anti-Dual Specificity Phosphatase 1 (DUSP1) Antikörper

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. Zusätzlich bieten wir Ihnen DUSP1 Kits (29) und DUSP1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DUSP1 1843 P28562
DUSP1 19252 P28563
DUSP1 114856 Q64623
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Top anti-DUSP1 Antikörper auf

Showing 10 out of 111 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN184638 (3.8µg/ml) staining of paraffin embedded Human Prostate. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. ABIN184638 (0.3µg/ml) staining of HeLa lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
Huhn Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of DUSP1 staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of DUSP1 expression in HeLa (A) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from Jurkat cells, using MKP1 (Ab-359) Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human brain tissue, using MKP1 (Ab-359) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human lung carcinoma, using MKP1 (Phospho-Ser359) Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert EIA, WB 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
Rind (Kuh) Ziege Unkonjugiert IHC (p), WB   0.1 mg Anmelden zum Anzeigen 12 bis 15 Tage
Human Kaninchen Unkonjugiert IF, WB The anti-DUSP1 Pab (ABIN392905) is used in Western blot to detect DUSP1 in 293 cell lysate. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Ziege Unkonjugiert EIA, IHC (p), WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse lymphoma tissue labeled with Anti-DUSP1/MKP-1 Polyclonal Antibody, Unconjugated (ABIN735368) at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
Fledermaus Ziege Unkonjugiert IHC (p), ELISA, WB Human Prostate (formalin-fixed, paraffin-embedded) stained with DUSP1 antibody ABIN351458 at 3.75 ug/ml followed by biotinylated anti-goat IgG secondary antibody ABIN481715, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 7 bis 9 Tage

DUSP1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-DUSP1 Antikörper

  1. Human Polyclonal DUSP1 Primary Antibody für IF (p), IHC (p) - ABIN735368 : Kato, Naiki-Ito, Naiki, Suzuki, Yamashita, Sato, Sagawa, Kato, Kuno, Takahashi: Connexin 32 dysfunction promotes ethanol-related hepatocarcinogenesis via activation of Dusp1-Erk axis. in Oncotarget 2016 (PubMed)
    Show all 2 Pubmed References

  2. Human Polyclonal DUSP1 Primary Antibody für IF (p) - ABIN894519 : Khadir, Tiss, Abubaker, Abufarha, Al-Khairi, Cherian, John, Kavalakatt, Warsame, Al-Madhoun, Al-Ghimlas, Elkum, Behbehani, Dermime, Dehbi: MAP kinase phosphatase DUSP1 is overexpressed in human obese and modulated by physical activity. in American journal of physiology. Endocrinology and metabolism 2014 (PubMed)

  3. Human Monoclonal DUSP1 Primary Antibody für IF, ELISA - ABIN515099 : Chao, Sun, Peng, Wu: Growth Hormone Releasing Peptide-2 Attenuation of Protein Kinase C-Induced Inflammation in Human Ovarian Granulosa Cells. in International journal of molecular sciences 2016 (PubMed)

  4. Human Polyclonal DUSP1 Primary Antibody für IHC (p), IHC - ABIN257653 : Alessi, Smythe, Keyse: The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts. in Oncogene 1993 (PubMed)

Weitere Antikörper gegen DUSP1 Interaktionspartner

Human Dual Specificity Phosphatase 1 (DUSP1) Interaktionspartner

  1. We propose a signaling cascade involving ARID1A (zeige ARID1A Antikörper), GADD45B (zeige GADD45B Antikörper) and DUSP1 as mediators of the romidepsin effects in GCC (zeige GUCY2C Antikörper) cells.

  2. this work indicates that suppression of JNK1 (zeige MAPK8 Antikörper)/2 activity by MKP-1 maintains PARP-1 (zeige PARP1 Antikörper) levels and suggests that MKP-1-mediated cisplatin resistance can be bypassed by PARP-1 (zeige PARP1 Antikörper) inhibition.

  3. Mean morning and evening DUSP1 mRNA levels showed significant increase during Ramadan compared to Shabaan, however, its diurnal rhythm was maintained. Morning IL-1alpha mRNA expression remained significantly higher than in the evening during Ramadan, but was markedly decreased compared to Shabaan.

  4. Methylation-mediated silencing of the DUSP-1 promoter does not appear to be associated with reduced expression, indicating the involvement of other factors in specific suppression of DUSP-1 in diabetes-associated cardiac hypertrophy.

  5. Increased MAP2K6 (zeige MAP2K6 Antikörper), MAP4K3 (zeige MAP4K3 Antikörper), and DUSP1 gene expressions in post-chemotherapy samples indicate a poor clinical outcome in osteosarcoma patients.

  6. The aim of this review is to shed light on the role of four different phosphatases (PTEN, PP2A (zeige PPP2R4 Antikörper), CDC25 (zeige RASGRF1 Antikörper) and DUSP1) in five different solid tumors (breast cancer, lung cancer, pancreatic cancer, prostate cancer and ovarian cancer), in order to better understand the most frequent and aggressive primary cancer of the central nervous system, glioblastoma.

  7. Dual-specific phosphatase (DUSP1) was found to inhibit gallbladder cancer (GBC) cell proliferation, migration and invasion.

  8. The results presented here emphasize the importance of MKP-1 as a mediator of therapeutic effects of glucocorticoids in inflammatory lung diseases as well as its potential as a novel anti-inflammatory drug target.

  9. we show that IL-1 (zeige IL1A Antikörper) induces robust p38a (zeige MAPK14 Antikörper) activation both in the nucleus and in the cytoplasm/membrane.Following stimulation, p38a (zeige MAPK14 Antikörper) activity returns to a basal level in absence of receptor degradation. While nuclear pulse is controlled by MKP1 through a negative feedback to pp38, its basal activity is controlled by both TAB1 (zeige TAB1 Antikörper) and MKP1 through a positive feedback loop.

  10. Our results emphasize the importance of MKP-1 as a potential predictive biomarker for a subset of breast cancer patients with worse outcome and less susceptibility to treatment.

Mouse (Murine) Dual Specificity Phosphatase 1 (DUSP1) Interaktionspartner

  1. these data show that MKP-1 is an important endogenous suppressor of innate immune responses involved in the regulation of blood-testis barrier barrier dynamic

  2. MKP-1 regulates IL-1beta (zeige IL1B Antikörper) production through stabilization of HIF-1alpha (zeige HIF1A Antikörper). The induction of HIF-1alpha (zeige HIF1A Antikörper) protein in MKP-1 deficiency is partly due to p38MAPK (zeige MAPK14 Antikörper) activation in response to LPS (zeige TLR4 Antikörper).

  3. this work identifies a previously unrecognized role for DUSP1 in regulating autophagy.

  4. c-FOS and DUSP1 expression levels determine the threshold of tyrosine kinase (zeige TYRO3 Antikörper) inhibitor (TKI) efficacy, such that growth-factor-induced expression of c-FOS and DUSP1 confers intrinsic resistance to TKI therapy in a wide-ranging set of leukemias.

  5. PTHrP counteracts the pro-apoptotic actions of reactive oxygen species by a mechanism dependent on MKP1-induced dephosphorylation.

  6. A2AR (zeige ADORA2A Antikörper) signaling regulates both basal and LPS (zeige TLR4 Antikörper)-induced DUSP1 levels in macrophages via activating the adenylate cyclase pathway.

  7. these data suggest an important role for DUSPs in regulating MAPK (zeige MAPK1 Antikörper) dephosphorylation, with an emphasis on DUSP1, during early adipogenesis

  8. Loss of DUSP1 does not cause changes in cartilage degeneration and gait in a mouse model of spontaneous osteoarthritis at 21 months of age.

  9. Nr4a1 (zeige NR4A1 Antikörper) induction is dependent on ERK1/2 and that MKP-1 negatively regulates this induction.

  10. MKP-1 negatively regulates chemokine (zeige CCL1 Antikörper)-driven osteoclast formation and subsequent bone resorption in response to LPS (zeige TLR4 Antikörper) stimulation

Cow (Bovine) Dual Specificity Phosphatase 1 (DUSP1) Interaktionspartner

  1. MKP-1 is the specific phosphatase induced by AngII and involved in the negative feedback mechanism ensuring adequate ERK1/2-mediated aldosterone production in response to the hormone.

Pig (Porcine) Dual Specificity Phosphatase 1 (DUSP1) Interaktionspartner

  1. Agonist stimulation of vascular smooth muscle increases PKC (zeige FYN Antikörper) activity, which, in turn, increases MKP-1 activity and maintains MAPK1 (zeige MAPK1 Antikörper) activity at submaximal values.

DUSP1 Antigen-Profil

Protein Überblick

The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.

Genbezeichner und Symbole assoziert mit DUSP1

  • dual specificity phosphatase 1 (DUSP1) Antikörper
  • dual specificity phosphatase 1 (dusp1) Antikörper
  • dual specificity phosphatase 1 (Dusp1) Antikörper
  • 3CH134 Antikörper
  • cb269 Antikörper
  • CL100 Antikörper
  • DUSP1 Antikörper
  • erp Antikörper
  • HVH1 Antikörper
  • id:ibd2586 Antikörper
  • mkp-1 Antikörper
  • Mkp1 Antikörper
  • PTPN10 Antikörper
  • Ptpn16 Antikörper
  • sb:cb269 Antikörper
  • U19515 Antikörper
  • wu:fd19g02 Antikörper
  • wu:fe50g09 Antikörper
  • zgc:55920 Antikörper

Bezeichner auf Proteinebene für DUSP1

dual specificity protein phosphatase 1 , dual specificity phosphatase 1 , mkp-1 , MAP kinase phosphatase 1 , dual specificity protein phosphatase hVH1 , mitogen-activated protein kinase phosphatase 1 , protein-tyrosine phosphatase CL100 , serine/threonine specific protein phosphatase , mitogen-activated protein kinase phosphatase-1 , protein tyrosine phosphatase, non-receptor type 16 , protein-tyrosine phosphatase 3CH134 , protein-tyrosine phosphatase ERP , 3CH134/CL100 PTPase , MAP kinase phosphatase-1 , mitogen-activated protein (MAP) kinase phosphatase-1 , oxidative stress-inducible protein tyrosine phosphatase , protein tyrosine phosphatase non-receptor type 16 , protein-tyrosine phosphatase non-receptor type 16 , MAPK phosphatase 1

374192 Gallus gallus
471742 Pan troglodytes
100219518 Taeniopygia guttata
100340993 Oryctolagus cuniculus
406340 Danio rerio
1843 Homo sapiens
19252 Mus musculus
114856 Rattus norvegicus
489117 Canis lupus familiaris
539175 Bos taurus
100522469 Sus scrofa
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