anti-Cytokine Receptor-Like Factor 2 (CRLF2) Antikörper

The protein encoded by CRLF2 is a receptor for thymic stromal lymphopoietin (TSLP). Zusätzlich bieten wir Ihnen CRLF2 Proteine (17) und CRLF2 Kits (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CRLF2 64109 Q9HC73
CRLF2 57914 Q8CII9
CRLF2 171499  
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Top anti-CRLF2 Antikörper auf antikoerper-online.de

Showing 10 out of 132 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-CRLF2 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  721_B cell lysate WB Suggested Anti-CRLF2  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control:.21_B cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Maus Unkonjugiert CyTOF, FACS, WB Detection of TSLP R in Human PBMC Monocytes by Flow Cytometry. Human PBMC monocytes were stained with Human TSLP R Monoclonal Antibody. 500 μg Anmelden zum Anzeigen 8 bis 9 Tage
$397.76
Details
Maus Ziege Unkonjugiert CyTOF, FACS, Neut, WB Detection of TSLP R in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TSLP R Antigen Affinity-purified Polyclonal Antibody. Cell Proliferation Induced by TSLP and Neutralization by Mouse TSLP R Antibody. Recombinant Mouse TSLP. The ND50 is typically 0.2-0.6 ug/mL. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$416.97
Details
Maus Ziege PE FACS Detection of TSLP R in Mouse Splenocytes by Flow Cytometry. Mouse splenocytes were stained with Goat Anti-Mouse TSLP R PE-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Anmelden zum Anzeigen 8 bis 9 Tage
$352.56
Details
Human Maus Unkonjugiert ELISA, WB CRLF2 monoclonal antibody (M03), clone 4A11 Western Blot analysis of CRLF2 expression in Hela NE. Detection limit for recombinant GST tagged CRLF2 is approximately 3 ng/mL as a capture antibody. 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$527.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$434.50
Details
Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB Human Kidney (formalin-fixed, paraffin-embedded) stained with CRLF2 antibody ABIN461904 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. Human Liver (formalin-fixed, paraffin-embedded) stained with CRLF2 antibody ABIN461904 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details
Human Maus Unkonjugiert FACS, Neut   100 μg Anmelden zum Anzeigen 15 bis 18 Tage
$222.56
Details
Maus Kaninchen Unkonjugiert EIA, WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$474.10
Details

Am meisten referenzierte anti-CRLF2 Antikörper

  1. Human Monoclonal CRLF2 Primary Antibody für FACS, Neut - ABIN2689945 : Arima, Watanabe, Hanabuchi, Chang, Sun, Liu: Distinct signal codes generate dendritic cell functional plasticity. in Science signaling 2010 (PubMed)
    Show all 9 Pubmed References

  2. Human Monoclonal CRLF2 Primary Antibody für CyTOF, FACS - ABIN4899885 : Shan, Redhu, Saleh, Halayko, Chakir, Gounni: Thymic stromal lymphopoietin receptor-mediated IL-6 and CC/CXC chemokines expression in human airway smooth muscle cells: role of MAPKs (ERK1/2, p38, and JNK) and STAT3 pathways. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 4 Pubmed References

  3. Mouse (Murine) Polyclonal CRLF2 Primary Antibody für CyTOF, FACS - ABIN4899486 : Osborn, Ryan, Kirchhof, Panoskaltsis-Mortari, Mortari, Tudor: Overexpression of murine TSLP impairs lymphopoiesis and myelopoiesis. in Blood 2004 (PubMed)
    Show all 4 Pubmed References

  4. Mouse (Murine) Polyclonal CRLF2 Primary Antibody für FACS - ABIN4896188 : Oh, Oh, Yu, Myers, Leonard, Liu, Zhu, Zheng: IL-13 induces skin fibrosis in atopic dermatitis by thymic stromal lymphopoietin. in Journal of immunology (Baltimore, Md. : 1950) 2011 (PubMed)
    Show all 4 Pubmed References

  5. Mouse (Murine) Polyclonal CRLF2 Primary Antibody für WB - ABIN541606 : Levin, Koelling, Friend, Isaksen, Ziegler, Perlmutter, Farr: Thymic stromal lymphopoietin: a cytokine that promotes the development of IgM+ B cells in vitro and signals via a novel mechanism. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Show all 3 Pubmed References

  6. Mouse (Murine) Polyclonal CRLF2 Primary Antibody für FACS - ABIN4896186 : Bao, Zhang, Yao, Lu, Tong, Yan, Tu, Yang, Zhou: Deguelin Attenuates Allergic Airway Inflammation via Inhibition of NF-κb Pathway in Mice. in International journal of biological sciences 2018 (PubMed)

  7. Human Polyclonal CRLF2 Primary Antibody für IHC (p), WB - ABIN2476989 : AuBuchon, Brightman: Use of indium-111 as a red cell label. in Transfusion 1989 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal CRLF2 Primary Antibody für ELISA, ICC - ABIN4363174 : Morshed, Yousefi, Stöckle, Simon, Simon: Thymic stromal lymphopoietin stimulates the formation of eosinophil extracellular traps. in Allergy 2012 (PubMed)

  9. Human Polyclonal CRLF2 Primary Antibody für IHC, ELISA - ABIN1003386 : Sims, Williams, Morrissey, Garka, Foxworthe, Price, Friend, Farr, Bedell, Jenkins, Copeland, Grabstein, Paxton: Molecular cloning and biological characterization of a novel murine lymphoid growth factor. in The Journal of experimental medicine 2000 (PubMed)
    Show all 4 Pubmed References

  10. Mouse (Murine) Polyclonal CRLF2 Primary Antibody für ELISA, WB - ABIN1003387 : Park, Martin, Garka, Gliniak, Di Santo, Muller, Largaespada, Copeland, Jenkins, Farr, Ziegler, Morrissey, Paxton, Sims: Cloning of the murine thymic stromal lymphopoietin (TSLP) receptor: Formation of a functional heteromeric complex requires interleukin 7 receptor. in The Journal of experimental medicine 2000 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen CRLF2 Interaktionspartner

Human Cytokine Receptor-Like Factor 2 (CRLF2) Interaktionspartner

  1. Family-based whole genome analysis of a family with hereditary pulmonary alveolar proteinosis revealed a homozygous deletion that disrupts CSF2RA, CRLF2, and IL3RA gene in the pseudoautosomal region of the X chromosome in the affected child and one of asymptomatic siblings.

  2. TSLP expression on the basophil membrane of patients with severe asthma was not significantly different from healthy controls.

  3. high CRLF2 expression works with the IKZF1 deletion to drive oncogenesis of acute lymphoblastic leukemia

  4. this study shows that CRLF2 over-expression is a poor prognostic marker in children with high risk T-cell acute lymphoblastic leukemia

  5. data suggest that this high frequency of genetic aberrations in the context of a high CRLF2 expression could contribute to the high risk of relapse in P2RY8/CRLF2- and IGH/CRLF2-positive acute lymphoblastic leukemia.

  6. CRLF2 overexpression is associated with childhood B-cell acute lymphoblastic leukemia.

  7. CRLF2 gene rearrangement is associated with acute lymphoblastic leukemia.

  8. TSLPR levels were found to be significantly higher in asthmatic than in nonasthmatic children. TSLPR expression in non-allergic asthmatic and allergic asthmatic groups was found to be significantly higher than in non-allergic nonasthmatic group

  9. In adult B-cell acute lymphoblastic leukemia without recurrent fusion genes , high CRLF2 expression is associated with distinct clinico-biological features and an unfavourable prognosis

  10. CD4+ T cells from atopic dermatitis patients directly interacted with TSLP to produce a higher amount of IL-4 than those from normal subjects, and this action was attenuated with anti-TSLPR antibody

  11. The levels of mRNA for TSLP and TSLPR were significantly elevated in parotid gland tissues from the KD group as compared to the control group.

  12. Differences exist in the genetic profiles of Down syndrome-associated acute lymphoblastic leukemia patients in Japan and in Western countries, and that P2RY8-CRLF2 and EBF1 deletions may cooperate in leukemogenesis in a subset of Japanese DS-ALL patients.

  13. CRLF2 overexpression (OE) was detected in 30 (18%) of 167 patients, the P2RY8-CRLF2 fusion was identified in only 3 (1.8%) of 167 patients, all of which demonstrated CRLF2 OE.

  14. we report noncysteine in-frame mutations in IL7R and CRLF2 located in a region of the transmembrane domain closer to the cytosolic domain in acute lymphoblastic leukemias

  15. The TSLPR in blood plateltes promotes platelet activation via activating the PI3K/AKT pathway.

  16. both IKZF1 deletions and IGH@-CRLF2 are associated with an increased risk of treatment failure in adult acute lymphoblastic leukemia

  17. Data indicate that CD66c is frequently expressed in CRLF2-positive as well as hypodiploid cases.

  18. Higher cumulative incidence of relapse was found for BCR-ABL1-like and IKZF1-deleted, but not CRLF2-high, cases relative to remaining BCP-ALL cases.

  19. IKZF1 deletions and CRLF2-high expression predicted poor outcomes in patients with HR-ALL but not in patients with SR-ALL in our Japanese cohort

  20. Results show no clinical or laboratory difference between those with high and low crlf2 expression

Mouse (Murine) Cytokine Receptor-Like Factor 2 (CRLF2) Interaktionspartner

  1. these results suggest that TSLP-TSLPR signaling is pivotal in the induction of nasal respiratory immunity against pathogenic pneumococcal infection

  2. A novel mouse xenograft model to study the role of TSLP-induced CRLF2 signals in normal and malignant human B lymphopoiesis has been developed.

  3. High-cholesterol diet increased TSLPR expression and atherosclerosis. High-dose ticagrelor moderated this trend. It modulated platelet activity and atherosclerosis mediated by TSLPR, potentially through the PI3K/Akt signal pathway.

  4. Activating thymic stromal lymphopoietin promotes atherosclerosis by inducing Th17/Treg imbalance through TSLPR signaling in a mouse model.

  5. Suggest that Treg defects in ApoE(-/-) mice might partially be attributed to the disruption of TSLP-TSLPR-LAP signaling in epithelial cells and dendritic cells.

  6. The structure of the mouse TSLP-mediated signaling complex reveals how TSLP establishes extensive interfaces with its cognate receptor (TSLPR).

  7. TSLPR helps to create a permissive microenvironment for the development and pulmonary metastasis of mammary carcinoma in a mouse model using implanted 4T1 tumour cells.

  8. A previously unrecognized role was found for TSLP/TSLPR signaling in type 2 immunity as an important enhancer for the development of alternately activated macrophages as well as for chemokine production.

  9. mice deficient in TSLP receptors on LCs abrogated the induction of OVA-specific IgE levels upon epicutaneous OVA sensitization.

  10. Increased susceptibility to autoimmune gastritis in thymic stromal lymphopoietin receptor-deficient mice.

  11. Presence of functional TSLP-specific receptor chain is required for the development of T helper cell type (Th)2 contact hypersensitivity to the hapten fluorescein isothiocyanate (FITC).

  12. Induced homodimerization of receptor chimeras containing the transmembrane and cytoplasmic domains of both human and mouse TSLP receptors is not sufficient for driving cell proliferation.

  13. expression pattern in antigen presenting cells

  14. B-cell development, including the IgM+ compartment, was unaffected by loss of the TSLPR pathway.

  15. molecular cloning of Tslpr in insect cells or COS cells resulted in expression of mTSLPR with an extracellular C-terminal end, a surprising result since the N-terminal region contains a signal sequence and two potential glycosylation sites

  16. local application of anti-TSLPR prevented Th2-mediated airway inflammation, at least partly, by regulating DCs function, which might be exploited to develop novel treatments for asthma.

CRLF2 Antigen-Profil

Protein Überblick

The protein encoded by this gene is a receptor for thymic stromal lymphopoietin (TSLP). Together with the interleukin 7 receptor (IL7R), the encoded protein and TSLP activate STAT3, STAT5, and JAK2 pathways, which control processes such as cell proliferation and development of the hematopoietic system. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit CRLF2

  • cytokine receptor like factor 2 (CRLF2) Antikörper
  • cytokine receptor-like factor 2 (Crlf2) Antikörper
  • Crl2 Antikörper
  • CRLF2 Antikörper
  • CRLF2Y Antikörper
  • CRLM2 Antikörper
  • Ly114 Antikörper
  • Tpte2 Antikörper
  • Tslpr Antikörper

Bezeichner auf Proteinebene für CRLF2

cytokine receptor-like factor 2 , IL-XR , P2RY8/CRLF2 fusion , TSLP receptor , cytokine receptor CRL2 precusor , cytokine receptor-like 2 , thymic stromal lymphopoietin protein receptor , thymic stromal lymphopoietin receptor , thymic stromal-derived lymphopoietin receptor , CRLM-2 , cytokine receptor-like molecule 2 , delta 1 , lymphocyte antigen 114 , thymic stromal-derived lymphopoietin, receptor , transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 , type I cytokine receptor delta 1

GENE ID SPEZIES
491709 Canis lupus familiaris
529792 Bos taurus
749758 Pan troglodytes
100582238 Nomascus leucogenys
64109 Homo sapiens
57914 Mus musculus
171499 Rattus norvegicus
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