anti-GDNF Family Receptor alpha 1 (GFRA1) Antikörper

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. Zusätzlich bieten wir Ihnen GDNF Family Receptor alpha 1 Kits (27) und GDNF Family Receptor alpha 1 Proteine (26) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GFRA1 2674 P56159
GFRA1 14585 P97785
GFRA1 25454 Q62997
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Top anti-GDNF Family Receptor alpha 1 Antikörper auf antikoerper-online.de

Showing 10 out of 96 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- GFRA1 antibody, IHC(P) IHC(P): Human Lung Cancer Tissue Anti- GFRA1 antibody, Western blotting All lanes: Anti GFRA1  at 0.5ug/ml WB: Recombinant Human GFRA1 Protein 0.5ng Predicted bind size: 39KD Observed bind size: 39KD 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
€247.79
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Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB Western Blot: GFR alpha-1/GDNF R alpha-1 Antibody [NBP1-77043] - Analysis for GFRa-1 using NBP1-77043 at 2 ug/ml dilution against 20 ug/lane of lysates of crude membrane fractions of human brain (lane 1), liver (lane 2), kidney (lane 3), and spleen (lane 4), respectively. Immunohistochemistry: GFR alpha-1/GDNF R alpha-1 Antibody [NBP1-77043] - Analysis of GFR alpha 1 in human brain tissue with GFR alpha 1 antibody at 2.5 ug/ml. 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
€432.50
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Human Maus Unkonjugiert WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
€355.31
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Human Maus Unkonjugiert FACS, IP 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
€355.31
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Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using GFR alpha-1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
€267.70
Details
Human Kaninchen Unkonjugiert ELISA, IHC, WB Western blot analysis of Mouse kidney lysate, using GFRA1 Antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6277552 at 1/100 staining Human liver cancer tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22¡ãC. An HRP conjugated goat anti-rabbit antibody was used as the secondary 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
€345.81
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Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p) 100 μL Anmelden zum Anzeigen 11 bis 14 Tage
€436.43
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Maus Kaninchen Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
€193.72
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Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 15 bis 19 Tage
€466.40
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-GDNFRA Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded human colon carcinoma labeled with Anti-GDNFRA Polyclonal Antibody, Unconjugated  at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
€291.55
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Am meisten referenzierte anti-GDNF Family Receptor alpha 1 Antikörper

  1. Human Polyclonal GFRA1 Primary Antibody für IHC (p), WB - ABIN2473776 : Treanor, Goodman, de Sauvage, Stone, Poulsen, Beck, Gray, Armanini, Pollock, Hefti, Phillips, Goddard, Moore, Buj-Bello, Davies, Asai, Takahashi, Vandlen, Henderson, Rosenthal: Characterization of a multicomponent receptor for GDNF. in Nature 1996 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal GFRA1 Primary Antibody für ELISA, IHC - ABIN4314060 : Lozada, Karlstedt, Panula, Aarnisalo: Unilateral labyrinthectomy induced changes on GDNF receptor complex proteins in the rat medial vestibular nuclei. in Journal of vestibular research : equilibrium & orientation 2007 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal GFRA1 Primary Antibody für IF (p) - ABIN726234 : Li, Bhave, Chow, Riera, Schlee, Rauch, Atanasova, Cate, Whitty: Quantitative analysis of receptor tyrosine kinase-effector coupling at functionally relevant stimulus levels. in The Journal of biological chemistry 2015 (PubMed)

  4. Human Polyclonal GFRA1 Primary Antibody für IHC, ELISA - ABIN1002344 : Sanicola, Hession, Worley, Carmillo, Ehrenfels, Walus, Robinson, Jaworski, Wei, Tizard, Whitty, Pepinsky, Cate: Glial cell line-derived neurotrophic factor-dependent RET activation can be mediated by two different cell-surface accessory proteins. in Proceedings of the National Academy of Sciences of the United States of America 1997 (PubMed)
    Show all 4 Pubmed References

  5. Human Polyclonal GFRA1 Primary Antibody für IF (p), IHC (p) - ABIN726230 : Ma, Zhou, Li, Zheng, Wu, Niu, Tang, He, Li, Hua: Lin28a promotes self-renewal and proliferation of dairy goat spermatogonial stem cells (SSCs) through regulation of mTOR and PI3K/AKT. in Scientific reports 2016 (PubMed)

Weitere Antikörper gegen GDNF Family Receptor alpha 1 Interaktionspartner

Human GDNF Family Receptor alpha 1 (GFRA1) Interaktionspartner

  1. circGFRA1 may function as a competing endogenous RNA (ceRNA) to regulate GFRA1 expression through sponging miR-34a to exert regulatory functions in TNBC.

  2. the methylation status of CpG sites in GFRA1 and GSTM2 may have a role and could be used as potential biomarkers for the screening of rectal cancer

  3. GFRA1 regulates AMPK-dependent autophagy by promoting SRC phosphorylation independent of proto-oncogene RET kinase

  4. that the consequences of this is that GFRalpha-1-mediated signalling is altered during the ageing process

  5. RET c.1296A may be a common susceptibility allele for nephron underdosing-related diseases. The 5'-UTR and intronic variants near exon 5 of GFRA1 are not associated with nephron endowment.

  6. Hox proteins coordinate motor neuron differentiation and connectivity programs through Ret/Gfra genes.

  7. This study demonstrate, using a knock-in mouse model in which GFRalpha1 is no longer located in lipid rafts, that the developmental functions of GDNF in the periphery require the translocation of the GDNF receptor complex into lipid rafts.

  8. Methylation changes of GFRA1, SRF, and ZNF382 may be a potential biomarker set for prediction of gastric carcinoma metastasis.

  9. GFRalpha1 levels in neurons from autopsied AD brains are significantly decreased.

  10. In the cochlea, GFRalpha-1 was identified mainly in the cell bodies of the spiral neurons. In the organ of Corti, GFRalpha-1 was demonstrated in the Deiters' cells, Hensen cells, inner pillar cells, and weakly in inner hair cells but not in the outer hair cells.

  11. These findings collectively demonstrate that GFRalpha1 released by nerves enhances perineural invasion through GDNF-RET signaling and that GFRalpha1 expression by cancer cells enhances but is not required for it.

  12. The study shows co-localization of RET with GFRA1 and GFRA2 in myenteric ganglia of the adult human colon.

  13. The expression of GFRalpha1 and/or GFRalpha3, especially when combined with ARTN expression, may be useful predictors of disease progression and outcome in specific subtypes of mammary carcinoma.

  14. Mutations in GFRA1 gene is associated with urinary tract malformations.

  15. Post-synaptic transgenic GFRalpha1 has profound effects on the development of dopamine neurons, resulting in a 40% increase in the adult number.

  16. This study found nominally-significant evidence for interactions between GFRA1, 2 and 3 associated with schizophrenia and clozapine response, consistent with the locations of these three genes within linkage regions for schizophrenia.

  17. Results identify persephin, a GDNF family member, as a novel ligand for GFRalpha1/RET receptor complex.

  18. MEN2 arises from activating missense mutations in RET, causing autodimerization under certain conditions. The position of missense mutations influences medullary thyroid carcinoma aggressiveness. Review.

  19. Here we report that human nigral dopaminergic neurons express GFRalpha1 and RET receptors at all ages. There was no reduction in the number of neurons expressing these receptors as a function of age.

  20. GFR-alpha1 mRNA transcripts were detected in oocytes and GCs from all samples from fetuses, girls and adult women.

Mouse (Murine) GDNF Family Receptor alpha 1 (GFRA1) Interaktionspartner

  1. these data provide support for a model of a stem cell pool in which the GFRa1+ and GFRa1- cells are closely related but show key cell-intrinsic differences and can interconvert between the two states based, in part, on access to niche factors.

  2. We further find that overexpression of NANOS2 results in the repression of GFRA1 and PLZF in gonocytes, leading to a delay in GST. On the other hand, loss of NANOS2 results in the up-regulation of GFRA1 and PLZF, indicating a precocious entry of GST.

  3. Western blot and immunofluorescence analyses showed two GIP-anchored proteins were clearly involved in the fertilisation process, namely growth arrest specific 1 (Gas1) and glial cell line-derived neurotrophic factor receptor alpha1 (Gfralpha1). This was demonstrated by evaluating oocyte fertilisability after treatment of oocytes with antibodies against the selected proteins, with their respective short interference RN...

  4. Compromised Survival of Cerebellar Molecular Layer Interneurons Lacking GDNF Receptors GFRalpha1 or RET Impairs Normal Cerebellar Motor Learning.

  5. GFRA1 regulates AMPK-dependent autophagy by promoting SRC phosphorylation independent of proto-oncogene RET kinase

  6. the neural cell adhesion molecule NCAM is co-expressed and directly interacts with GFRalpha1 in embryonic Purkinje cells.

  7. The GDNF-GFRalpha1 complex is essential for proper hippocampal circuit development.

  8. GDNF signals were able to induce the stratified aggregate formation of GFRalpha1-positive undifferentiated spermatogonia

  9. LncRNA033862 is an antisense transcript of the GDNF receptor alpha1 (Gfra1) that lacks protein coding potential and regulates Gfra1 expression levels by interacting with Gfra1 chromatin.

  10. These findings collectively demonstrate that GFRalpha1 released by nerves enhances perineural invasion through GDNF-RET signaling and that GFRalpha1 expression by cancer cells enhances but is not required for it.

  11. Gfra1 expression in the urinary tract strictly depends on cell-type and specific stage in kidney development.

  12. SorLA acts as sorting receptor for the GDNF/GFRalpha1 complex, directing it from the cell surface to endosomes.

  13. our data demonstrate that RET/GFRalpha signals are dispensable for thymic T cell development in vivo

  14. GFRalpha1 is critical for the development and function of the main olfactory system, contributing to the development and allocation of all major classes of neurons and glial cells.

  15. Donor-derived GFRalpha1-positive cells formed several aggregates of A(al(aligned)) /morula-like structures in a single spermatogenic cell patch before and on day 14 post-transplant, indicating involvement in the formation of a stable spermatogenic colony.

  16. GFRA1 expression is regulated by GDNF and in cultures of isolated seminiferous tubules, we found that GDNF expression and secretion by Sertoli cells is stage-dependent, being maximal in stages II-VI and decreasing thereafter.

  17. Histone methylation and acetylation regulate Pou5f1 and Gfra1 in male germ cell.

  18. Following ischemic injury, GFR alpha-1 is differentially up-regulated in GFR alpha-1 (+/+) and GFR alpha-1 (+/-) mice.

  19. GDNF/GFRalpha1 are involved in the survival and differentiation of double negative immature thymocytes.

  20. localization pattern of c-kit, Notch-1 and GFRalpha-1 in postnatal, immature and adult testes

GDNF Family Receptor alpha 1 (GFRA1) Antigen-Profil

Protein Überblick

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene.

Genbezeichner und Symbole assoziert mit GFRA1

  • GDNF family receptor alpha 1 (gfra1) Antikörper
  • GDNF family receptor alpha 1 (GFRA1) Antikörper
  • glial cell line derived neurotrophic factor family receptor alpha 1 (Gfra1) Antikörper
  • GDNF family receptor alpha 1 (Gfra1) Antikörper
  • gdnf family receptor alpha 1a (gfra1a) Antikörper
  • AU042498 Antikörper
  • GDNFR Antikörper
  • GDNFRA Antikörper
  • GDNFRALPHA Antikörper
  • GFR-ALPHA-1 Antikörper
  • GFRA1 Antikörper
  • gfralpha1a Antikörper
  • MGC122616 Antikörper
  • RET1L Antikörper
  • RETL1 Antikörper
  • TRNR1 Antikörper
  • zgc:110129 Antikörper

Bezeichner auf Proteinebene für GFRA1

GDNF family receptor alpha 1 , GDNF family receptor alpha-1 , GDNF receptor alpha-1 , GDNFR-alpha-1 , GPI-linked anchor protein , Glial cell line-derived neurotrophic factor receptor alpha , PI-linked cell-surface accessory protein , RET ligand 1 , TGF-beta related neurotrophic factor receptor 1 , TGF-beta-related neurotrophic factor receptor 1 , GDNF receptor alpha , GFR-alpha-1 , GDNF family receptor alpha-1-like , GDNFR-alpha , GFR alpha-1 , glial cell line derived neurotrophic factor family receptor alpha 1 , gdnf family receptor alpha 1a

GENE ID SPEZIES
100125202 Xenopus (Silurana) tropicalis
2674 Homo sapiens
395994 Gallus gallus
450756 Pan troglodytes
534801 Bos taurus
609114 Canis lupus familiaris
100338839 Oryctolagus cuniculus
100390427 Callithrix jacchus
100580436 Nomascus leucogenys
14585 Mus musculus
25454 Rattus norvegicus
79376 Danio rerio
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