeigen 6 Days
$323.68
Details
Ratte Kaninchen Unkonjugiert ELISA, IHC (p) Immunochemical staining of rat IL13RA2 in rat brain with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). Immunochemical staining of rat IL13RA2 in rat liver with rabbit polyclonal antibody (1 µg/mL, formalin-fixed paraffin embedded sections). 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$218.90
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$429.84
Details
Human Kaninchen Unkonjugiert WB   200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Maus Unkonjugiert ELISA, WB Western Blot analysis of IL13RA2 expression in transfected 293T cell line by IL13RA2 monoclonal antibody (M01), clone 2E10. Lane 1: IL13RA2 transfected lysate(44.176 KDa). Lane 2: Non-transfected lysate. Western blot analysis of IL13RA2 over-expressed 293 cell line, cotransfected with IL13RA2 Validated Chimera RNAi used as specificity and loading control. 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$527.50
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details

Am meisten referenzierte anti-IL13RA2 Antikörper

  1. Human Polyclonal IL13RA2 Primary Antibody für BR, CyTOF - ABIN5012923 : Trieu, Wen, Skinnider, Bray, Li, Claudio, Masih-Khan, Zhu, Trudel, McCart, Mak, Stewart: Soluble interleukin-13Ralpha2 decoy receptor inhibits Hodgkin's lymphoma growth in vitro and in vivo. in Cancer research 2004 (PubMed)
    Show all 18 Pubmed References

  2. Human Monoclonal IL13RA2 Primary Antibody für IHC (fro), FACS - ABIN1383686 : Joshi, Plautz, Puri: Interleukin-13 receptor alpha chain: a novel tumor-associated transmembrane protein in primary explants of human malignant gliomas. in Cancer research 2000 (PubMed)
    Show all 8 Pubmed References

  3. Human Polyclonal IL13RA2 Primary Antibody für FACS - ABIN4896504 : Biancheri, Di Sabatino, Ammoscato, Facciotti, Caprioli, Curciarello, Hoque, Ghanbari, Joe-Njoku, Giuffrida, Rovedatti, Geginat, Corazza, MacDonald: Absence of a role for interleukin-13 in inflammatory bowel disease. in European journal of immunology 2014 (PubMed)

  4. Human Monoclonal IL13RA2 Primary Antibody für RNAi, ELISA - ABIN561476 : Zeis, Graumann, Reynolds, Schaeren-Wiemers: Normal-appearing white matter in multiple sclerosis is in a subtle balance between inflammation and neuroprotection. in Brain : a journal of neurology 2007 (PubMed)

Weitere Antikörper gegen IL13RA2 Interaktionspartner

Human Interleukin 13 Receptor, alpha 2 (IL13RA2) Interaktionspartner

  1. this study shows that tricellulin is regulated via interleukin-13-receptor alpha2, affects macromolecule uptake, and is decreased in ulcerative colitis

  2. IL-13Ralpha2 alone induces invasiveness of human glioblastoma multiforme (GBM) cells without affecting their proliferation. In contrast, in the presence of the mutant EGFR (EGFRvIII), IL-13Ralpha2 promotes GBM cell proliferation in vitro and in vivo.

  3. The results showed that IL13Ralpha2 may be used as a marker of poorer prognosis in high-grade astrocytomas, even among tumors of the same grade.

  4. TMEM219 plays a critical role in Chi3l1-induced IL-13Ralpha2 mediated signalling and tissue responses.

  5. This study shows interleukin-13 receptor alpha 2 expression could be a useful prognostic marker for selecting patients with luminal breast cancer likely to follow a clinically aggressive course despite receiving systemic therapy.

  6. Transgenic expression of IL15 is an appealing strategy to enhance CAR T-cell effector function. We tested this approach in our IL13Ralpha2-positive glioma model in which limited IL13Ralpha2-CAR T-cell persistence results in recurrence of antigen-positive gliomas. T cells were genetically modified with retroviral vectors encoding IL13Ralpha2-CARs or IL15 (IL13Ralpha2-CAR.IL15 T cells).

  7. IL-13Ralpha2 may have a role in decreased overall survival in gastric cancer after gastrectomy

  8. cigarette smoke extracts activate the PKA, CREB, and IL-13Ralpha2 axis in lung endothelial cells.

  9. High expression of IL-13Ra2 is significantly associated with the growth and metastasis of glioma cells via the Scr/PI3K/Akt/mTOR pathway.

  10. A negative correlation between IL-13Ra2 and IL-13 was found during early infection of human schistosomiasis, suggesting an increase in cytokine in early fibrosis.

  11. Data indicate single-chain antibody (scFv47) as a highly selective interleukin 13 receptor subunit alpha 2 (IL13Ralpha2) targeting agent.

  12. IL13Ralpha2 knockdown and IL-13 treatment cooperatively upregulated the metastasis suppressor tumor protein 63 (TP63) in a STAT6-dependent manner.

  13. Expression of CXCR3 in fibroblasts is associated with the expression of IL-13Ralpha2.

  14. In this review, we will discuss the recent advances in the IL13Ralpha2-targeted immunotherapy and evaluate the most promising strategy for targeted GBM immunotherapy. [review]

  15. Study presents evidence that PNR could promote ERalpha-negative breast cancer metastasis through activation of IL-13Ralpha2-mediated signaling pathway.

  16. Results suggest that the physical interaction between the cytoplasmic domains of IL-13Ralpha2 and IL-4Ralpha regulates IL-4 signaling through the IL-4Ralpha-IL-13Ralpha1 receptor complex.

  17. In cytotoxicity assays, CAR T cells killed CAR T cells killed IL13Ra1- and/or IL13Ra2-positive cells in contrast to IL13Ra1- and IL13Ra2-negative controls

  18. IL13Ralpha2 over-expression is associated with glioma.

  19. endogenously expressed IL-13Ralpha2 does not activate any unique IL-13-mediated gene expression patterns, confirming its role as a decoy receptor for IL-13 signaling.

  20. Data suggest that the single nucleotide polymorphisms in IL-13/IL-13R genes do not have an impact on the risk of developing endemic PF in Tunisian population.

Mouse (Murine) Interleukin 13 Receptor, alpha 2 (IL13RA2) Interaktionspartner

  1. Upon lipopolysaccharide stimulation, macrophage Raw 264.7 cells showed elevated IL-13R-alpha-2 expression via immunofluorescence staining and increased MRI probe binding via built-in TAMRA fluorescence imaging. for the first time, IL-13R-alpha-2 was investigated as a unique biomarker in the context of osteomyelitis.

  2. Study presents evidence that PNR could promote ERalpha-negative breast cancer metastasis through activation of IL-13Ralpha2-mediated signaling pathway.

  3. overexpression of IL-13Ra2 inhibits the IL-13 induction of fibrotic markers in vitro and inhibits bleomycin-induced pulmonary fibrosis.

  4. data collectively support a distinct role for membrane IL-13Ralpha2 in the lung and suggest that memIL-13Ralpha2 might contribute to allergic inflammation

  5. IL-13 contributes to the development of pulmonary hypertension via an IL-13receptor alpha2-arginase 2-dependent pathway.

  6. When combined with IL-13Ralpha2 DNA cancer vaccine, Pseudomonas aeruginosa exotoxin A mediates synergistic antitumor effects on tumor growth and metastasis in established murine breast carcinoma and sarcoma tumor models.

  7. Colitis and intestinal inflammation in IL10(-/-) mice results from IL-13Ralpha2-mediated attenuation of IL-13 activity.

  8. IL-13Ralpha2 serves a protective role in the pathogenesis of allergic inflammation and loss of skin barrier function in a mouse model of atopic dermatitis.

  9. peaks of upregulation in allergic bronchial asthma at 6 hours and 3-12 hours after the last antigen inhalation

  10. studies illustrate the central role played by the IL-13Ralpha2 in the down-regulation of a chronic and pathogenic Th2-mediated immune response

  11. These results are consistent with a phenotype of enhanced interleukin-13 (IL-13)responsiveness and demonstrate a role for endogenous IL-13 and IL-13 alpha2 receptor in regulating immune responses in wild-type mice.

  12. IL-13 receptor alpha2

  13. by suppressing IFN-gamma and up-regulating the decoy IL-13 receptor, P-selectin dramatically inhibits the pathologic tissue remodeling that results from chronic type 2 cytokine-mediated hepatic inflammation

  14. TGF-beta1 production and fibrosis require IL-13 signaling through the IL-13alpha2 receptor

  15. IL-10 and IL-13Ralpha2 are both required to control chronic Th2-driven pathological responses.

  16. sIL-4Ralpha predominantly sustains, increases, and diffuses the effects of IL-4, whereas sIL-13Ralpha2 limits the direct effects of IL-13 to the site of IL-13 production and forms a stable complex with IL-13

  17. IL-13Ralpha2 is a selective and powerful inhibitor of IL-13-induced inflammatory, remodeling, and physiologic responses in the murine lung.

  18. Restoration of tumor immunosurveillance via targeting of interleukin-13 receptor-alpha 2.

  19. study concludes that matrix metalloproteinase-8 cleaves IL-13R alpha 2 in vitro and contributes to the solubilization of IL-13R alpha 2 in vivo

  20. Human and murine neuroendocrine pheochromocytoma overexpress the IL-13Ralpha2 chain, and an IL-13PE-based receptor-directed anticancer approach may prove useful in treatment for metastatic pheochromocytoma patients.

IL13RA2 Antigen-Profil

Protein Überblick

The protein encoded by this gene is closely related to Il13RA1, a subuint of the interleukin 13 receptor complex. This protein binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. It is reported to play a role in the internalization of IL13.

Genbezeichner und Symbole assoziert mit IL13RA2

  • interleukin 13 receptor, alpha 2 (il13ra2) Antikörper
  • interleukin 13 receptor subunit alpha 2 (IL13RA2) Antikörper
  • interleukin 13 receptor subunit alpha 2 S homeolog (il13ra2.S) Antikörper
  • interleukin 13 receptor, alpha 2 (Il13ra2) Antikörper
  • interleukin 13 receptor subunit alpha 2 (Il13ra2) Antikörper
  • CD213a2 Antikörper
  • CT19 Antikörper
  • IL-13R Antikörper
  • IL-13R-alpha-2 Antikörper
  • il-13ra2 Antikörper
  • IL13BP Antikörper
  • IL13RA2 Antikörper
  • sb:cb602 Antikörper
  • si:dkeyp-110c7.6 Antikörper

Bezeichner auf Proteinebene für IL13RA2

interleukin-13 receptor alpha 2 , interleukin-13 receptor subunit alpha-2 , IL-13 receptor alpha 2 , interleukin 13 receptor, alpha 2 , interleukin-13 receptor subunit alpha-2-like , IL-13 receptor subunit alpha-2 , IL-13R subunit alpha-2 , IL-13R-alpha-2 , IL-13RA2 , cancer/testis antigen 19 , interleukin 13 binding protein , interleukin 13 receptor alpha 2 chain , interleukin-13-binding protein , interleukin 13 receptor alpha chain 2

GENE ID SPEZIES
368326 Danio rerio
422219 Gallus gallus
465815 Pan troglodytes
495398 Xenopus laevis
100441311 Pongo abelii
100601369 Nomascus leucogenys
3598 Homo sapiens
403622 Canis lupus familiaris
16165 Mus musculus
171060 Rattus norvegicus
616008 Bos taurus
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