anti-Gremlin 2 (GREM2) Antikörper

GREM2 encodes a member of the BMP (bone morphogenic protein) antagonist family. Zusätzlich bieten wir Ihnen Gremlin 2 Kits (12) und Gremlin 2 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GREM2 289264  
GREM2 23893 O88273
GREM2 64388 Q9H772
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Top anti-Gremlin 2 Antikörper auf antikoerper-online.de

Showing 10 out of 51 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert WB WB Suggested Anti-GREM2 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:312500 Positive Control: 721_B cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of Gremlin 2 expression in HEK293T (A), Raw264.7 (B), H9C2 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p) Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details
Huhn Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$245.00
Details
Human Kaninchen Unkonjugiert IP Immunoprecipitation of GREM2 transfected lysate using anti-GREM2 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with GREM2 purified MaxPab mouse polyclonal antibody (B01P) . 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$425.71
Details
Human Maus Unkonjugiert ELISA Detection limit for recombinant GST tagged GREM2 is 3 ng/ml as a capture antibody. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Maus Unkonjugiert WB Western Blot analysis of GREM2 expression in transfected 293T cell line by GREM2 MaxPab polyclonal antibody.<br><br>Lane 1: GREM2 transfected lysate(18.48 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μg Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert WB GREM2 antibody used at 1 ug/ml to detect target protein. 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
$473.93
Details
Human Kaninchen Unkonjugiert WB   100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$375.83
Details

GREM2 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Weitere Antikörper gegen Gremlin 2 Interaktionspartner

Zebrafish Gremlin 2 (GREM2) Interaktionspartner

  1. Through regulation of bone morphogenetic protein signaling, GREM2 is required for cardiac laterality and atrial differentiation during embryonic development.

  2. Gremlin 2 regulates distinct roles of BMP and Endothelin 1 (zeige EDN1 Antikörper) signaling in dorsoventral patterning of the facial skeleton.

  3. Prdc is expressed in the developing eyes and the first two pharyngeal arches, in the outer layers of the optic cup, in the arch mesenchyme expands stepwise to the remaining posterior arches, and in the somites and the the swim bladder.

Mouse (Murine) Gremlin 2 (GREM2) Interaktionspartner

  1. Grem2 knockdown inhibited cardiomyocyte differentiation, and this effect was similar to that of Notch1 (zeige NOTCH1 Antikörper) pathway inhibition in vitro. Grem2 enhances the protective effect of cardiac progenitor cells on heart function in a mouse model of myocardial infarction.

  2. Grem2 provides a molecular barrier that controls the extent of inflammatory cell infiltration by suppressing BMP2 (zeige BMP2 Antikörper) after myocardial infarction.

  3. Grem2 expression is regulated during development and embryonic stem cell differentiation.

  4. PRDC binds heparin with high affinity and that heparin binding to PRDC interferes with BMP antagonism.

  5. We show that Tbx2 directly represses Grem1 in distal regions of the posterior limb mesenchyme allowing Bone morphogenetic protein (Bmp) signaling to abrogate Fgf4/9/17 expression in the overlying epithelium.

  6. Through a combination of biophysical and biochemical studies, the authors determined that PRDC forms biologically active dimers that potently inhibit BMP ligands.

  7. The differential regulation of Gremlin2 gene expressions by BMP2 (zeige BMP2 Antikörper) may explain the critical function of these genes during osteoblast differentiation.

  8. ovarian PRDC expressed in granulosa cells could be involved in follicular development by antagonizing the actions of theca cell-derived Bone morphogenetic proteins

  9. We propose that PRDC might serve as a mediator to antagonize BMP-4 (zeige BMP4 Antikörper) signaling by Wnt (zeige WNT2 Antikörper).

  10. PRDC expression in osteoblasts suppresses differentiation and that reduction of PRDC expression promotes osteogenesis in vitro. PRDC is accordingly identified as a potential novel therapeutic target for the regulation of bone formation.

Human Gremlin 2 (GREM2) Interaktionspartner

  1. Data show that the GREMLIN 2 (GREM2) expression during Induced Pluripotent Stem Cell (hiPS) cell cardiac differentiation follows the expression pattern of cardiac-specific genes.

  2. The structure of Grem2-GDF5 (zeige GDF5 Antikörper) complex has revealed a number of key findings for DAN-family mediated BMP2 (zeige BMP2 Antikörper) inhibition.

  3. This study showed that si-Grem2 increased the BMP-2 (zeige BMP2 Antikörper)-induced osteogenic differentiation of hBMSCs via the BMP-2 (zeige BMP2 Antikörper)/Smad (zeige SMAD1 Antikörper)/Runx2 (zeige RUNX2 Antikörper) pathway.

  4. The present study shows that the Grem2 heparin/HS and BMP2 (zeige BMP2 Antikörper)-binding epitopes are unique and independent, where the Grem2-BMP2 (zeige BMP2 Antikörper) complex exhibits a significant increase in binding affinity toward heparin moieties that appear to be partially independent of the Grem2 heparin/HS-binding epitope.

  5. Gremlin 2 inhibits adipocyte differentiation through activation of Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling

  6. GREM2 variants have been identified in atrial fibrillation cohort studies, demonstrating abnormalities in cardiac excitation - supra ventricular tachycardia and atrial fibrillation.

  7. The minor allele of rs4454537 is significantly associated with low bone density at the total hip of southern Chinese people. Our study further suggests GREM2 as a novel susceptibility gene for osteoporosis.

  8. Through regulation of bone morphogenetic protein signaling, GREM2 is required for cardiac laterality and atrial differentiation during embryonic development.

  9. and that a genetic variant in the FMN2 (zeige FMN2 Antikörper)/GREM2 locus influences GREM2 expression in osteoblasts and thereby trabecular number and thickness as well as fracture risk.

Gremlin 2 (GREM2) Antigen-Profil

Protein Überblick

This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.

Genbezeichner und Symbole assoziert mit anti-Gremlin 2 (GREM2) Antikörper

  • gremlin 2, DAN family BMP antagonist (GREM2) Antikörper
  • gremlin 2, DAN family BMP antagonist b (grem2b) Antikörper
  • gremlin 2, cysteine knot superfamily (grem2) Antikörper
  • gremlin 2, DAN family BMP antagonist (grem2) Antikörper
  • gremlin 2, DAN family BMP antagonist (Grem2) Antikörper
  • CKTSF1B2 Antikörper
  • DAND3 Antikörper
  • Gremlin2 Antikörper
  • PRDC Antikörper
  • RGD1560008 Antikörper
  • zgc:112207 Antikörper

Bezeichner auf Proteinebene für anti-Gremlin 2 (GREM2) Antikörper

gremlin 2, cysteine knot superfamily, homolog (Xenopus laevis) , gremlin 2, cysteine knot superfamily, homolog , gremlin-2 , protein related to DAN and cerberus homolog , gremlin 2, cysteine knot superfamily , gremlin 2 homolog, cysteine knot superfamily , Gremlin1 , cysteine knot superfamily 1, BMP antagonist 2 , protein related to DAN and cerberus , DAN domain family member 3

GENE ID SPEZIES
421507 Gallus gallus
469727 Pan troglodytes
490367 Canis lupus familiaris
550399 Danio rerio
100194915 Salmo salar
100528649 Ictalurus punctatus
289264 Rattus norvegicus
23893 Mus musculus
64388 Homo sapiens
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