Glucosidase beta 2 (GBA2) ELISA Kits

Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide. Zusätzlich bieten wir Ihnen GBA2 Antikörper (3) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
Anti-Maus GBA2 GBA2 230101 Q69ZF3
GBA2 298399  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Ratte 1.875 ng/mL 3.125 ng/mL - 200 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 16 Tage
  96 Tests Anmelden zum Anzeigen 16 bis 21 Tage

Weitere ELISA Kits für GBA2 Interaktionspartner

Mouse (Murine) Glucosidase beta 2 (GBA2) Interaktionspartner

  1. sphingosine, the cytotoxic metabolite accumulating in Gaucher cells through the action of GBA2, directly binds to GBA2 and inhibits its activity.

  2. GBA2 is particularly abundant in Purkinje cells (PCs), one of the most affected neuronal populations in NPC (zeige NPC1 ELISA Kits) disease.

  3. glucosylceramide accumulation in GBA2 knockout-mice alters cytoskeletal dynamics due to a more ordered lipid organization in the plasma membrane. Similar cytoskeletal defects were observed in male germ and Sertoli cells from GBA2 knockout-mice.

  4. the deletion of Gba2 significantly rescues the type 1 Gaucher disease clinical phenotype.

  5. redefine GBA2 activity as the beta-glucosidase that is sensitive to inhibition by N-butyldeoxygalactonojirimycin.

  6. GBA2 is localized at the ER and Golgi, which puts GBA2 in a key position for a lysosome-independent route of glucosylceramide-dependent signaling.

  7. The repression of IL-6/STAT3 signalling pathway seems to be one of the mechanisms for the delay of liver regeneration in GBA2-deficient mice.

  8. GBA1 and GBA2 activities had characteristic differences between the studied fibroblast, liver and brain samples.

  9. The coiled-coil structure of LIMP-2 (zeige SCARB2 ELISA Kits) is required for its interaction with beta-glucocerebrosidase (zeige GBA ELISA Kits).

  10. L-type calcium channel blockers have the ex vivo effects of increasing GCase (zeige GBA ELISA Kits) activity and protein in mouse fibroblasts

GBA2 Antigen-Profil

Beschreibung des Gens

Non-lysosomal glucosylceramidase that catalyzes the conversion of glucosylceramide to free glucose and ceramide. Involved in sphingomyelin generation and prevention of glycolipid accumulation. May also catalyze the hydrolysis of bile acid 3-O- glucosides, however, the relevance of such activity is unclear in vivo.

Genbezeichner und Symbole assoziert mit Glucosidase beta 2 (GBA2) ELISA Kits

  • glucosidase beta 2 (Gba2) Antikörper
  • glucosylceramidase beta 2 (Gba2) Antikörper
  • F630034E04 Antikörper

Bezeichner auf Proteinebene für Glucosidase beta 2 (GBA2) ELISA Kits

NLGase , beta-glucocerebrosidase 2 , beta-glucosidase 2 , bile acid , glucosidase, beta (bile acid) 2 , glucosylceramidase 2 , non-lysosomal glucosylceramidase , bile acid beta-glucosidase

230101 Mus musculus
298399 Rattus norvegicus
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