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DNAJB6 encodes a member of the DNAJ protein family. Zusätzlich bieten wir Ihnen DnaJ (Hsp40) Homolog, Subfamily B, Member 6 Proteine (17) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 94 products:
Human Monoclonal DNAJB6 Primary Antibody für IF, ELISA - ABIN564339
De Bock, Lin, Mekkawy, Byrne, Wang: Interaction between urokinase receptor and heat shock protein MRJ enhances cell adhesion. in International journal of oncology 2010
Human Polyclonal DNAJB6 Primary Antibody für IF, WB - ABIN523418
Mitra, Rostas, Dyess, Shevde, Samant: Micro-RNA-632 downregulates DNAJB6 in breast cancer. in Laboratory investigation; a journal of technical methods and pathology 2012
Human Polyclonal DNAJB6 Primary Antibody für ICC, IF - ABIN4305595
Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013
Chlamydomonas reinhardtii (C. reinhardtii) Polyclonal DNAJB6 Primary Antibody für WB - ABIN1027728
Pellecchia, Szyperski, Wall, Georgopoulos, Wüthrich: NMR structure of the J-domain and the Gly/Phe-rich region of the Escherichia coli DnaJ chaperone. in Journal of molecular biology 1996
Show all 4 Pubmed References
Expression of the heat shock protein DNAJB6/MRJ was elevated in neutrophils and lymphocytes of patients with atopic dermatitis compared with healthy donors. The highest level of the DNAJB6/MRJ protein was found to be in neutrophils at acute phase of severe atopic dermatitis and gradually decline as continue to the disease.
mRNA levels of HSP family members (HSP70B', HSP72 (zeige HSPA1A Antikörper), HSP40/DNAJ (zeige DNAJB1 Antikörper), and HSP20 (zeige HSPB6 Antikörper)/CRYAB (zeige CRYAB Antikörper)) are upregulated by the intracellular MMP3 (zeige MMP3 Antikörper) overload.
the cytoprotective effects of DNAJB6(S) may be mediated, at least in part, by the mitochondrial pathway of apoptosis.
The results indicate both genetic and physical interactions between disease-linked RNA-binding proteinss and DNAJB6/mrj, suggesting etiologic overlap between the pathogenesis of adult-onset inherited myopathies initiated by mutations in hnRNPA2B1 (zeige HNRNPA2B1 Antikörper) and DNAJB6.
LGMD1D mutations in DNAJB6 disrupt its sarcoplasmic function suggesting a role for DNAJB6b in Z-disc organization and stress granule kinetics.
DNAJB6 mutations p.F91I and p.F91L show a significant reduction of the anti-aggregation function compared to the wild-type and p.F93L mutation
DnaJB6-protected yeast cells from polyglutamine toxicity and cured yeast of both [URE3] prions and weak variants of [PSI(+)] prions but not strong [PSI(+)] prions
This study showed that Complete loss of the DNAJB6 G/F domain and novel missense mutations cause distal-onset DNAJB6 myopathy.
DNAJB6a reduces AKT (zeige AKT1 Antikörper) signaling, and DNAJB6 expression in cancer cells reduces their proliferation and growth of xenograft esophageal squamous cell tumors in mice.
There was a positive correlation between DNAJB6 and IQGAP1 (zeige IQGAP1 Antikörper) expression.
Mrj(-/-) chorions at embryonic day 8.5 have expanded Rhox4b expression domains and do not form normal layers of gene expression suggesting that chorion patterning requires Mrj.
Data show that Mrj(-/-) embryos exhibit neural tube defects independent of the placenta phenotype, including exencephaly and thin-walled neural tubes, and suggest that Mrj plays an important role in neural stem cell self-renewal.
NFATc3 (zeige NFATC3 Antikörper) is negatively regulated by class II histone deacetylases through the DnaJ (zeige DNAJA2 Antikörper) (heat shock protein-40 (zeige DNAJB1 Antikörper)) superfamily member Mrj
Study demonstrates here that, in the developing placenta of the mouse, the absence of the Mrj co-chaperone prevents proteasome degradation of keratin 18 intermediate filaments, resulting in the formation of keratin inclusion bodies.
DnaJB6 is necessary for translocation of Slfn1 into the nucleus, where Slfn1 down-regulates cyclin D1 (zeige CCND1 Antikörper), induces cell-cycle arrest and programmes a quiescent state of T-cells
This gene encodes a member of the DNAJ protein family. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. This family member may also play a role in polyglutamine aggregation in specific neurons. Alternative splicing of this gene results in multiple transcript variants\; however, not all variants have been fully described.
dnaJ homolog subfamily B member 6-B
, DnaJ-like 2 protein
, dnaJ homolog subfamily B member 6
, heat shock protein J2
, mammalian relative of DnaJ
, hsp40 homolog