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The protein encoded by GDF10 is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. Zusätzlich bieten wir Ihnen Growth Differentiation Factor 10 Antikörper (90) und Growth Differentiation Factor 10 Proteine (20) und viele weitere Produktgruppen zu diesem Protein an.
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Study shows that GDF10 is down-regulated in patients with oral squamous cell carcinoma, and is an independent risk factor for overall survival. Its expression is regulated by TGFBR3 which shares the signaling inhibiting epithelial-mesenchymal transition.
GDF10 is a stroke-induced signal for axonal sprouting and functional recovery.
new hypoxia-inducible and SOX9-regulated genes, Gdf10 and Chm-I. In addition, Mig6 and InhbA were induced by hypoxia, predominantly via HIF-2alpha
BMP3b and BMP6 genes were suppressed by DNA methylation and methylation of BMP3b is significantly frequent in Japanese malignant pleural mesotheliomas (MPMs), suggesting its pathogenic role and the ethnic difference in MPMs.
The caudo-ventral pallium is a novel pallial domain expressing Gdf10 and generating Ebf3-positive neurons of the medial amygdala.
Results show that Gdf10, expressed in Bergmann glial cells, is affected by the loss of Shh as early as E18.5, suggesting a regulation of glial development by Shh
Here we show that Runx2 is highly expressed in lung cancer cells and downregulates BMP-3B. The ectopic expression of Runx2, but not DNA binding mutant Runx2, in normal lung fibroblast cells and lung cancer cells resulted in suppression of BMP-3B levels.
data suggest that BMP-3b is secreted from adipocytes, is involved in adipocyte differentiation, and inhibits adipogenesis as a unique complex.
Sca-1 attenuated GDF10-dependent TGF-beta signaling by disrupting the heterodimerization of TbetaRI and TbetaRII receptors.
Gdf10 is expressed in Bergmann glia and is reduced in staggerer mice.
GDF10 gene might have potential effects on body measurement traits in the above mentioned cattle populations and could be used for marker-assisted selection.
The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice suggest that the protein encoded by this gene plays a role in skeletal morphogenesis.
growth differentiation factor 10
, bone morphogenetic protein 3B-like
, bone morphogenetic protein 3B
, bone-inducing protein
, prepro bone inducing protein
, growth/differentiation factor 10