DEK Antikörper (Middle Region)

Produktnummer ABIN2792529

Produktdetails anti-DEK Antikörper

Target: DEK (DEK Oncogene (DEK))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DEK Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: ELKETIKKLL ASANLEEVTM KQICKKVYEN YPTYDLTERK DFIKTTVKEL

Kreuzreaktivität: Rind (Kuh), Huhn, Human, Maus, Ratte (Rattus)

Homologie: Cow: 85%, Guinea Pig: 85%, Horse: 85%, Human: 100%, Mouse: 85%, Pig: 78%, Rabbit: 85%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against DEK. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human DEK

Anwendungsinformationen

Applikationshinweise: WB Suggested Anti-DEK Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: MCF7 cell lysate.
Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 375 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-DEK Antikörper (ABIN2792529)

Chen, Gao, Hu, Pang, Cai, Li, Wu, Jiang: "Galactose-poly(ethylene glycol)-polyethylenimine for improved lung gene transfer." in: Biochemical and biophysical research communications, Vol. 375, Issue 3, pp. 378-83, (2008) (PubMed).

Details zu DEK

Target: DEK (DEK Oncogene (DEK))

Andere Bezeichnung: DEK (DEK Produkte)

Synonyme: D6S231E antikoerper, DEK antikoerper, 1810019E15Rik antikoerper, D13H6S231E antikoerper, DEK proto-oncogene antikoerper, DEK proto-oncogene L homeolog antikoerper, DEK oncogene (DNA binding) antikoerper, DEK oncogene antikoerper, DEK antikoerper, Dek antikoerper, dek.L antikoerper, LOC398543 antikoerper

Hintergrund: DEK is a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene.This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene and the presence of antibodies against this protein are all associated with various diseases. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: D6S231E
Protein Interaction Partner: CUL3, SPOP, UBC, EED, IRF2BP2, GANAB, PTPN12, CSNK2A2, CSNK2A1, TP53BP1, ESR1, VTN, S100A9, RPL37A, DHX15, FTSJ3, WIBG, TMED9, EXOSC2, UTP14A, THRAP3, CAND1, COPS5, CDK2, YWHAZ, Cebpb, ELAVL1, SUMO1, SUMO2, RAD21, HDGF, KAT2B, EP300, CREBBP, HIST1H4A, HDA
Protein Size: 375

Molekulargewicht: 43 kDa

Gen-ID: 7913

NCBI Accession: NM_003472, NP_003463

UniProt: P35659