anti-Cytochrome C Oxidase Assembly Homolog 10 (Yeast) (COX10) Antikörper

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. Zusätzlich bieten wir Ihnen COX10 Proteine (2) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
COX10 70383 Q8CFY5
COX10 1352 Q12887
COX10 691853  
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Top anti-COX10 Antikörper auf antikoerper-online.de

Showing 10 out of 63 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-COX10 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Lung COX10 antibody - middle region  validated by WB using mouse mitochondria at 1:1000. 100 μL 2 bis 3 Tage
$319.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-COX10 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Spleen 100 μL 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert EIA, FACS, IHC (p), WB COX10 Antibody (C-term) flow cytometric analysis of CEM cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. COX10 antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the COX10 antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. 0.4 mL 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IP, WB Western blot analysis of COX10 expression in Hela (A), HEK293T (B), mouse kidney (C), mouse brain (D) whole cell lysates. 200 μL 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert ELISA, WB Western Blot (WB) analysis of Mouse Kidney Mouse Brain HeLa KB 293T lysis using COX10 antibody. Western Blot (WB) analysis of KB lysis using COX10 antibody. 100 μL Verfügbar
$363.46
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$581.17
Details
Fledermaus Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis of COX10 using HeLa whole cell lysates 100 μL 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis in CEM cell line lysates (35ug/lane). COX10 antibody immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. 400 μL 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL 2 bis 3 Tage
$446.88
Details

Weitere Antikörper gegen COX10 Interaktionspartner

Mouse (Murine) Cytochrome C Oxidase Assembly Homolog 10 (Yeast) (COX10) Interaktionspartner

  1. Loss of COX10 is associated with severe, early-onset Focal Segmental Glomerulosclerosis with innate immune activation and kidney failure.

  2. Mice lacking COX10 in skeletal muscle recapitulate the phenotype of progressive mitochondrial myopathies associated with cytochrome c oxidase deficiency.

  3. The levels of respiratory complex I were markedly reduced in COX10 knockout clones.

Human Cytochrome C Oxidase Assembly Homolog 10 (Yeast) (COX10) Interaktionspartner

  1. On the basis of its pivotal role in regulating cell death upon COX dysfunction, CerS6 might potentially represent a novel target for therapeutic intervention in mitochondrial diseases caused by COX dysfunction.

  2. ISCU and COX10 are target genes of miR-210 related to mitochondrial metabolism

  3. COX 15 mRNA was significantly more abundant in the cerebral tissue of Alzheimer's disease (AD) patients and COX10 and COX15 SNP were significantly less represented in the patient group, suggesting a possible protective role toward the risk for AD

  4. The expression of the AOX, well-tolerated by the cells, compensates for both the growth defect and the pronounced oxidant-sensitivity of COX-deficient human cells.

  5. Cytochrome c oxidase is decreased significantly in platelets and hippocampus in Alzheimer patients compared to controls.

  6. COX10 has a role in mitochondrial heme A biosynthesis

  7. This study report a cytochrome c oxidase (COX)-deficient patient, clinically affected with Leigh-like disease, with a homozygous mutation in the COX10 start codon.

  8. Geranylgeranyltransferase inhibitor-2147 (GGTI-2147), an inhibitor of this enzyme prenylation, elicited significant inhibition of glucose-stimulated insulin secretion from INS 832/13 islet cells.

Arabidopsis thaliana Cytochrome C Oxidase Assembly Homolog 10 (Yeast) (COX10) Interaktionspartner

  1. AtCOX10 was localized in mitochondria and was able to restore growth of a yeast Deltacox10 null mutant on non-fermentable carbon sources. Plants with T-DNA insertions in the coding region of both copies of AtCOX10 could not be recovered.

COX10 Antigen-Profil

Protein Überblick

Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes heme A:farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. This protein is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.

Genbezeichner und Symbole assoziert mit COX10

  • cytochrome c oxidase assembly protein 10 (Cox10) Antikörper
  • COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor (cox10) Antikörper
  • COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor L homeolog (cox10.L) Antikörper
  • COX10, heme A:farnesyltransferase cytochrome c oxidase assembly factor (COX10) Antikörper
  • cytochrome c oxidase 10 (COX10) Antikörper
  • protoheme IX farnesyltransferase, mitochondrial (LOC100732273) Antikörper
  • COX10 heme A:farnesyltransferase cytochrome c oxidase assembly factor (Cox10) Antikörper
  • 2410004F01Rik Antikörper
  • AU042636 Antikörper
  • Cox10 Antikörper
  • cytochrome c oxidase 10 Antikörper
  • F4I1.50 Antikörper
  • F4I1_50 Antikörper
  • im:7145568 Antikörper
  • im:7157205 Antikörper
  • wu:fb18a03 Antikörper

Bezeichner auf Proteinebene für COX10

COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase , heme O synthase , protoheme IX farnesyltransferase, mitochondrial , cytochrome c oxidase assembly protein , cytochrome c oxidase subunit X , heme A: farnesyltransferase , heme A:farnesyltransferase , cytochrome c oxidase assembly homolog 10

GENE ID SPEZIES
70383 Mus musculus
553384 Danio rerio
779326 Xenopus laevis
417329 Gallus gallus
1352 Homo sapiens
489515 Canis lupus familiaris
511440 Bos taurus
819059 Arabidopsis thaliana
100732273 Cavia porcellus
691853 Rattus norvegicus
100073118 Equus caballus
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