anti-General Transcription Factor III (GTF2I) Antikörper

GTF2I encodes a multifunctional phosphoprotein with roles in transcription and signal transduction. Zusätzlich bieten wir Ihnen GTF2I Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GTF2I 2969 P78347
GTF2I 353256 Q5U2Y1
GTF2I 14886 Q9ESZ8
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Top anti-GTF2I Antikörper auf antikoerper-online.de

Showing 10 out of 125 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-GTF2I Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-GTF2I Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>293T cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Hund Maus Unkonjugiert IF, WB Western blot analysis of TFII-I on HeLa cell lysate. Lane 1: 1:1000, lane 2: 1:2000, lane 3: 1:4000 dilution of anti-TFII-I. Immunofluorescent staining of FHS cells. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$168.74
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of extracts from LOVO cells, using TFII-I (Phospho-Tyr248) Antibody. The lane on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert EIA, WB   0.4 mL Anmelden zum Anzeigen 12 bis 15 Tage
$518.65
Details
Human Kaninchen Unkonjugiert FACS, IF, IHC (p), WB Western blot analysis of GTF2I Antibody (C-term) (ABIN390868) in Y79 cell line lysates (35 µg/lane). GTF2I (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with GTF2I Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of GTF2I staining in rat brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the ant Western blot analysis of GTF2I expression in MCF7 (A), BT474 (B), Hela (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Fledermaus Kaninchen Unkonjugiert IHC (p), WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert IHC (p), ELISA Human Prostate (formalin-fixed, paraffin-embedded) stained with GTF2I antibody ABIN364488 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Small Intestine (formalin-fixed, paraffin-embedded) stained with GTF2I antibody ABIN364488 at 10 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$639.83
Details

GTF2I Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-GTF2I Antikörper

  1. Dog (Canine) Monoclonal GTF2I Primary Antibody für IF, WB - ABIN968264 : Yang, Desiderio: BAP-135, a target for Bruton's tyrosine kinase in response to B cell receptor engagement. in Proceedings of the National Academy of Sciences of the United States of America 1997 (PubMed)

  2. Human Polyclonal GTF2I Primary Antibody für ICC, IF - ABIN4358737 : Lopez-Contreras, Ruppen, Nieto-Soler, Murga, Rodriguez-Acebes, Remeseiro, Rodrigo-Perez, Rojas, Mendez, Muñoz, Fernandez-Capetillo: A proteomic characterization of factors enriched at nascent DNA molecules. in Cell reports 2013 (PubMed)

  3. Cow (Bovine) Polyclonal GTF2I Primary Antibody für IHC, WB - ABIN2787508 : Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: Large-scale mapping of human protein-protein interactions by mass spectrometry. ... in Molecular systems biology 2007 (PubMed)

  4. Human Monoclonal GTF2I Primary Antibody für IF, IHC (p) - ABIN561180 : Poitras, Yu, Lesage-Pelletier, Macdonald, Gagné, Hatch, Kelly, Hamilton, Rubenstein, Poirier, Ekker: An SNP in an ultraconserved regulatory element affects Dlx5/Dlx6 regulation in the forebrain. in Development (Cambridge, England) 2010 (PubMed)

Weitere Antikörper gegen GTF2I Interaktionspartner

Human General Transcription Factor III (GTF2I) Interaktionspartner

  1. GTF2I/Gtf2i, its physiologic role in human disorders was relatively unknown until recently. Novel studies show that it is involved in an array of human diseases including neurocognitive disorders, systemic lupus erythematosus (SLE), and cancer.

  2. the results reported here support a model whereby common genetic variation in GTF2I mediates human sociality and anxiety via effects on oxytocin reactivity.

  3. GTF2I mutations common in thymic epithelial tumors are not present/uncommon in hematological malignancies.

  4. The mis-regulation of genes downstream of GTF2IRD1, including TbetaR2 and BMPR1b, also individually promoted mammary cancer development, and silencing of TbetaR2 suppressed GTF2IRD1-driven tumor promotion.

  5. a new BRAF (zeige BRAF Antikörper) fusion in pilocytic astrocytoma

  6. A common polymorphism in the Williams syndrome gene GTF2I associated with reduced social anxiety predicts decreased threat-related amygdala reactivity, which mediates an association between genotype and increased warmth in women.

  7. We identified rs117026326 on GTF2I with GWAS significance (P = 1.10 x 10(-15)) and rs13079920 on RBMS3 (zeige RBMS3 Antikörper) with suggestive significance (P = 2.90 x 10(-5)) associating with Primary Sjogren's syndrome in women.

  8. The authors found that human adenovirus 5 infection or ectopic E4-ORF3 (zeige ASZ1 Antikörper) expression leads to SUMOylation of TFII-I that precedes a rapid decline in TFII-I protein levels.

  9. A novel interaction between TFII-I and Mdm2 (zeige MDM2 Antikörper) with a negative effect on TFII-I transcriptional activity has been documented.

  10. Copy-number variation in the general transcription factor gene, GTF2I is associated with gene-dose-dependent anxiety in mouse models and in both Williams syndrome and Dup7.

Mouse (Murine) General Transcription Factor III (GTF2I) Interaktionspartner

  1. The Cre-mediated deletion of exon 3 recapitulates a genetic null phenotype, indicating that the conditional Gtf2i line is a valuable tool for studying TFII-I function during embryonic development

  2. found a highly conserved DNA element, common to a set of genes regulated by TFII-I, and identified and validated novel in vivo neuronal targets of this protein affecting the PI3K and TGFbeta (zeige TGFB1 Antikörper) signaling pathways

  3. GTF2IRD2 (zeige GTF2IRD2 Antikörper) has evolved as a regulator of GTF2IRD1 and TFII-I; inhibiting their function by direct interaction and sequestration into inactive nuclear zones.

  4. data support the hypothesis that upregulation of TFII-I factors leads to activation of a specific group of developmental genes during mESC differentiation

  5. GTF2I duplication results in separation anxiety in mice and humans

  6. In order to clarify the involvement of GTF2I in neurocognitive function, especially social behavior, we have developed and characterized Gtf2i-deficient mice.

  7. Results suggest that DJ-1 (zeige PARK7 Antikörper) together with TFII-I operate in concert to cope with various insults and to sustain pancreatic beta-cell function.

  8. behavioral characterization of heterozygous mice with a deletion of the first 140 amino-acids of TFII-I.

  9. data demonstrate that TFII-I, through a Src (zeige SRC Antikörper)-dependent mechanism, reversibly translocates from the cytoplasm to the nucleus, leading to the transcriptional activation of growth-regulated genes

  10. acts as a transcriptional cofactor for the SUMO ubiquitin-protein isopeptide ligase family member Miz1/PIASxbeta /Siz2 (zeige PIAS2 Antikörper)

GTF2I Antigen-Profil

Protein Überblick

The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit GTF2I

  • general transcription factor IIi (GTF2I) Antikörper
  • GTF2I repeat domain containing 1 (GTF2IRD1) Antikörper
  • general transcription factor II I (Gtf2i) Antikörper
  • general transcription factor IIi (gtf2i) Antikörper
  • general transcription factor IIi (Gtf2i) Antikörper
  • general transcription factor IIi S homeolog (gtf2i.S) Antikörper
  • 6030441I21Rik Antikörper
  • bap-135 Antikörper
  • bap135 Antikörper
  • BEN Antikörper
  • btkap1 Antikörper
  • CREAM1 Antikörper
  • diws Antikörper
  • gtf2i Antikörper
  • gtf2i.L Antikörper
  • Gtf2ird1 Antikörper
  • GTF3 Antikörper
  • gtfii-i Antikörper
  • hMusTRD1alpha1 Antikörper
  • ib291 Antikörper
  • MUSTRD1 Antikörper
  • RBAP2 Antikörper
  • spin Antikörper
  • tfii-i Antikörper
  • wbs Antikörper
  • wbscr6 Antikörper
  • WBSCR11 Antikörper
  • WBSCR12 Antikörper

Bezeichner auf Proteinebene für GTF2I

BTK-associated protein, 135kD , Bruton tyrosine kinase-associated protein 135 , SRF-Phox1-interacting protein , Williams-Beuren syndrome chromosome region 6 , general transcription factor II-I , USE B1-binding protein , Williams-Beuren syndrome chromosome region 11 , binding factor for early enhancer , general transcription factor 3 , general transcription factor II-I repeat domain-containing protein 1 , general transcription factor III , muscle TFII-I repeat domain-containing protein 1 alpha 1 , slow-muscle-fiber enhancer-binding protein , williams-Beuren syndrome chromosomal region 12 protein , GTFII-I , TFII-I , BTK-associated protein 135 , general transcription factor II, i , general transcription factor IIi L homeolog , general transcription factor IIi S homeolog

GENE ID SPEZIES
2969 Homo sapiens
9569 Homo sapiens
353256 Rattus norvegicus
14886 Mus musculus
534669 Bos taurus
549986 Xenopus (Silurana) tropicalis
417486 Gallus gallus
479714 Canis lupus familiaris
100724513 Cavia porcellus
443780 Xenopus laevis
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