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DEK encodes a protein with one SAP domain. Zusätzlich bieten wir Ihnen DEK Kits (5) und DEK Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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Human Monoclonal DEK Primary Antibody für IF, WB - ABIN968269
Fu, Grosveld, Markovitz: DEK, an autoantigen involved in a chromosomal translocation in acute myelogenous leukemia, binds to the HIV-2 enhancer. in Proceedings of the National Academy of Sciences of the United States of America 1997
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Human Polyclonal DEK Primary Antibody für IHC (p), IP - ABIN253197
Datta, Adelson, Mogilevkin, Mordechai, Sidi, Trama: Oncoprotein DEK as a tissue and urinary biomarker for bladder cancer. in BMC cancer 2011
Human Polyclonal DEK Primary Antibody für IF (p), IHC (p) - ABIN729268
Yang, Wu, Geng, Liu, Yang, Chen, Ding, He, Wang, Xie: Roles of DEK in the endometrium of mice in early pregnancy. in Gene 2017
Cow (Bovine) Polyclonal DEK Primary Antibody für WB - ABIN2792543
Orlic, Spencer, Wang, Gallie: Expression analysis of 6p22 genomic gain in retinoblastoma. in Genes, chromosomes & cancer 2005
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Cow (Bovine) Polyclonal DEK Primary Antibody für WB - ABIN2792529
Chen, Gao, Hu, Pang, Cai, Li, Wu, Jiang: Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer. in Biochemical and biophysical research communications 2008
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High DEK expression is associated with breast cancer angiogenesis .
our study indicates that DEK expression is required for tumorigenesis and metastasis of hepatocellular carcinoma
High DEK expression is associated with melanoma progression.
DEK correlates with IL6 expression in HPV16+/p16+ oropharyngeal squamous cell carcinomas (OPSCC).
data support a scenario whereby overexpression of the human DEK oncogene reprograms keratinocyte metabolism to fulfill energy and macromolecule demands required to enable and sustain cancer cell growth
Decreased DEK expression in plasma cells suggests a potential role of this gene in plasma cell development and lack of detectable DEK protein by IHC could be used as a biomarker for normal and malignant plasma cells
Our data indicated DEK plays multiple roles to facilitate tumor growth and maintenance. It can be used as a potential target for astrocytic tumor diagnosis and gene therapy.
High DEK expression is associated with pancreatic ductal adenocarcinoma.
AP-2a is an important transcription factor of DEK expression, which is correlated with the methylation level of the DEK core promoter in hepatocellular carcinoma .
miR (zeige MLXIP Antikörper)-592 targets DEK transcript and suppresses hepatocellular carcinoma cell growth
Data suggests that DEK participates in the process of embryo implantation and might play a role in influencing stromal cell decidualization through mediating cell proliferation, apoptosis and DNA damage.
DEK expression during normal hematopoiesis did reveal a relationship with specific cell types implicating a distinct function during myeloid differentiation
Studies demonstrate that DEK overexpression, due in part to Ron (zeige MST1R Antikörper) receptor activation, drives breast cancer progression through the induction of Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) signaling.
Results highlight a novel function of DEK as a guardian of chromatin by restricting widespread histone access, and in particular by modulating differential H3.3 loading in specific chromatin areas.
data demonstrate that DEK stimulates HNSCC cellular growth and identify DeltaNp63 as a novel DEK effector
DEK has potent effects on HSCs, HPCs, and hematopoiesis, information of biological and potential clinical interest.
The hallmark of translocation in acutte myeloid leukemiaa is the expression of the DEK/CAN fusion protein.
DEK is a neuroblastoma (zeige ARHGEF16 Antikörper) tumor antigen.
Our conclusion is that DEK could serve as an architectural protein at the promoter or enhancer sites of a subfraction of human genes.
Overexpression of the cellular DEK protein promotes epithelial transformation in vitro and in vivo.
This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.
DEK oncogene (DNA binding)
, protein DEK
, DEK oncogene