anti-Formin Binding Protein 1-Like (FNBP1L) Antikörper

The protein encoded by FNBP1L binds to both CDC42 and N-WASP. Zusätzlich bieten wir Ihnen FNBP1L Kits (6) und FNBP1L Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Gen	GeneID	UniProt
FNBP1L	54874	Q5T0N5
FNBP1L	214459	Q8K012
FNBP1L	310839	Q2HWF0

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Top anti-FNBP1L Antikörper auf antikoerper-online.de

Showing 10 out of 64 products:

Katalog Nr.	Reaktivität	Wirt	Konjugat	Applikation	Menge	Anbieter	Lieferzeit	Preis	Details
ABIN952346	Human	Kaninchen	Unkonjugiert	EIA, WB	0.4 mL	Anmelden zum Anzeigen	6 bis 8 Tage	$484.00	Details
ABIN1538340	Human	Kaninchen	Unkonjugiert	WB	400 μL	Anmelden zum Anzeigen	10 bis 11 Tage	$385.00	Details
ABIN5555360	Human	Kaninchen	Unkonjugiert	EIA, IHC (p), WB	0.1 mg	Anmelden zum Anzeigen	4 bis 8 Tage	$474.10	Details
ABIN5555359	Human	Kaninchen	Unkonjugiert	EIA, IHC (p), WB	0.1 mg	Anmelden zum Anzeigen	4 bis 8 Tage	$474.10	Details
ABIN4312252	Human	Kaninchen	Unkonjugiert	ICC, IF, IHC, IHC (p)	0.1 mL	Anmelden zum Anzeigen	10 bis 13 Tage	$494.38	Details
ABIN461907	Human	Kaninchen	Unkonjugiert	ELISA, IHC, IHC (p), WB	50 μg	Anmelden zum Anzeigen	11 bis 14 Tage	$484.00	Details
ABIN4312249	Human	Kaninchen	Unkonjugiert	ELISA, ICC, IF, IHC, IHC (p), WB	0.1 mg	Anmelden zum Anzeigen	8 bis 11 Tage	$488.73	Details
ABIN4312250	Human	Kaninchen	Unkonjugiert	ELISA, ICC, IF, IHC, IHC (p), WB	0.1 mg	Anmelden zum Anzeigen	8 bis 11 Tage	$488.73	Details
ABIN297064	Human	Kaninchen	Unkonjugiert	WB	50 μg	Anmelden zum Anzeigen	11 bis 14 Tage	$551.83	Details
ABIN1734391	Human	Kaninchen	Unkonjugiert	IHC (p), ELISA, WB	50 μg	Anmelden zum Anzeigen	12 bis 14 Tage	$686.14	Details

Weitere Produktkategorien zu FNBP1L Antikörper

Am meisten referenzierte anti-FNBP1L Antikörper

Human Polyclonal FNBP1L Primary Antibody für IHC (p), WB - ABIN541651 : Ho, Rohatgi, Lebensohn, Le Ma, Li, Gygi, Kirschner: Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex. in Cell 2004 (PubMed)
Show all 2 Pubmed References
Human Polyclonal FNBP1L Primary Antibody für IHC (p), WB - ABIN541653 : Kakimoto, Katoh, Negishi: Regulation of neuronal morphology by Toca-1, an F-BAR/EFC protein that induces plasma membrane invagination. in The Journal of biological chemistry 2006 (PubMed)
Show all 2 Pubmed References

Weitere Antikörper gegen FNBP1L Interaktionspartner

Human Formin Binding Protein 1-Like (FNBP1L) Interaktionspartner

This suggests that TOCA1 binding to Cdc42 is an early step in the Cdc42-dependent pathways that govern actin dynamics, and the differential binding affinities of the effectors facilitate a handover from TOCA1 to N-WASP, which can then drive recruitment of the actin-modifying machinery.
Loss of p53 tumor suppressor function in breast cancers leads to upregulation of Toca-1, and results in enhanced risk of developing metastatic disease.
GWAS results show that the aggregate effects of common SNPs explain 22-46% of phenotypic variation in childhood intelligence in the three largest cohorts; FNBP1L was also significantly associated with childhood intelligence
findings suggest that Toca-1 functions at an early step in the dissemination of metastatic breast tumor cells; taken together, results identify Toca-1 as a proinvasive protein in breast adenocarcinoma
Toca-1 knockdown cells also display a significant defect in EGF-induced motility and invasiveness.
Cdc42 may influence endocytic membrane trafficking by regulating the formation and activity of the Toca-1/N-WASP complex.
Toca-1 promotes actin nucleation by activating the N-WASP-WIP/CR16 complex, the predominant form of N-WASP in cells.
a vesicle trafficking regulator Toca-1 regulates different aspects of neuronal morphology from N-WASP
We show that actin tail initiation by S. flexneri requires Toca-1 for the conversion of N-WASP from a closed inactive conformation to an open active one.
the Toca-1-N-WASP complex can link filopodial formation to endocytosis
Human FNBP1L binds the autophagy protein Atg3 and is required for autophagy of Salmonella Typhimurium in epithelial cells

Mouse (Murine) Formin Binding Protein 1-Like (FNBP1L) Interaktionspartner

Toca-1(knockdown) cells have defects in formation of myotubes probably due to reduced activity of actin cytoskeleton regulators such as N-WASP.

Xenopus laevis Formin Binding Protein 1-Like (FNBP1L) Interaktionspartner

This suggests that TOCA1 binding to Cdc42 is an early step in the Cdc42-dependent pathways that govern actin dynamics, and the differential binding affinities of the effectors facilitate a handover from TOCA1 to N-WASP, which can then drive recruitment of the actin-modifying machinery.

FNBP1L Antigen-Profil

Protein Überblick

The protein encoded by this gene binds to both CDC42 and N-WASP. This protein promotes CDC42-induced actin polymerization by activating the N-WASP-WIP complex and, therefore, is involved in a pathway that links cell surface signals to the actin cytoskeleton. Alternative splicing results in multiple transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit FNBP1L

formin binding protein 1 like (FNBP1L) Antikörper
formin binding protein 1-like (Fnbp1l) Antikörper
formin binding protein 1-like (fnbp1l) Antikörper
formin binding protein 1 like (fnbp1l) Antikörper
formin binding protein 1 like L homeolog (fnbp1l.L) Antikörper
formin binding protein 1 like S homeolog (fnbp1l.S) Antikörper

2610318I01Rik Antikörper
AW548221 Antikörper
C1orf39 Antikörper
fnbp1l Antikörper
MGC132162 Antikörper
RGD1305386 Antikörper
toca-1 Antikörper
toca1 Antikörper
zgc:100923 Antikörper

Bezeichner auf Proteinebene für FNBP1L

formin-binding protein 1-like , toca-1 , transducer of Cdc42-dependent actin assembly 1 , transducer of Cdc42-dependent actin assembly protein 1 , Cdc42 effector , formin binding protein 1-like , transducer of Cdc42-dependent actin assembly-1 , Transducer of Cdc42-dependent actin assembly protein 1

GENE ID	SPEZIES
54874	Homo sapiens
214459	Mus musculus
310839	Rattus norvegicus
424495	Gallus gallus
445240	Danio rerio
448740	Xenopus (Silurana) tropicalis
469385	Pan troglodytes
479942	Canis lupus familiaris
616665	Bos taurus
713578	Macaca mulatta
735241	Xenopus laevis
100032840	Monodelphis domestica
100059052	Equus caballus
100077332	Ornithorhynchus anatinus
100157977	Sus scrofa
100338578	Oryctolagus cuniculus
100405015	Callithrix jacchus
100448000	Pongo abelii
100476131	Ailuropoda melanoleuca
100559983	Anolis carolinensis
446802	Xenopus laevis

Ausgewählte Anbieter für anti-FNBP1L (FNBP1L) Antikörper

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