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FCAR is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. Zusätzlich bieten wir Ihnen Fc Fragment of IgA, Receptor For Antikörper (189) und Fc Fragment of IgA, Receptor For Proteine (14) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 28 products:
Human FCAR ELISA Kit für Sandwich ELISA - ABIN417632
Moresco, Speeckaert, Zmonarski, Krajewska, Komuda-Leszek, Perkowska-Ptasinska, Gesualdo, Rocchetti, Delanghe, Vanholder, Van Biesen, Delanghe: Urinary myeloid IgA Fc alpha receptor (CD89) and transglutaminase-2 as new biomarkers for active IgA nephropathy and henoch-Schönlein purpura nephritis. in BBA clinical 2016
have mapped the IgA (zeige IgA ELISA Kits) binding site of bovine IgA Fc receptor and show that, in common with CD89, Tyr (zeige TYR ELISA Kits)-35 in the B-C loop is essential for IgA (zeige IgA ELISA Kits) binding
In transgenic mice, IgAN pathogenesis involves impaired clearance of abnormal IgA (zeige IgA ELISA Kits) via CD89, primarily by the Kupffer cells. Conditional IgAN progression in CD89 transgenic mice thus reveals important aspects of IgAN pathogenesis.
a novel Fcar splice variant termed variant APD isolated from a healthy volunteer that lacks only the IgA (zeige IgA ELISA Kits)-binding EC1 domain, is reported.
Findings suggest a basis for the use of Fc receptor I for IgA (zeige IgA ELISA Kits) (FcalphaRI) as a molecular target for the treatment of lupus.
this study examined the expression of IL-4 (zeige IL4 ELISA Kits) mRNA, IFN-c mRNA and FcaRI mRNA in tonsillar mononuclear cells of IgA (zeige IgA ELISA Kits) nephropathy9(IgAN) patients and non-IgAN patients.
FCAR polymorphism is not associated with high susceptibility to IGA (zeige IgA ELISA Kits) nephropathy in caucasians.
Abnormally glycosylated IgA1 and soluble CD89-IgA (zeige IgA ELISA Kits) and IgA (zeige IgA ELISA Kits)-IgG complexes, features of primary IgA (zeige IgA ELISA Kits) nephropathy, are also present in alcoholic cirrhosis.
Genetic variation at the promoter region of IgA (zeige IgA ELISA Kits) receptor is associated with IgA (zeige IgA ELISA Kits) nephropathy.
These results suggest a role of anti-FcaRI Fab as a negative regulator in controlling the magnitude of the innate immune response
Glycosylation of the CH2/CH3 (zeige SOX3 ELISA Kits) interface inhibits interaction with the pathogen IgA (zeige IgA ELISA Kits) binding protein SSL7, while maintaining binding of pIgR (zeige PIGR ELISA Kits), essential to the biosynthesis and transport of SIgA.
There is an association between the levels of sCD89-IgA (zeige IgA ELISA Kits) complexes in serum and the severity of IgA (zeige IgA ELISA Kits) nephropathy, and a possible genetic component in regulating the production or expression of sCD89.
This gene is a member of the immunoglobulin gene superfamily and encodes a receptor for the Fc region of IgA. The receptor is a transmembrane glycoprotein present on the surface of myeloid lineage cells such as neutrophils, monocytes, macrophages, and eosinophils, where it mediates immunologic responses to pathogens. It interacts with IgA-opsonized targets and triggers several immunologic defense processes, including phagocytosis, antibody-dependent cell-mediated cytotoxicity, and stimulation of the release of inflammatory mediators. Multiple alternatively spliced transcript variants encoding different isoforms have been described for this gene.
IgA Fc receptor
, immunoglobulin A Fc receptor
, immunoglobulin alpha Fc receptor
, Fc fragment of IgA, receptor for, isoform 7
, Fc alpha receptor