FOS-Like Antigen 1 Proteine (FOSL1)

The Fos gene family consists of 4 members FOSL1, and FOSL2. Zusätzlich bieten wir Ihnen FOSL1 Antikörper (101) und FOSL1 Kits (22) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
FOSL1 8061 P15407
FOSL1 14283 P48755
FOSL1 25445 P10158
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Top FOSL1 Proteine auf

Showing 8 out of 10 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Escherichia coli (E. coli) Human His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Ratte His tag,GST tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Escherichia coli (E. coli) Maus His tag,T7 tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage

FOSL1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, , ,
Mouse (Murine) ,
Rat (Rattus) ,

Weitere Proteine zu FOS-Like Antigen 1 (FOSL1) Interaktionspartnern

Human FOS-Like Antigen 1 (FOSL1) Interaktionspartner

  1. Fra1 inhibited the protein levels of Bcl2 (zeige BCL2 Proteine), cMyc (zeige MYC Proteine), Survivin, and BclxL (zeige BCL2L1 Proteine). Fra1 overexpression in intestinal mucosal epithelial cells may restrain damage repair after intestinal mucosal injury in inflammatory bowel disease remittent period through weakening the protective effect of intestinal mucosa, thus increasing the risk of recurrence.

  2. High FRA1 expression is associated with Esophageal Squamous Cell Carcinoma.

  3. constitutive activation and non-regulation of Fra-1 by bicalutamide in PC-3 (zeige PCSK1 Proteine) cells suggested that Fra-1, probably a key component, involved in transition of aggressive androgen-independent PC-3 (zeige PCSK1 Proteine) cells with poor prognosis.

  4. the overexpression of Fra1 disrupted inflammatory cytokine secretion by medullary thymic epithelial cells in the myasthenia gravis thymus

  5. Taken together, our results indicated that miR (zeige MLXIP Proteine)-449 overexpression inhibited osteogenic differentiation of HG-FFA-treated hBMSCs through the Sirt1 (zeige SIRT1 Proteine)/Fra-1 signal pathway.

  6. These findings indicate that an aberrant Wnt (zeige WNT2 Proteine)/beta-catenin (zeige CTNNB1 Proteine) signalling leads to the epithelial-mesenchymal transition and drug resistance of glioma via Fra1 induction, which suggests novel therapeutic strategies for the malignant disease.

  7. MUC1 (zeige MUC1 Proteine) enhancement of ERK (zeige EPHB2 Proteine) activation influences FRA-1 activity to modulate tumor migration, invasion and metastasis in a subset of pancreatic cancer cases

  8. the results indicate that FRA1 promotes cancer growth through AKT (zeige AKT1 Proteine), and enhances cancer cell migration through JNK/c-Jun, pinpointing FRA1 as a key integrator of JNK (zeige MAPK8 Proteine) and AKT (zeige AKT1 Proteine) signaling pathways and a potential therapeutic target for squamous cell carcinoma of the skin and head and neck squamous cell carcinoma.

  9. Study shows that FOSL1 is the main immediate early AP-1 (zeige JUN Proteine) member induced by melanoma oncogenes; found that FOSL1 is involved in melanoma cell migration as well as cell proliferation and anoikis-independent growth.

  10. a Fra-1-miR (zeige MLXIP Proteine)-134 axis drives a positive feedback loop that amplifies ERK (zeige EPHB2 Proteine)/JNK (zeige MAPK8 Proteine) signaling and reduces chemosensitivity in ovarian cancer cells.

Mouse (Murine) FOS-Like Antigen 1 (FOSL1) Interaktionspartner

  1. NF-kappaB (zeige NFKB1 Proteine) and c-Jun (zeige JUN Proteine) coregulate lipopolysaccharide-induced Fra-1 transcription.

  2. Upon stimulation with poly(I:C), malaria parasite-infected red blood cells (iRBCs), or vesicular stomatitis virus (VSV), FOSL1 "translocated" from the nucleus to the cytoplasm, where it inhibited the interactions between TNF receptor-associated factor 3 (TRAF3 (zeige TRAF3 Proteine)), TIR domain-containing adapter inducing IFN-beta (zeige IFNB1 Proteine) (TRIF (zeige RNF138 Proteine)), and Tank-binding kinase 1 (TBK1 (zeige TBK1 Proteine)) via impairing K63-linked polyubiquitination of TRAF3 (zeige TRAF3 Proteine) and TRIF (zeige RNF138 Proteine).

  3. Adipose-derived stromal cells overexpressing Fra-1 effectively protect against osteoarthritis.

  4. Overexpression of Fosl1, which encodes a component of the AP-1 (zeige JUN Proteine) transcription factor complex, in osteoblasts significantly blocked malleal capillary narrowing.

  5. Fra-1 gene expression is activated in response lipopolysaccharide induced lung-injury in mice.

  6. Data suggest that expression of Fra1 (fos-related antigen 1) in preadipocytes is up-regulated by arachidonic acid (AA) during late stages of adipogenesis; however, in early stage of adipogenesis, AA inhibits adipogenesis via Fra1-dependent mechanism.

  7. Fra-1 plays a key role in promoting chronic CS-induced lung macrophagic inflammation in vivo

  8. we demonstrate that Fra1 negatively controls plasma cell differentiation by repressing Blimp1 (zeige PRDM1 Proteine) expression.

  9. observations suggest that MyoD (zeige MYOD1 Proteine) and pRb (zeige PGR Proteine) work together cooperatively at the level of the intronic enhancer of Fra-1 during terminal cell cycle arrest

  10. findings, based on a definitive genetic mouse model provide fundamental insights into mammary duct maturation and homeostasis and reveal that Scrib (zeige SCRIB Proteine) loss activates a MAPK (zeige MAPK1 Proteine)/Fra1 pathway that alters mammary progenitor activity

FOSL1 Protein Überblick

Protein Überblick

The Fos gene family consists of 4 members FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation.

Genbezeichner und Symbole assoziert mit FOS-Like Antigen 1 Proteine (FOSL1)

  • FOS like 1, AP-1 transcription factor subunit (FOSL1)
  • fos-like antigen 1 (Fosl1)
  • FOS like 1, AP-1 transcription factor subunit (Fosl1)
  • FOS-like antigen 1a (fosl1a)
  • AW538199 Protein
  • fosl1 Protein
  • FRA Protein
  • Fra-1 Protein
  • Fra1 Protein
  • sb:eu506 Protein
  • si:ch211-145o7.4 Protein

Bezeichner auf Proteinebene für FOS-Like Antigen 1 Proteine (FOSL1)

FOS-like antigen-1 , fos-related antigen 1 , FOS-like antigen 1

8061 Homo sapiens
483724 Canis lupus familiaris
531389 Bos taurus
14283 Mus musculus
25445 Rattus norvegicus
100734428 Cavia porcellus
101111137 Ovis aries
564241 Danio rerio
Ausgewählte Anbieter für FOSL1 Proteine (FOSL1)
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