Granulin (GRN) ELISA Kits

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. Zusätzlich bieten wir Ihnen Granulin Antikörper (160) und Granulin Proteine (43) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
GRN 2896 P28799
GRN 29143 P23785
GRN 14824  
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Top Granulin ELISA Kits auf antikoerper-online.de

Showing 10 out of 122 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 1.95 pg/mL 7.8-500 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$910.56
Details
Maus 10pg/mL 0.78-50 ng/mL Mouse Progranulin PicoKine ELISA Kit standard curve 96 Tests Anmelden zum Anzeigen 4 bis 6 Tage
$369.00
Details
Ratte 0.065 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$640.00
Details
Meerschweinchen 1.0 pg/mL 50-1000 pg/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Kaninchen 1.0 pg/mL 50-1000 pg/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Huhn 1.875 ng/mL 3.125-200 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Schwein 0.938 ng/mL 1.563-100 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
$715.00
Details
Hund 1.0 pg/mL 50-1000 pg/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Affe 1.0 pg/mL 50-1000 pg/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details
Schaf
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
$707.14
Details

Am meisten referenzierte Granulin ELISA Kits

  1. Human Granulin ELISA Kit für Sandwich ELISA - ABIN578626 : Qu, Deng, Hu: Plasma progranulin concentrations are increased in patients with type 2 diabetes and obesity and correlated with insulin resistance. in Mediators of inflammation 2013 (PubMed)
    Show all 2 Pubmed References

  2. Rat (Rattus) Granulin ELISA Kit für Sandwich ELISA - ABIN4881274 : Zhou, Xie, Wang, Zhang, Chen, Zhang, Wu, Wei, Ding, Hang, Zhou, Shi: Decreased progranulin levels in patients and rats with subarachnoid hemorrhage: a potential role in inhibiting inflammation by suppressing neutrophil recruitment. in Journal of neuroinflammation 2015 (PubMed)

Weitere ELISA Kits für Granulin Interaktionspartner

Zebrafish Granulin (GRN) Interaktionspartner

  1. Findings show that miR (zeige MYLIP ELISA Kits)-145 and GrnA expression patterns are inversely correlated during liver development and provide evidence that GrnA-dependent hepatic outgrowth is regulated by miR (zeige MYLIP ELISA Kits)-145 in zebrafish embryonic development.

  2. the Grna and Grnb single and double knock out zebrafish lack any obvious morphological, pathological and biochemical phenotypes

  3. GrnA positively modulates hepatic MET expression both in vivo and in vitro.

Human Granulin (GRN) Interaktionspartner

  1. HSPA5 (GRP78 (zeige HSPA5 ELISA Kits)) and GEP were identified to interact. Clinical analysis showed that expression of GRP78 (zeige HSPA5 ELISA Kits) was up-regulated in hepatocellular carcinoma tumor and correlated with GEP expression.

  2. the expression of PGRN was significantly upregulated in Osteonecrosis of the Femoral Head patients' articular cartilage, and recombinant PGRN could promote expression of aggrecan (zeige ACAN ELISA Kits) and collagen II and the activation of ERK1/2 (zeige MAPK1/3 ELISA Kits).

  3. White matter hyperintensities are seen only in GRN mutation carriers in fronto-temporal dementia.

  4. The study provides solid evidence that there is the interaction between GRN A and ENO1 (zeige ENO1 ELISA Kits) and the interaction is responsible for the effects of GRN A on glucose uptake as well as cancer cell migration and invasion.

  5. This study ascertained that PGRN expression in airway epithelial cells inhibits CS-induced apoptosis, presumably through regulation of the ER stress response and MAPK (zeige MAPK1 ELISA Kits) activation.

  6. mTOR (zeige FRAP1 ELISA Kits) signaling contributes to PGRN-stimulated carcinogenesis of cervical cancer

  7. This study describe a novel GRN, p.(Tyr229*) mutation, resulting in haploinsufficiency of GRN and a severe neuropathologic FTLD phenotype.

  8. This meta-analysis supported the T allele of rs5848 within progranulin, as a risk factor for Alzheimer's Disease.

  9. Our case report further corroborates the notion that, in addition to FTD (zeige FTL ELISA Kits), progranulin may be involved in the neurobiology of bipolar disorder type 1, and suggests to screen patients with late-onset bipolar disorder for GRN mutations.

  10. GRN SNPs likely influence disease course and relapse recovery in multiple sclerosis.

Mouse (Murine) Granulin (GRN) Interaktionspartner

  1. PGRN plays a protecting role in hippocampal neurogenesis.

  2. This study ascertained that PGRN expression in airway epithelial cells inhibits CS-induced apoptosis, presumably through regulation of the ER stress response and MAPK (zeige MAPK1 ELISA Kits) activation.

  3. This study demonstrated that Progranulin overexpression in sensory neurons attenuates neuropathic pain in mice.

  4. The results of this study show that endogenous and recombinant PGRN limit axonal injury and astrogliosis and suggest therapeutic potential of PGRN in traumatic brain injury.

  5. progranulin expression is critical for tumor growth in vivo, in both xenograft and orthotopic tumor models

  6. Study demonstrate that PGRN interacts with the lysosomal protease CTSD (zeige CTSD ELISA Kits) and maintains its proper activity in vivo. Therefore, by regulating CTSD (zeige CTSD ELISA Kits) activity, PGRN may modulate protein homeostasis. This could potentially explain the TDP-43 (zeige TARDBP ELISA Kits) aggregation observed in frontotemporal lobar degeneration with GRN mutations.

  7. Findings suggest that elevated PGRN is linked to cognitive deficits of fragile X (zeige FMR1 ELISA Kits) syndrome.

  8. highlight an important role for neuron-derived progranulin in maintaining normal social function.

  9. overexpression of PGRN was also found to increase activity of neprilysin (zeige MME ELISA Kits), a key amyloid beta degrading enzyme. PGRN regulation of neprilysin (zeige MME ELISA Kits) activity could play a major role in the observed alterations in plaque burden

  10. PGRN decrease, resulting from pathogenic mutations, might compromise the trophism of cortical neurons by affecting GluN2B (zeige GRIN2B ELISA Kits)-contaning NMDA receptors

Guinea Pig Granulin (GRN) Interaktionspartner

  1. ADAM15 (zeige ADAM15 ELISA Kits) and acrogranin are present on and associated with the surface of guinea pig spermatozoa; besides both proteins may play a role during sperm-egg binding.

Granulin (GRN) Antigen-Profil

Beschreibung des Gens

Granulins are a family of secreted, glycosylated peptides that are cleaved from a single precursor protein with 7.5 repeats of a highly conserved 12-cysteine granulin/epithelin motif. The 88 kDa precursor protein, progranulin, is also called proepithelin and PC cell-derived growth factor. Cleavage of the signal peptide produces mature granulin which can be further cleaved into a variety of active, 6 kDa peptides. These smaller cleavage products are named granulin A, granulin B, granulin C, etc. Epithelins 1 and 2 are synonymous with granulins A and B, respectively. Both the peptides and intact granulin protein regulate cell growth. However, different members of the granulin protein family may act as inhibitors, stimulators, or have dual actions on cell growth. Granulin family members are important in normal development, wound healing, and tumorigenesis.

Genbezeichner und Symbole assoziert mit Granulin (GRN) ELISA Kits

  • granulin precursor (GRN) Antikörper
  • granulin a (grna) Antikörper
  • Granulins (grn) Antikörper
  • granulin L homeolog (grn.L) Antikörper
  • granulin (granulin) Antikörper
  • granulin (ORF1 granulin) Antikörper
  • granulin precursor (Grn) Antikörper
  • granulin (Grn) Antikörper
  • acrogranin Antikörper
  • CLN11 Antikörper
  • DKFZp459H066 Antikörper
  • epithelin Antikörper
  • GEP Antikörper
  • GP88 Antikörper
  • grn Antikörper
  • MGC53354 Antikörper
  • PCDGF Antikörper
  • PEPI Antikörper
  • PGRN Antikörper
  • wu:fb11g12 Antikörper
  • wu:fj18f05 Antikörper

Bezeichner auf Proteinebene für Granulin (GRN) ELISA Kits

granulin , granulin-a , zfPGRN-A , Granulins , PC cell-derived growth factor , acrogranin , granulin-epithelin , granulins , proepithelin , progranulin , PCDGF , PEPI , acrogranulin

GENE ID SPEZIES
454728 Pan troglodytes
100051035 Equus caballus
791524 Danio rerio
100195018 Salmo salar
380370 Xenopus laevis
1463344 Adoxophyes orana granulovirus
2776804 Agrotis segetum granulovirus
100173689 Pongo abelii
2896 Homo sapiens
29143 Rattus norvegicus
14824 Mus musculus
480501 Canis lupus familiaris
733645 Sus scrofa
767942 Bos taurus
100135533 Cavia porcellus
100349528 Oryctolagus cuniculus
101115470 Ovis aries
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