Fc Receptor, IgG, Low Affinity IV Proteine

Receptor for the Fc region of immunoglobulin gamma (PubMed:16039578).

Typ
  • 4
    Protein
Antigen
  • 4
Reaktivität
  • 4
Anwendung
  • 4
  • 3
  • 1
  • 1
  • 1
Wirt
  • 4
Bindungsspezifität
  • 3
  • 1
Konjugat
  • 2
  • 1
  • 1
Protein-Typ
  • 4
Format
  • 4
Biologische Aktivität
  • 3
4 Produkte
Recombinant Protein, Human Cells (Quelle), Reinheit Greater than 95 % as determined by reducing SDS-PAGE.
ReaktivitätMaus
Applikation ELISA, MS, SDS, WB
Bestellinformationen Artikelnr. ABIN5955402
$225.00
10 μg
Zzgl. Versandkosten $45.00
Lieferung in 15 bis 16 Werktagen
Recombinant Protein, Human Cells (Quelle), Reinheit > 95 % as determined by SDS-PAGE
ReaktivitätMaus
Applikation Func, SDS
Bestellinformationen Artikelnr. ABIN2007202
ISO
$440.65
Zzgl. Versandkosten $45.00
Lieferung in 14 bis 16 Werktagen
Recombinant Protein, Human Cells (Quelle), Reinheit > 97 % as determined by SDS-PAGE
ReaktivitätMaus
Applikation Func, SDS
Bestellinformationen Artikelnr. ABIN2007204
ISO
$440.65
Zzgl. Versandkosten $45.00
Lieferung in 14 bis 16 Werktagen
Recombinant Protein, Human Cells (Quelle), Reinheit > 95 % as determined by SDS-PAGE
ReaktivitätMaus
Applikation Func, SDS
Bestellinformationen Artikelnr. ABIN2007207
ISO
$440.65
Zzgl. Versandkosten $45.00
Lieferung in 14 bis 16 Werktagen
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Fc Receptor, IgG, Low Affinity IV (FCGR4) Protein Überblick

Protein Überblick

Receptor for the Fc region of immunoglobulin gamma (PubMed:16039578). Also acts as a receptor for the Fc region of immunoglobulin epsilon (PubMed:17558411, PubMed:18949059). Binds with intermediate affinity to both IgG2a and IgG2b (PubMed:16039578, PubMed:17558411, PubMed:19795417). Can bind to IgG2a and IgG2b monomers (PubMed:18949059). Does not display binding to IgG1 or IgG3 (PubMed:16039578). Mediates neutrophil activation by IgG complexes redundantly with Fcgr3 (PubMed:18097064). Plays a role in promoting bone resorption by enhancing osteoclast differentiation following binding to IgG2a (PubMed:25824719). Binds with low affinity to both the a and b allotypes of IgE (PubMed:18949059). Has also been shown to bind to IgE allotype a only but not to allotype b (PubMed:17558411). Binds aggregated IgE but not the monomeric form and bound monomeric IgG is readily displaced by IgE complexes (PubMed:18949059). Binding to IgE promotes macrophage-mediated phagocytosis, antigen presentation to T cells, production of proinflammatory cytokines and the late phase of cutaneous allergic reactions (PubMed:17558411, PubMed:18949059). {ECO:0000269|PubMed:16039578, ECO:0000269|PubMed:17558411, ECO:0000269|PubMed:18097064, ECO:0000269|PubMed:18949059, ECO:0000269|PubMed:19795417, ECO:0000269|PubMed:25824719}.

Genbezeichner und Symbole assoziert mit FCGR4

  • Fc receptor, IgG, low affinity IV (Fcgr4) Antikörper
  • 4833442P21Rik Antikörper
  • CD16-2 Antikörper
  • FcgammaRIV Antikörper
  • Fcgr3a Antikörper
  • FcgRIV Antikörper
  • Fcrl3 Antikörper

Bezeichner auf Proteinebene für FCGR4

CD16-2 , Fc fragment of IgG, low affinity IIIa, receptor for (CD16); Fc fragment of IgG, low affinity III, receptor for (CD16) , Fc gammaRIV , Fc receptor-like 3 , FcgammaRIV , low affinity immunoglobulin gamma Fc region receptor III-A , low affinity immunoglobulin gamma Fc region receptor IV

GENE ID SPEZIES
246256 Mus musculus
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