IQ Motif Containing GTPase Activating Protein 2 (IQGAP2) ELISA Kits

IQGAP2 encodes a member of the IQGAP family. Zusätzlich bieten wir Ihnen IQGAP2 Antikörper (61) und IQGAP2 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Ratte IQGAP2 IQGAP2 100360623  
IQGAP2 10788 Q13576
IQGAP2 544963 Q3UQ44
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Top IQGAP2 ELISA Kits auf

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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Lieferzeit Preis Details
Maus 0.062 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 bis 16 Tage
Human < 0.094 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 bis 18 Tage
Maus < 0.062 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests 11 bis 18 Tage

Weitere ELISA Kits für IQGAP2 Interaktionspartner

Xenopus laevis IQ Motif Containing GTPase Activating Protein 2 (IQGAP2) Interaktionspartner

  1. Suppression of XIQGAP2 expression caused ectodermal lesions in the neurula stage embryos.

Human IQ Motif Containing GTPase Activating Protein 2 (IQGAP2) Interaktionspartner

  1. Data suggest that CDC42 binding to Ex-domain of IQGAP2 releases Ex-domain at C-terminal region of GRD2 domain, facilitating IQGAP2 dimerization; this promotes allosteric changes in ras GTPase-activating protein binding site providing binding site for second CDC42; RAC1 binds only to apo-IQGAP2. (IQGAP2 = IQ motif containing GTPase activating protein-2; CDC42 = GTP-binding protein CDC42; RAC1 = Rac family small GTPase-1)

  2. IQGAP2 expression correlated positively with survivability, on the contrary, IQGAP3 expression levels correlated inversely with survivability

  3. The structural basis for Cdc42-induced dimerization of IQGAP1 and IQGAP2 has been uncovered.

  4. The most frequently identified and connected to preterm birth genes in the exome library were IGF1, ATM and IQGAP2.

  5. IQGAP2 TagSNP rs457717 (A/G) was not associated with Age-Related Hearing impairment in Han male Chinese population.

  6. Thus, these data identified IQGAP2 as a novel tumor suppressor for ovarian cancer to inhibit cell invasion through regulating Wnt/b-catenin signaling, and provided a new biomarker and potential therapeutic strategy for this disease.

  7. we identified IQGAP2 as a human and zebrafish podocyte gene product that is downregulated in microarray data sets from kidney biopsies of human patients with focal segmental glomerulosclerosis and minimal change nephrotic syndrome.

  8. Data show that IQ motif-containing GTPase-activating protein 2 (IQGAP2) expression is altered in colitis.

  9. IQGAP1, IQGAP2, and IQGAP3 have diverse roles in vertebrate physiology, operating in the kidney, nervous system, cardiovascular system, pancreas, and lung. (Review)

  10. Mammalian IQGAP proteins may play a role in cytokinesis by regulating the localization of key cytokinesis regulatory proteins to the contractile apparatus during mitosis.

  11. Low IQGAP2 expression was associated with hepatocellular carcinoma.

  12. The first IQ-motifs from IQGAP2 and IQGAP3 form transient interactions with calmodulin in the absence of calcium.

  13. observations strongly indicate that IQGAP2 is a surveillance type of tumour suppressor for prostate cancer

  14. increased IQGAP1 and/or decreased IQGAP2 contribute to the pathogenesis of human HCC.

  15. The top-ranked SNP, rs457717 for association with age-related hearing impairment(P-value 3.55 x 10(-7)), was localised in an intron of the IQ motif-containing GTPase-activating-like protein (IQGAP2).

  16. The gene for the putative rac1/cdc42 effector protein IQGAP2 was found in the PAR gene cluster at 5q13, flanked by PAR1 & encompassing PAR3. It functions as a GTP-dependent effector protein in thrombin-induced platelet cytoskeletal reorganization.

  17. silencing of IQGAP2 by promoter methylation may contribute to gastric cancer development.

Mouse (Murine) IQ Motif Containing GTPase Activating Protein 2 (IQGAP2) Interaktionspartner

  1. The exacerbated mast cell responses observed in the absence of Dnmt3a were recapitulated or enhanced by treatment with the demethylating agent 5-aza-2'-deoxycytidine as well as by down-modulation of Dnmt1 expression. These effects were in part mediated by the dysregulated expression of the scaffold protein IQGAP2.

  2. found a hypomethylated region mapping to Iqgap2 (IQ motif-containing GTPase activating protein 2) and F2rl2

  3. Data show that complete loss of IQ motif-containing GTPase-activating protein 2 (IQGAP2) gene leads to protection from dextran sulfate sodium (DSS)-induced colitis.

  4. Transcript profiling identifies iqgap2(-/-) mouse as a model for advanced human hepatocellular carcinoma.

  5. Phosphoinositide module is defined by a C-terminal 105-107 amino acid region of which IQGAP1 and -2, but not IQGAP3, binds preferentially to phosphatidylinositol 3,4,5-trisphosphate (PtdInsP(3)).

  6. murine IQGAP2 selectively regulates the facilitated phase of hepatic fatty acid uptake both in vitro and in vivo

  7. Development of hepatocellular carcinoma in Iqgap2-deficient mice is Iqgap1 dependent.

IQGAP2 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the IQGAP family. The protein contains three IQ domains, one calponin homology domain, one Ras-GAP domain and one WW domain. It interacts with components of the cytoskeleton, with cell adhesion molecules, and with several signaling molecules to regulate cell morphology and motility.

Genbezeichner und Symbole assoziert mit IQGAP2

  • IQ motif containing GTPase activating protein 2 S homeolog (iqgap2.S) Antikörper
  • IQ motif containing GTPase activating protein 2 (IQGAP2) Antikörper
  • IQ motif containing GTPase activating protein 2 (iqgap2) Antikörper
  • ras GTPase-activating-like protein IQGAP1 (LOC100168908) Antikörper
  • IQ motif containing GTPase activating protein 2 (Iqgap2) Antikörper
  • 4933417J23Rik Antikörper
  • A630053O10 Antikörper
  • AI788777 Antikörper
  • IQGAP2 Antikörper
  • XIQGAP2 Antikörper

Bezeichner auf Proteinebene für IQGAP2

IQ motif containing GTPase activating protein 2 , ras GTPase-activating-like protein IQGAP2-like , ras GTPase-activating-like protein IQGAP2

398588 Xenopus laevis
461801 Pan troglodytes
479177 Canis lupus familiaris
100124996 Xenopus (Silurana) tropicalis
100168908 Acyrthosiphon pisum
100360623 Rattus norvegicus
100400958 Callithrix jacchus
100446817 Pongo abelii
100519536 Sus scrofa
10788 Homo sapiens
544963 Mus musculus
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