anti-Developmental Pluripotency Associated 3 (DPPA3) Antikörper

DPPA3 encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. Zusätzlich bieten wir Ihnen DPPA3 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DPPA3 359787 Q6W0C5
DPPA3 73708 Q8QZY3
DPPA3 297576 Q6IMK0
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Top anti-DPPA3 Antikörper auf

Showing 10 out of 25 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-Stella/DPPA3 Polyclonal Antibody, Unconjugated (ABIN1713577) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Kaninchen Unkonjugiert IHC, IHC (p) 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 11 bis 14 Tage
Human Ziege Unkonjugiert ELISA   100 μg Anmelden zum Anzeigen 11 bis 14 Tage
Human Kaninchen Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert ELISA, WB Western Blot of Stella Antibody Western Blot of Stella antibody.   Lane A:  293 cell lysate at 1 µg/mL.   Lane B:  293 cell lysate at 2 µg/mL.   Load:  35 µg per lane. Secondary antibody:   Peroxidase rabbit secondary antibody at 1:10,000 for 45 min at RT. Block:  5% BLOTTO overnight at 4°C. Predicted/Observed size:  56.0 kDa, ~18 kDa for Stella. 100 μg Anmelden zum Anzeigen 1 bis 2 Tage
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Sample: Recombinant protein. DAB staining on IHC-P; Samples: Human Kidney Tissue 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Human Kaninchen Unkonjugiert WB   50 μg Anmelden zum Anzeigen 11 bis 14 Tage
Human Maus Unkonjugiert WB Western Blot analysis of DPPA3 expression in transfected 293T cell line by DPPA3 MaxPab polyclonal antibody.Lane 1: DPPA3 transfected lysate(17.49 KDa).Lane 2: Non-transfected lysate. 50 μg Anmelden zum Anzeigen 11 bis 12 Tage
Human Kaninchen Unkonjugiert WB   100 μg Anmelden zum Anzeigen 11 bis 16 Tage

Am meisten referenzierte anti-DPPA3 Antikörper

  1. Human Polyclonal DPPA3 Primary Antibody für IF (p), IHC (p) - ABIN1713577 : Wasielak, Więsak, Bogacka, Jalali, Bogacki: Zygote arrest 1, nucleoplasmin 2, and developmentally associated protein 3 mRNA profiles throughout porcine embryo development in vitro. in Theriogenology 2016 (PubMed)

Weitere Antikörper gegen DPPA3 Interaktionspartner

Cow (Bovine) Developmental Pluripotency Associated 3 (DPPA3) Interaktionspartner

  1. DPPA3 is a maternal factor important for correct epigenetic remodeling and normal embryonic development in cattle, indicating that the role of DPPA3 during early development is conserved between species.

Human Developmental Pluripotency Associated 3 (DPPA3) Interaktionspartner

  1. Super-enhancers at the Nanog locus differentially regulate neighboring pluripotency-associated genes, in particular, DPPA3.

  2. We conclude that heterogeneous population of the HEK293T cells might be easily shifted towards expression of the pluripotency markers by ectopic expression of the SON factors or by growth in serum depleted media.

  3. Data suggest enforced expression of Stella into normal cells induces not only global DNA demethylation but also neoplastic transformation and increases metastatic ability; these changes involve altered regulation of neoplastic gene expression.

  4. Considering that impaired DNA methylation profiles are associated with various developmental or disease phenomena, Stella may be a powerful tool with which to study the biological effects of global DNA hypomethylation

  5. a role for STELLA in facilitating germline and endodermal differentiation of human ES cells

  6. human adult tissue-specific transcripts originate via retrotransposition of the pluripotent cell-specific gene, Dppa3

  7. These results demonstrate that PGC7/Stella is indispensable for the maintenance of methylation involved in epigenetic reprogramming after fertilization.

  8. In mice, this gene may play a role in oogenesis and primordial germ cell development.

  9. In mice, a targeted mutation results in reduced female fertility and may function as a mammalian maternal effect gene.

  10. In mice, knockout experiments show this gene may be a maternal factor in cleavage stage embryogenesis.

Mouse (Murine) Developmental Pluripotency Associated 3 (DPPA3) Interaktionspartner

  1. Overexpression of Stella improves the efficiency of nuclear transfer reprogramming

  2. The absence of the DPPA3 cleavage products adversely affects pre-implantation development and female fertility.

  3. Through an in-depth bioinformatic analysis of potential interactors, PGC7 was linked to critical cellular processes including translation, RNA processing, cell cycle, and regulation of heterochromatin structure.

  4. PRDM1 and STELLA, while overlapping in putative primordial germ cells, also co-localize in several other tissues

  5. The authors show that loss of maternal Stella results in widespread transcriptional mis-regulation and a partial failure of maternal-to-zygotic transition.

  6. Data indicate STELLA's potential roles in building the fetal-placental connection.

  7. This study shows repression of the Dppa3 Locus in the absence of MAD2L2 embryonic stem cells.

  8. In-depth transcriptome analysis of this mESC state reveals Dppa3 as a direct downstream target of Tbx3.We show that Tbx3, a downstream target of Wnt signaling, fine tunes these divergent roles of Wnt signaling in mESCs

  9. Dppa3 has a critical role in generation of fully reprogrammed iPS cells and maintenance of Dlk1-Dio3 imprinting

  10. Stella protects maternal chromosomes from aberrant epigenetic modifications to ensure early embryogenesis.

  11. Chromocenter formation is impaired in Stella-null embryos.

  12. we propose that Dppa3 is involved in the Tet-mediated active demethylation process during reprogramming of primordial germ cells.

  13. PGC7 protects 5mC from Tet3-mediated conversion to 5hmC by binding to maternal chromatin containing dimethylated histone H3 lysine 9 (H3K9me2) in mice

  14. These Dppa3-MCM strains offer valuable opportunities to explore gene function in both loss-of-function and gain-of-function experiments at a variety of time points during germ cell development.

  15. DPPA3 is an essential factor for the production of functional oocytes through transcriptional repression and chromatin condensation.

  16. Data show that STELLA was found in both the nucleus and cytoplasm in a variety of cell types, both within and outside of the putative primordial germ cells (PGCs)trajectory.

  17. Data show that Stella is specifically expressed in preimplantation embryos and in the germline.

  18. embryos without Stella are compromised in preimplantation development and rarely reach the blastocyst stage

  19. Dppa3 is expressed in germ cells and is a marker of cell pluripotency.

  20. a marker of pluripotency: Stella-positive ESCs were like the inner cell mass, Stella-negative cells were like the epiblast cells

DPPA3 Antigen-Profil

Protein Überblick

This gene encodes a protein that in mice may function as a maternal factor during the preimplantation stage of development. In mice, this gene may play a role in transcriptional repression, cell division, and maintenance of cell pluripotentiality. In humans, related intronless loci are located on chromosomes 14 and X.

Genbezeichner und Symbole assoziert mit DPPA3

  • developmental pluripotency associated 3 (DPPA3) Antikörper
  • developmental pluripotency-associated 3 (Dppa3) Antikörper
  • 2410075G02Rik Antikörper
  • PCG7 Antikörper
  • PGC7 Antikörper
  • Stella Antikörper

Bezeichner auf Proteinebene für DPPA3

developmental pluripotency-associated protein 3 , stella , stella-related protein , developmental pluripotency associated 3 , compaction-associated protein 1 , primordial germ cell 7 , primordial germ cell protein 7

616433 Bos taurus
748273 Pan troglodytes
359787 Homo sapiens
73708 Mus musculus
297576 Rattus norvegicus
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