Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1) ELISA Kits

CYP27A1 encodes a member of the cytochrome P450 superfamily of enzymes. Zusätzlich bieten wir Ihnen CYP27A1 Antikörper (67) und CYP27A1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
CYP27A1 1593 Q02318
CYP27A1 301517 P17178
CYP27A1 104086 Q9DBG1
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Top CYP27A1 ELISA Kits auf antikoerper-online.de

Showing 4 out of 12 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 0.055 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
$736.84
Details
Maus < 0.07 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
Details
Ratte < 0.07 ng/mL 0.156 ng/mL - 10 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$795.96
Details
Human
  96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$380.00
Details

Am meisten referenzierte CYP27A1 ELISA Kits

  1. Human CYP27A1 ELISA Kit für Sandwich ELISA - ABIN419215 : Zhao, Li, Wang, Habib, Wei, Sun, Strobel, Jia: Vitamin D serum level is associated with Child-Pugh score and metabolic enzyme imbalances, but not viral load in chronic hepatitis B patients. in Medicine 2016 (PubMed)

Weitere ELISA Kits für CYP27A1 Interaktionspartner

Human Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1) Interaktionspartner

  1. Vitamin D supplementation can decrease circulating 27HC of breast cancer patients, likely by CYP27A1 inhibition. This suggests a new and additional modality by which vitamin D can inhibit ER+ breast cancer growth, though a larger study is needed for verification.

  2. Whole-exome sequencing assuming recessive inheritance determined his genetic diagnosis to be cerebrotendinous xanthomatosis caused by homozygous mutations (c.410G>A or p.Arg137Gln) in the cytochrome P450 (zeige CYP ELISA Kits) subfamily 27 A1 (CYP27A1) gene

  3. Three novel mutations in CYP27A1 were found in cerebrotendinous xanthomatosis patients in Chinese families

  4. Increased maternal and fetal cholesterol efflux capacity and placental CYP27A1 expression in preeclampsia

  5. Molecular study identified a novel homozygous frameshift mutation in CYP27A1 gene in cerebrotendinous xanthomatosis without cataract

  6. Cerebrotendinous xanthomatosis .. is caused by mutations in the CYP27A1 gene that result in decreased production of chenodeoxycholic acid (CDCA) and elevated levels of cholestanol and bile alcohols. Sequencing of CYP27A1 showed a paternally inherited splice mutation, c.446 + 1G>T, and a maternally inherited nonsense mutation, c.808C>T, predicting p.(Arg270*).

  7. we demonstrated the rare missense variant of CYP27A1 is associated with atopic dermatitis with elevated levels of total serum IgE.

  8. The 32 kb deleted region harbors the CYP2A7 gene and was enriched with enhancer, repressor and insulator sites. The wildtype allele was lost in the polyps of the proband

  9. CYP27A1 is a critical cellular cholesterol sensor in prostate cells and that dysregulation of the CYP27A1/27-hydroxycholesterol (27HC) axis contributes significantly to prostate cancer pathogenesis.

  10. CYP27A1 catalyzes hydroxylation of beta-sitosterol and ergosterol

Mouse (Murine) Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1) Interaktionspartner

  1. In het mice, RIF had no effect on plasma lipids composition, CYP27A1 activity, and atherosclerotic plaque development, despite a reduction in cholesterol absorption. In conclusion, the antiatherogenic effect of Cyp3a11 induction by RIF was also dependent on Cyp27a1 expression.

  2. CYP46A1 (zeige CYP46A1 ELISA Kits) is involved in cholestanol removal from the brain and that several factors contribute to the preferential increase in cholestanol in the cerebellum arising from CYP27A1 deficiency.

  3. The cholesterol diet reduced the levels of the "memory protein" Arc (Activity Regulated Cytoskeleton associated protein (zeige Arc ELISA Kits)) in the hippocampus of the wildtype mice but not in the hippocampus of the Cyp27-/- mice.

  4. overexpression of Cyp27a1 in KCs reduces hepatic inflammation independently of 27HC levels in plasma and liver, further pointing towards KCs as specific target for improving the therapy of NASH.

  5. Data indicate that inhibition of CYP27A1 activity or knockdown and deletion of the Cyp27a1 gene induced adipocyte differentiation.

  6. The expression of CYP27A1 modulates the concentrations of active glucocorticoids in both humans and mice and in vitro.

  7. Loss of CYP27A1 led to dysregulation of retinal cholesterol homeostasis, including unexpected upregulation of retinal cholesterol biosynthesis. Cyp27a1-/- mice developed retinal lesions with cholesterol deposition beneath the retinal pigment epithelium.

  8. CYP27(-/-) mice exhibited enhanced CCl(4 (zeige CCL4 ELISA Kits))-induce liver injury, and defective liver regeneration and prolonged steatosis after 70% partial hepatectomy.

  9. Results are consistent with a concentration-dependent flux of 7alpha-hydroxy-4-cholesten-3-one across the blood-brain barrier in cyp27a1(-/-) mice and subsequent formation of cholestanol.

  10. In CYP27A1 ko mice, urinary progesterone concentrations were decreased, 20alpha-DH-progesterone increased, and the progesterone-to-20alpha-DH-progesterone ratio decreased threefold

Cow (Bovine) Cytochrome P450, Family 27, Subfamily A, Polypeptide 1 (CYP27A1) Interaktionspartner

  1. isoLG adduction impairs enzyme activity, and support our hypothesis that isoLG modification in the retina is detrimental to CYP27A1 enzyme activity, potentially disrupting cholesterol homeostasis.

  2. Features of the retinal environment which affect the activities and product profile of cholesterol-metabolizing cytochromes P450 (zeige POR ELISA Kits) CYP27A1 and CYP11A1 (zeige CYP11A1 ELISA Kits).

  3. Sterol 27-hydroxylase cytochrome P450 27A1 (CYP27A1) is involved in elimination of 7-ketocholesterol from the retinal pigment epithelium.

CYP27A1 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease.

Genbezeichner und Symbole assoziert mit CYP27A1

  • cytochrome P450 family 27 subfamily A member 1 (CYP27A1) Antikörper
  • cytochrome P450, family 27, subfamily a, polypeptide 1 (Cyp27a1) Antikörper
  • cytochrome P450, family 27, subfamily A, polypeptide 1 (CYP27A1) Antikörper
  • sterol 26-hydroxylase, mitochondrial (CYP27A1) Antikörper
  • cytochrome P450, family 27, subfamily A, polypeptide 1 (cyp27a1) Antikörper
  • 1300013A03Rik Antikörper
  • CP27 Antikörper
  • CTX Antikörper
  • Cyp27 Antikörper
  • P450C27 Antikörper

Bezeichner auf Proteinebene für CYP27A1

5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 26-hydroxylase , 5-beta-cholestane-3-alpha, 7-alpha, 12-alpha-triol 27-hydroxylase , 5-beta-cholestane-3-alpha,7-alpha,12-alpha-triol 27-hydroxylase , cholestanetriol 26-monooxygenase , cytochrome P-450C27/25 , cytochrome P450 27 , cytochrome P450, subfamily XXVIIA (steroid 27-hydroxylase, cerebrotendinous xanthomatosis), polypeptide 1 , sterol 26-hydroxylase, mitochondrial , sterol 27-hydroxylase , vitamin D(3) 25-hydroxylase , cytochrome P-450c27/25 , cholesterol 27 hydroxylase , cytochrome P450, 27 , cytochrome P450, 27a1

GENE ID SPEZIES
1593 Homo sapiens
301517 Rattus norvegicus
104086 Mus musculus
610489 Canis lupus familiaris
100126282 Sus scrofa
511960 Bos taurus
100348736 Oryctolagus cuniculus
100381137 Xenopus laevis
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