anti-Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Antikörper

CYP2E1 encodes a member of the cytochrome P450 superfamily of enzymes. Zusätzlich bieten wir Ihnen Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Kits (49) und Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Proteine (24) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CYP2E1 1571 P05181
CYP2E1 13106 Q05421
CYP2E1 25086 P05182
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Top anti-Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Antikörper auf antikoerper-online.de

Showing 10 out of 180 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IF, IHC, ELISA Immunohistochemistry analysis of paraffin-embedded human brain tissue, using Cytochrome P450 2E1 Antibody. The picture on the right is treated with the synthesized peptide. Immunofluorescence analysis of HepG2 cells, using Cytochrome P450 2E1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- CYP2E1 antibody, IHC(P) IHC(P): Rat Liver Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
$368.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB   100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of CYP2E1 Antibody (C-term) (ABIN652585) in K562 cell line lysates (35 µg/lane). CYP2E1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with CYP2E1 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details
Human Kaninchen Unkonjugiert WB 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$240.00
Details
Maus Kaninchen Unkonjugiert IHC (p), WB Anti-Cytochrome P450 2E1 antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: Mouse Liver Tissue Lysate Anti-Cytochrome P450 2E1 antibody, IHC(P) IHC(P): Rat Liver Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Human Ziege Unkonjugiert EIA, IHC (p), WB AP22383PU-N CYP2E1 antibody staining of paraffin embedded Human Liver at 3.8 µg/ml. Steamed antigen retrieval with citrate buffer pH 6, AP-staining. AP22383PU-N CYP2E1 antibody staining of Human Liver lysate at 0.05µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: Cytochrome P450 2E1 Antibody [NBP1-85367] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp.Lane 4: Human plasma (IgG/HSA depleted) Western Blot: Cytochrome P450 2E1 Antibody [NBP1-85367] - Lane 1: Mouse liver tissue lysate.Lane 2: Rat liver tissue lysate 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
Details

CYP2E1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Antikörper

  1. Human Polyclonal CYP2E1 Primary Antibody für WB - ABIN3043000 : Fan, Jiang, Wang, Tan, Zeng, Wang, Chen, Qu, Gonzalez, Huang, Bi: Wuzhi tablet (Schisandra Sphenanthera extract) protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of NRF2-ARE and p53/p21 pathways. in Drug metabolism and disposition: the biological fate of chemicals 2014 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal CYP2E1 Primary Antibody für IHC (p), WB - ABIN4886556 : Jiang, Fan, Wang, Chen, Zeng, Tan, Gonzalez, Huang, Bi: Schisandrol B protects against acetaminophen-induced hepatotoxicity by inhibition of CYP-mediated bioactivation and regulation of liver regeneration. in Toxicological sciences : an official journal of the Society of Toxicology 2014 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal CYP2E1 Primary Antibody für IHC (p), WB - ABIN3043821 : Chen, Sun, Han, Peng, Li, Liu, Lv, Liu, Zhou, Sun: Protective effect of tea polyphenols against paracetamol-induced hepatotoxicity in mice is significantly correlated with cytochrome P450 suppression. in World journal of gastroenterology 2009 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal CYP2E1 Primary Antibody für WB - ABIN514837 : De Bock, Colin, Boussery, Van Bocxlaer: Quantification of cytochrome 2E1 in human liver microsomes using a validated indirect ELISA. in Journal of pharmaceutical and biomedical analysis 2013 (PubMed)

  5. Human Polyclonal CYP2E1 Primary Antibody für ELISA, IHC - ABIN4302103 : Niu, Yuan, Leng, Pang, Gu, Chen: CYP2E1 Rsa I/Pst I polymorphism and esophageal cancer risk: a meta-analysis based on 1,088 cases and 2,238 controls. in Medical oncology (Northwood, London, England) 2011 (PubMed)

  6. Human Polyclonal CYP2E1 Primary Antibody für IHC, IHC (p) - ABIN4302106 : Hou, Bukong, Kodys, Szabo: Alcohol facilitates HCV RNA replication via up-regulation of miR-122 expression and inhibition of cyclin G1 in human hepatoma cells. in Alcoholism, clinical and experimental research 2013 (PubMed)

  7. Human Polyclonal CYP2E1 Primary Antibody für IHC, IHC (p) - ABIN4302104 : Fagerberg, Hallström, Oksvold, Kampf, Djureinovic, Odeberg, Habuka, Tahmasebpoor, Danielsson, Edlund, Asplund, Sjöstedt, Lundberg, Szigyarto, Skogs, Takanen, Berling, Tegel, Mulder, Nilsson, Schwenk et al.: Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics. ... in Molecular & cellular proteomics : MCP 2014 (PubMed)

Weitere Antikörper gegen Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Interaktionspartner

Rabbit Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Interaktionspartner

  1. The localization of CYP1A2 (zeige CYP1A2 Antikörper), CYP2B4 and CYP2E1 within the ER was determined by partial membrane solubilization with Brij 98

Guinea Pig Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Interaktionspartner

  1. Cytochrome P450 2E1 takes part in the pathogenesis of experimental metabolic syndrome in guinea pigs.

Human Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Interaktionspartner

  1. Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction.

  2. Polymorphisms in the promoter region of the CYP2E1 gene were associated with DNA damage in alcoholics.

  3. We identified an exposure-associated differentially methylated region (DMR (zeige WDR20 Antikörper)) spanning nine sequential CpG sites in the promoter-regulatory region of the cytochrome P450 2E1 gene (CYP2E1) on chromosome 10 (corrected P=2.98 x 10(-5)). Elevated DNA methylation (zeige HELLS Antikörper) across this region was also associated with deprivation-related clinical markers of impaired social cognition.

  4. A significant increase in the risk of non-small cell lung cancer was observed for the following combinations: TP53 (zeige TP53 Antikörper) codon72 variant with GSTM1 (zeige GSTM1 Antikörper) null (OR 2.22, 95 % CI 1.23-4.04; p=0.009), GSTT1 (zeige GSTT1 Antikörper) null (OR 2.98, 95 % CI 1.49-5.94; p=0.002), and GSTP1 (zeige GSTP1 Antikörper) (Ala114Val) variant genotypes (OR 3.38, 95 % CI 1.54-7.41; p=0.002).

  5. Studied the possible relationship between cytochrome P450 (zeige CYP Antikörper), family 2, subfamily E and polypeptide 1 (zeige CYP Antikörper) (CYP2E1) polymorphisms with Kawasaki disease (KD). Found the KD patients with a CYP2E1 CC genotype of rs915906 demonstrated a greater proportion of coronary artery lesions (CALs (zeige CA8 Antikörper)) formation.

  6. The results suggest that changes in coumarin pharmacokinetics and CYP2E1 subcellular distribution contribute to resistance to coumarin-induced hepatic necrosis, while cytotoxicity of metabolic conjugates shown in vitro may contribute to bile duct damage upon repeated coumarin administration.

  7. Data suggest a homeostatic, gene dosage-insensitive regulation of CYP2E1 expression by unknown gene dosage compensation mechanisms.

  8. Data suggest that microRNA-214-3p (but not microRNA-942-5p) suppresses expression of CYP2E1 in hepatocytes; microRNA-214-3p interacts with two binding sites located in protein coding region of CYP2E1 mRNA. (CYP2E1 = cytochrome P450 (zeige CYP Antikörper) family 2 subfamily E member 1)

  9. The synergistic effect of VK2 and EtOH was also observed in QGY-7703 cells, which also express CYP2E1. However, in HepG2 cells, which do not express CYP2E1, the synergistic effect of VK2 and EtOH was not observed

  10. The results suggest that there is no evidence for a major role of CYP2E1 polymorphism in liver carcinogenesis, but do not rule out the possibility in certain cases. [meta-analysis]

Mouse (Murine) Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Interaktionspartner

  1. Methodology to assay CYP2E1 mixed function oxidase catalytic activity and its induction/

  2. we show that TRPV4 (zeige TRPV4 Antikörper) is activated both by damage associated molecular pattern HMGB1 (zeige HMGB1 Antikörper) and collagen in diseased Kupffer cells that in turn activate the endothelial NOS (NOS3 (zeige NOS3 Antikörper)) to release nitric oxide (NO). The diffusible NO acts in a paracrine fashion in neighboring hepatocytes to deactivate the redox toxicity induced by CYP2E1

  3. Data, including data from studies in knockout mice, suggest that the oxidative metabolism of 1,2-dichloropropane, a carcinogenic solvent/insecticide, is exclusively catalyzed by Cyp2e1; this biotransformation step is indispensable for manifestation of hepatotoxic effect of the solvent.

  4. Taken together, these results suggested that 1,2-dichloroethane (1,2-DCE (zeige DHCR24 Antikörper)) could enhance CYP2E1 protein expression and enzymatic activity, which could cause oxidative damage in liver, serving as an important mechanism underlying 1,2-DCE (zeige DHCR24 Antikörper)-induced liver damage

  5. CYP2E1 is important in causing aging-dependent hepatic steatosis, apoptosis and fibrosis possibly through increasing nitroxidative stress.

  6. Our results support a significant role for CYP2E1 as a novel 4-Aminobiphenyl N-oxidizing enzyme in adult mice

  7. Schisandrol B protects against APAP-induced liver injury, potentially through inhibition of CYP2E1/3A11-mediated APAP bioactivation and regulation of the p53 (zeige TP53 Antikörper), p21 (zeige D4S234E Antikörper), CCND1 (zeige CCND1 Antikörper), PCNA (zeige PCNA Antikörper), and BCL-2 (zeige BCL2 Antikörper) to promote liver regeneration.

  8. Studied hepatic stellate cell cytoglobin (zeige CYGB Antikörper) involvement in acetaminophen induced hepatotoxicity through the regulation of CYP2E1.

  9. Data suggest that expression of Cyp2e1 in adipose tissue can be regulated by dietary factors; here, expression of Cyp2e1 in white adipose tissue is down-regulated in obesity caused by high-fat diet.

  10. The Cyp2e1-null mice displayed a susceptibility to lung toxicity of styrene similar to that of the wild-type animals; however, Cyp2f2-null mice were resistant to styrene-induced pulmonary toxicity.

Pig (Porcine) Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Interaktionspartner

  1. A highly significant association was found between variation in skatole levels and SNPs within the CYP2E1 gene on chromosome 14.

  2. The relationship between a single nucleotide polymorphism of CYP2E1 and boar taint in pork from Belgian swine is reported.

Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Antigen-Profil

Protein Überblick

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

Genbezeichner und Symbole assoziert mit CYP2E1

  • cytochrome P450, family 2, subfamily E, polypeptide 1 (CYP2E1) Antikörper
  • cytochrome P450 2E1 (CYP2E1) Antikörper
  • cytochrome P450 2E1 (PTRG_07411) Antikörper
  • cytochrome P450 2E1 (LOC100342572) Antikörper
  • cytochrome P450 2E1 (LOC100727914) Antikörper
  • cytochrome P450 2E1-like (LOC101843716) Antikörper
  • cytochrome P450 family 2 subfamily E member 1 (CYP2E1) Antikörper
  • cytochrome P450, family 2, subfamily e, polypeptide 1 (Cyp2e1) Antikörper
  • CPE1 Antikörper
  • Cyp2e Antikörper
  • CYP2E1 Antikörper
  • CYPIIE1 Antikörper
  • P450-J Antikörper
  • P450C2E Antikörper

Bezeichner auf Proteinebene für CYP2E1

cytochrome P450 2E1 , 4-nitrophenol 2-hydroxylase , Cytochrome P450 2E1 , Cytochrome P450 LM3A , Cytochrome P450 isozyme 3A , Cytochrome P450-ALC , Cytochrome P450-J , cytochrome P-450j , CYPIIE1 , cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1 , cytochrome P450-J , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , cytochrome P450, 2e1, ethanol inducible , cytochrome P450-ALC , P450-J , P450RLM6 , cytochrome P450 subfamily 2e1 (ethanol-inducible) , cytochrome P450, subfamily 2E, polypeptide 1 , cytochrome P450RLM6 , cytochrome P-450-J , cytochrome P450 CYP2E1

GENE ID SPEZIES
100066422 Equus caballus
554344 Felis catus
6345684 Pyrenophora tritici-repentis Pt-1C-BFP
100342572 Oryctolagus cuniculus
100727914 Cavia porcellus
101843716 Mesocricetus auratus
1571 Homo sapiens
415128 Canis lupus familiaris
13106 Mus musculus
25086 Rattus norvegicus
403216 Sus scrofa
282213 Bos taurus
100568285 Ovis aries
678688 Macaca mulatta
Ausgewählte Anbieter für anti-Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Antikörper
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