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GTF2IRD2 is unusual in that its coding sequence is mostly derived from Charlie8 repeat elements. Zusätzlich bieten wir Ihnen GTF2I Repeat Domain Containing 2 Proteine (3) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal GTF2IRD2 Primary Antibody für IF, WB - ABIN529591
Palmer, Taylor, Santucci, Widagdo, Chan, Yeo, Adams, Gunning, Hardeman: GTF2IRD2 from the Williams-Beuren critical region encodes a mobile-element-derived fusion protein that antagonizes the action of its related family members. in Journal of cell science 2013
Show all 2 Pubmed References
We provide the first evidence for a role for GTF2IRD2 in higher-level (executive functioning) abilities and highlight the importance of integrating detailed molecular characterisation of patients with comprehensive neuropsychological profiling
Williams-Beuren syndrome patients are hemizygous for the GTF2IRD2 gene.
GTF2IRD2 genes in mice and humans allows refinement of the centromeric breakpoint position of the primate-specific inversion within the Williams-Beuren syndrome critical region.
GTF2IRD2 has evolved as a regulator of GTF2IRD1 and TFII-I (zeige GTF2I Antikörper); inhibiting their function by direct interaction and sequestration into inactive nuclear zones.
expression of TFII-I (zeige GTF2I Antikörper) gene family were mapped in embryonic tooth germs; at bud stage, Gtf2ird1 & Gtf2ird2 were expressed in epithelial buds; at early bell stage, expression of Gtf2ird1 & Gtf2ird2 was observed in preameloblasts & preodontoblasts
This gene is unusual in that its coding sequence is mostly derived from Charlie8 repeat elements. However, there is mRNA and EST evidence to suggest that this gene is transcribed, and the encoded protein has a homolog in mouse, with which it shares 78% sequence identity. The exact function of this gene product is not known. It is inferred to be a transcription factor based on the presence of GTF2I-like repeats (containing helix-loop-helix motifs), also found in other proteins such as GTF2IRD1 and GTF2I. These three genes are clustered together on chr 7q11.23.
GTF2I repeat domain-containing protein 2, alpha
, GTF2I repeat domain-containing protein 2A
, general transcription factor II i repeat domain 2 alpha
, general transcription factor II-I repeat domain-containing protein 2A
, transcription factor GTF2IRD2-alpha
, GTF2I repeat domain-containing protein 2
, general transcription factor II-I repeat domain-containing protein 2
, transcription factor GTF2IRD2
, Transcription factor GTF2IRD2