anti-Gonadotropin-Releasing Hormone Receptor (GNRHR) Antikörper

Human Gonadotropin-Releasing Hormone Receptor (GNRHR) Interaktionspartner

1. GNRHR (and GNRH) are expressed in trophoblast cell populations and fallopian tube epithelium at tubal ectopic pregnancy sites.

2. first description of a GNRHR gene mutation in three patients diagnosed with polycystic ovary syndrome.

3. We showed that GNRHR and LHCGR were highly expressed in some wildtype aldosterone-producing adenoma samples, and that they positively correlated with GnRH-stimulated aldosterone production.

4. Results show that biallelic gonadotropin releasing hormone receptor (GNRHR) mutations are not a frequent cause of age-related androgen decline in men.

5. GnRH receptors on triple negative breast cancer cells can be used for targeted therapy of these cancers with GnRH agonist triptorelin

6. study found a novel mutation in PROK2 (zeige PROK2 Antikörper) in two male siblings presenting normosmic congenital hypogonadotropic hypogonadism, in whom a mutation in the GNRHR gene had been previously described, suggesting the possibility of a digenic inheritance

7. Data suggest differences in regulation of expression of PEDF (zeige SERPINF1 Antikörper) (up-regulation) vs. VEGF (zeige VEGFA Antikörper) (down-regulation) in granulosa cells explain reduced risk of ovarian hyperstimulation syndrome due to ovulation induction using GnRH (zeige GNRH1 Antikörper)/GNRHR agonists rather than hCG (zeige CGA Antikörper).

8. A high prevalence of endometriosis, polymorphism in the LHCGR and GnRH1 and progonadoliberin-2 antibodies in serum was found among the patients with severe dysmotility after treatment with GnRH analogs.

9. No abnormalities were found in the patient group for the PROKR2 (zeige PROKR2 Antikörper) and GNRH1genes. In addition, no genomic rearrangements were identified in the healthy control individuals for the described genes

10. Mutations were found in the following genes in one or more patients with congenital hypogonadotropic hypogonadism: KAL1 (zeige KAL1 Antikörper), FGFR1 (zeige FGFR1 Antikörper), GNRHR, and CHD7 (zeige CHD7 Antikörper)

Rabbit Gonadotropin-Releasing Hormone Receptor (GNRHR) Interaktionspartner

1. These results suggest that GNRHR-I is constitutively expressed in rabbit corpora lutea independently of luteal stage of pseudopregnant rabbits.

Mouse (Murine) Gonadotropin-Releasing Hormone Receptor (GNRHR) Interaktionspartner

1. leptin's direct stimulatory actions on gonadotrope GnRHR correlate with a direct inhibition of expression of the posttranscriptional regulator MSI1 (zeige MSI1 Antikörper). There also is a direct MSI1 (zeige MSI1 Antikörper) interaction with 3'-UTR (zeige UTS2R Antikörper) of Gnrhr mRNA.

2. the age-dependent basal and regulated Gnrhr transcription could account for the initial blockade and subsequent activation of the reproductive system during development.

3. GnRH (zeige GNRH1 Antikörper)-GnRHR system is not essential for growth or motor/sensory/orientation behavior during the first month of life prior to puberty onset. The lack of the GnRH (zeige GNRH1 Antikörper)-GnRHR axis, however, did affect females resulting in reduced subcutaneous inguinal fat pad (zeige DHX40 Antikörper) weight and increased glucose with possible insulin (zeige INS Antikörper) resistance.

4. His305 of the GnRH receptor forms two distinct interactions that determine binding to GnRH and couple agonist binding to the conserved transmembrane domain network that activates GPCRs.

5. The aims of this study were to explore whether mRNA-levels of gonadotropin-releasing hormone (Gnrh (zeige GNRH1 Antikörper)) and its receptor (Gnrhr) were changed in plaque-bearing Alzheimer's disease transgenic mice.

6. Data confirm that Gnrhr mRNA and protein are expressed in ovaries, granulosa cells, cumulus cells, and oocytes.

7. Msx1 (zeige MSX1 Antikörper) functions as a negative regulator early in pituitary development by repressing the gonadotrope-specific alphaGSU (zeige CGA Antikörper) and GnRHR genes.

8. These results suggest decreased GnRH receptor signaling in the mutant animal, compared with wild type.

9. Report down-regulation of ErbB4 (zeige ERBB4 Antikörper) expression in hypothalamic neurons induced by G-protein-coupled gonadotropin releasing hormone receptor stimulation.

10. GnRHR neurons were found in different brain areas. Many GnRHR neurons were identified in areas influencing sexual behaviors

Cow (Bovine) Gonadotropin-Releasing Hormone Receptor (GNRHR) Interaktionspartner

1. The GRIA1 (zeige GRIA1 Antikörper) polymorphism exists in beef cows but it does not influence antral follicle numbers. The association between GnRHR genotype and age at first calving is likely not causal as this polymorphism is not functional.

2. There was a significant correlation between frequency profile and timing of puberty among the studied breeds, which seems to suggest that genetic variation within bovine GNRHR gene could explain at least part of the reported variability.

3. These results indicate that GnRHR gene can be a potential marker for improving sperm quality traits, and imply that bulls with GA or CT genotype should be selected in breeding program.

4. Seven sequence variants (SVs) have been identified in exon 1 and in the promoter region upstream of the bovine gonadotrophin releasing hormone (GnRH) receptor; g.-108T>C alteration was associated with beneficial effects on fertility

Rainbow Trout (Oncorhynchus mykiss) Gonadotropin-Releasing Hormone Receptor (GNRHR) Interaktionspartner

1. Data show that GnRH (zeige GNRH1 Antikörper) stimulates phagocytosis in fish leucocytes through a GnRH-receptor-dependent pathway.