Endogenous Retrovirus Group W, Member 1 Proteine (ERVW-1)

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. Zusätzlich bieten wir Ihnen ERVW-1 Antikörper (42) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
ERVW-1 30816 Q9UQF0
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Top ERVW-1 Proteine auf antikoerper-online.de

Showing 2 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,749.58
Details
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
Details

ERVW-1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
, ,

Am meisten referenzierte ERVW-1 Proteine

  1. Human ERVW-1 Protein expressed in Wheat germ - ABIN1353105 : Holder, Tower, Forbes, Mulla, Aplin, Abrahams: Immune cell activation by trophoblast-derived microvesicles is mediated by syncytin 1. in Immunology 2012 (PubMed)

Weitere Proteine zu Endogenous Retrovirus Group W, Member 1 (ERVW-1) Interaktionspartnern

Human Endogenous Retrovirus Group W, Member 1 (ERVW-1) Interaktionspartner

  1. These data revealed that human endogenous retrovirus W env might contribute to increase nitric oxide production and microglial migration ability in neuropsychological disorders by regulating the expression of inducible nitric oxide synthase.

  2. CD47 seems to mediate fusion mostly through broad contact surfaces between the partners' cell membrane while syncytin-1 mediate fusion through phagocytic-cup like structure.

  3. HERV-W was expressed in demyelinated lesions from multiple sclerosis brains, which were all positive for this endogenous pathogenic protein. Pronounced HERV-W immunoreactivity in active multiple sclerosis lesions was intimately associated with areas of active demyelination throughout the successive stages of lesion evolution in multiple sclerosis brains.

  4. ERVWE1, ERVFRDE1 and ERV3 transcription was down-regulated in hydatidiform moles and gestational trophoblastic neoplasia.

  5. Study found no associations between embroynal ERVW-1 polymorphisms and preeclampsia.

  6. Identification of the two CpG dinucleotides around transcription start site as key epigenetic elements has provided valuable information for further studies on the epigenetic regulation of syncytin-1 in pancreatic cancer cells

  7. Positive associations were observed between HERV-w methylation and dietary intakes of beta-carotene and carotenoids in a population of obese subjects.

  8. Syncytin-1 and ASCT-2 is localized at the acrosomal region and equatorial segment of the spermatozoa.

  9. Data show that Multiple Sclerosis-Associated Retrovirus (MSRV) is predominantly expressed over ERWVE1 in astrocyte-derived U-87 glioblastoma cell line.

  10. The effect of ETS1 on syncytialization of trophoblasts likely results, at least in part, from inhibition of syncytin expression.

  11. These results indicated that aberrant hypermethylation is involved in downregulation of syncytin-1, and epigenetic alterations may play a significant role in the development of preeclampsia

  12. Exosomes from cultured primary villous cytotrophoblasts and sera of pregnant women have syncytin-1 on their surfaces. It acts on cellular binding and uptake of exosomes.

  13. Increased trophoblast apoptosis and altered expression levels of syncytin-1, calpain 1, and AIF is observed in preeclamptic placentas.

  14. Syncytin-1 overexpression may be an indicator of urothelial cell carcinoma risk.

  15. Insertionally polymorphic HERV-K113 and HERV-K115 are not associated with HIV infections.

  16. Influenza A virus infection transactivated ERVWE1 by increasing the transcription of GCM1.

  17. Overexpression of HERV-W envelope gene elevated the levels of SK3 channel in neuroblastoma cells.

  18. Syncytin-1 knockdown significantly inhibited BeWo cell growth and DNA synthesis and Syncytin-1 could promote the G1/S transition through p15 and CDK4.

  19. In discordant monozygotic twins, HERVWE1 expression is higher in smaller fetuses and lower in larger counterparts. Methylation of the HERVWE1 gene promoter region may participate in gene regulation.

  20. This study linked decreased Syncytin-1 expression to an epigenetic hypermethylation of the entire promoter of ERVW-1.

ERVW-1 Protein Überblick

Protein Überblick

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 7 that has inactivating mutations in the gag and pol genes. This gene is the envelope glycoprotein gene which appears to have been selectively preserved. The gene's protein product is expressed in the placental syncytiotrophoblast and is involved in fusion of the cytotrophoblast cells to form the syncytial layer of the placenta. The protein has the characteristics of a typical retroviral envelope protein, including a furin cleavage site that separates the surface (SU) and transmembrane (TM) proteins which form a heterodimer. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

Genbezeichner und Symbole assoziert mit ERVW-1

  • endogenous retrovirus group W member 1, envelope (ERVW-1)
  • ENV Protein
  • ENVW Protein
  • ERVWE1 Protein
  • HERV-7q Protein
  • HERV-W-ENV Protein
  • HERV7Q Protein
  • HERVW Protein
  • HERVWENV Protein

Bezeichner auf Proteinebene für ERVW-1

HERV-7q envelope protein , HERV-W Env glycoprotein , HERV-W envelope protein , HERV-W_7q21.2 provirus ancestral Env polyprotein , HERV-W{7q21.1} provirus ancestral Env polyprotein , HERV-tryptophan envelope protein , endogenous retroviral family W, env(C7), member 1 , endogenous retrovirus group W member 1 , env-W , envelope glycoprotein , envelope polyprotein gPr73 , envelope protein , enverin , human endogenous retrovirus W envC7-1 envelope protein , syncytin A , syncytin-1

GENE ID SPEZIES
30816 Homo sapiens
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