anti-Dishevelled, Dsh Homolog 3 (Drosophila) (DVL3) Antikörper

DVL3 is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. Zusätzlich bieten wir Ihnen DVL3 Proteine (6) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DVL3 13544 Q61062
DVL3 1857 Q92997
DVL3 303811  
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Top anti-DVL3 Antikörper auf

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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF, IHC (p), WB DVL3 Antibody (C-term)  western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the DVL3 antibody detected the DVL3 protein (arrow). DVL3 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of DVL3 Antibody (C-term) for immunohistochemistry.  Clinical relevance has not been evaluated. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Kaninchen Unkonjugiert WB Western blot analysis of Dishevelled 3 expression in HEK293T (A), Raw264.7 (B), rat kidney (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
Maus Kaninchen Unkonjugiert WB Western blot analysis of Dishevelled 3 using anti- Dishevelled 3 antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: rat brain tissue lysates,   Lane 2: mouse brain tissue lysates.  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti- Dishevelled 3 antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for Dishevelled 3 at approximately 78KD. The expected band size for Dishevelled 3 is at 78KD. 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
Human Kaninchen Unkonjugiert IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using DVL3 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), IHC, WB ICC/IF Image Dishevelled 3 antibody [N1N2], N-term detects Dishevelled 3 protein at cytoplasm by immunofluorescent analysis. Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: Dishevelled 3 protein stained by Dishevelled 3 antibody [N1N2], N-term , diluted at 1:500. Red: phalloidin, a cytoskeleton marker, stained by phalloidin (invitrogen, A12380) diluted at 1:200. Blue: Hoechst 33342 staining. WB Image Sample (30 ug of whole cell lysate) A: HCT116 7.5% SDS PAGE antibody diluted at 1:10000 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p) 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, WB Western blot analysis of extracts from Jurkat cells, using DVL3 antibody.The lane on the left is treated with the antigen-specific peptide. ABIN6275519 staining  Hela cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
Human Kaninchen Unkonjugiert EIA, IF, IHC (p), WB   0.4 mL Anmelden zum Anzeigen 8 bis 11 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunohistochemistry: Dishevelled-3 Antibody [NBP2-38846] - Staining of human pancreas shows strong cytoplasmic positivity in exocrine glandular cells. Western Blot: Dishevelled-3 Antibody [NBP2-38846] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: RT-4.Lane 3: U-251 MG 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage

Weitere Antikörper gegen DVL3 Interaktionspartner

Xenopus laevis Dishevelled, Dsh Homolog 3 (Drosophila) (DVL3) Interaktionspartner

  1. Different Dvl (zeige DVL2 Antikörper) proteins (Dvl1 (zeige DVL1 Antikörper), Dvl2 (zeige DVL2 Antikörper), Dvl3) and the composition of dishevelled (zeige DVL2 Antikörper)-beta-arrestin protein complexes contribute to the specific activation of individual branches of Wnt (zeige WNT2 Antikörper) signaling in Xenopus gastrulation.

  2. Data show that maternal Dvl2 (zeige DVL2 Antikörper) and 3 are required for convergence extension movements downstream of the dorsally localized signaling pathway activated by Xnr3, but not downstream of the pathway activated by activin (zeige Actbeta Antikörper).

Mouse (Murine) Dishevelled, Dsh Homolog 3 (Drosophila) (DVL3) Interaktionspartner

  1. Dvl-2 (zeige DVL2 Antikörper) and Dvl-3 have a widespread distribution in both the olfactory epithelium and olfactory bulb

  2. Dvl3 is important for IPMK (zeige IPMK Antikörper) to access substrates and generate IP5, activating down-stream signaling.

  3. Dishevelled (zeige DVL2 Antikörper)-KSRP (zeige KHSRP Antikörper) complex operates in Wnt (zeige WNT2 Antikörper) regulation of beta-catenin (zeige CTNNB1 Antikörper), functioning post-transcriptionally upon CTNNB1 (zeige CTNNB1 Antikörper) mRNA stability.

  4. Dvl2 (zeige DVL2 Antikörper) and Dvl3 proteins were found to be localized to the apical side of the node cells, and their location was polarized to the posterior side of the cells before the posterior positioning of the basal body.

  5. As embryos reach blastocyst stage, Dishevelled 2 (zeige DVL2 Antikörper) becomes increasingly associated with cell membrane in trophectoderm cells, while at E4.5, Dishevelled 3 is highly enriched in the cytoplasm of inner cell mass cells.

  6. The expression of Dishevelleds in mammalian cells provide an estimate of the relative cellular abundance of each Dvl (zeige DVL1 Antikörper).

  7. G alpha o (zeige GNAO1 Antikörper) mediates WNT (zeige WNT2 Antikörper)-JNK (zeige MAPK8 Antikörper) signaling through dishevelled 1 (zeige DVL1 Antikörper) and 3, RhoA (zeige RHOA Antikörper) family members, and MEKK 1 (zeige MAP2K1 Antikörper) and 4 in mammalian cells

  8. Dvl1 (zeige DVL1 Antikörper), Dvl2 (zeige DVL2 Antikörper) and Dvl3 are functionally redundant in cardiac outflow tract, cochlea, and neural tube development.

Human Dishevelled, Dsh Homolog 3 (Drosophila) (DVL3) Interaktionspartner

  1. Dvl3 is overexpressed in human HCCs (zeige HCCS Antikörper). The NP-Dvl3 is the more stable and active form of the protein and enhances HCC (zeige FAM126A Antikörper) stemness.

  2. we found that Wnt3a (zeige WNT3A Antikörper) treatment rapidly induces hyperphosphorylation and stabilization of Dvl2 (zeige DVL2 Antikörper) and Dvl3. Our findings suggest a model of positive regulation of PKCzeta (zeige PRKCZ Antikörper)-mediated Dvl (zeige DVL2 Antikörper) signaling activity, to produce a strong and sustained response to Wnt3a (zeige WNT3A Antikörper) treatment by stabilizing Dvl (zeige DVL2 Antikörper) protein levels.

  3. Studied and identified candidate biomarkers of biochemical recurrence (BCR (zeige BCR Antikörper)) of prostate adenocarcinoma by integrating reverse-phase protein array (RPPA) and mRNA datafrom The Cancer Genome Atlas (TCGA). Found DVL3 was expressed in patients with a higher risk of BCR (zeige BCR Antikörper). DVL3 may be a novel and easily applicable recurrence predictor of localised prostate adenocarcinoma.

  4. two mutually exclusive functions of the DEP (zeige ZDHHC21 Antikörper) domain in Wnt (zeige WNT2 Antikörper) signal transduction - binding to Frizzled to recruit Dishevelled (zeige DVL2 Antikörper) to the receptor complex, is reported.

  5. Genetic changes between MLH1 (zeige MLH1 Antikörper) and MSH2 (zeige MSH2 Antikörper) were significantly positively correlated (p = 0.032). We also noted a positive correlation between genetic changes of MSH2 (zeige MSH2 Antikörper) and DVL3 genes (p = 0.034).

  6. Data show that dishevelled (zeige DVL2 Antikörper) proteins DVL1 (zeige DVL1 Antikörper), 2 and 3 were exclusively expressed in chronic lymphatic leukaemia (CLL) cells as compared to normal peripheral blood mononuclear cells (PBMCs).

  7. Kif26b (zeige KIF26B Antikörper), together with Dvl3/Daam1 (zeige DAAM1 Antikörper), initiates cell polarity through the control of planar cell polarity-signaling pathway-dependent activation in endothelial cells.

  8. DVL3 transcripts decreased in individuals with major depressive disorder

  9. we demonstrate that normally ALFY (zeige WDFY3 Antikörper) attenuates the canonical Wnt (zeige WNT2 Antikörper) signaling pathway via autophagy-dependent removal specifically of aggregates of DVL3 and not of Dvl1 (zeige DVL1 Antikörper) or Dvl2 (zeige DVL2 Antikörper).

  10. All variants in DVL3 result in a -1 frameshift, indicating that these highly specific alterations might be a common cause of dominant Robinow syndrome.

DVL3 Antigen-Profil

Protein Überblick

This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.

Genbezeichner und Symbole assoziert mit DVL3

  • dishevelled segment polarity protein 3 L homeolog (dvl3.L) Antikörper
  • dishevelled segment polarity protein 3 (dvl3) Antikörper
  • dishevelled segment polarity protein 3 (DVL3) Antikörper
  • dishevelled segment polarity protein 3 (Dvl3) Antikörper
  • dishevelled segment polarity protein 3a (dvl3a) Antikörper
  • dsh3 Antikörper
  • dvl3 Antikörper
  • wu:fb75f04 Antikörper
  • wu:fi22h02 Antikörper
  • wu:fp61b09 Antikörper

Bezeichner auf Proteinebene für DVL3

DSH homolog 3 , Dishevelled-3 , dishevelled, dsh homolog 3 , dishevelled3 , segment polarity protein dishevelled homolog DVL-3 , dishevelled, dsh homolog 3 (Drosophila) , dishevelled-3 , dishevelled 3 (homologous to Drosophila dsh) , dishevelled 3, dsh homolog , dishevelled 3 , dishevelled, dsh homolog 3a

444527 Xenopus laevis
100144702 Xenopus (Silurana) tropicalis
460882 Pan troglodytes
100220188 Taeniopygia guttata
100583216 Nomascus leucogenys
13544 Mus musculus
1857 Homo sapiens
539203 Bos taurus
303811 Rattus norvegicus
424949 Gallus gallus
478650 Canis lupus familiaris
100621038 Sus scrofa
80972 Danio rerio
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