Cyclin K Proteine (CCNK)

The protein encoded by CCNK is a member of the transcription cyclin family. Zusätzlich bieten wir Ihnen Cyclin K Antikörper (58) und Cyclin K Kits (12) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CCNK 8812 O75909
CCNK 12454  
Ratte CCNK CCNK 500715  
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Showing 5 out of 5 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Baculovirus infected Insect Cells Human GST tag   50 μg Anmelden zum Anzeigen 10 bis 12 Tage

CCNK Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine)

Weitere Proteine zu Cyclin K (CCNK) Interaktionspartnern

Human Cyclin K (CCNK) Interaktionspartner

  1. Structures of CDK12 (zeige CRKRS Proteine)/CycK complexes solved in the presence of AMP (zeige APRT Proteine)-PNP (zeige NP Proteine).

  2. Data show that most mutations prevent formation of the cyclin-dependent kinase 12 (Cdk12 (zeige CRKRS Proteine))/cyclin K (CycK) complex, rendering the kinase inactive.

  3. Cyclin K is highly expressed in mammalian testes in a developmentally regulated manner.

  4. Cyclin K interacts with CDK12 and CDK13 but not CDK9 in cells, and is required to maintain self-renewal in ES cells.

  5. Cyclin (zeige PCNA Proteine) K1 is the primary cyclin (zeige PCNA Proteine) partner for CDK12/CrkRS (zeige CRKRS Proteine) and it is required for activation of CDK12/CrkRS (zeige CRKRS Proteine) to phosphorylate the C-terminal domain of RNA Pol II.

  6. Cyclin K inhibits HIV-1 gene expression and replication by interfering with cyclin-dependent kinase 9 (CDK9 (zeige CDK9 Proteine))-cyclin T1 (zeige CCNT1 Proteine) interaction in Nef-dependent manner.

  7. These results reveal an unexpectedly direct role for CDK9 (zeige CDK9 Proteine)-cyclin K in checkpoint pathways that maintain genome integrity in response to replication stress.

  8. Cyclin K-expressing multiple myeloma LP-1 (zeige RPLP1 Proteine) cells have lost their migration properties and display enhanced clonogenic capacities

  9. P-TEFb (zeige CCNT1 Proteine) containing cyclin K and Cdk9 (zeige CDK9 Proteine) can activate transcription via RNA.

  10. cyclin K may play a role in regulating the cell cycle or apoptosis

Mouse (Murine) Cyclin K (CCNK) Interaktionspartner

  1. that cyclin K may be a novel molecular link between germ cell development, cancer development and embryonic stem cell maintenance.

  2. Cyclin K-containing kinase complexes maintain self-renewal in murine embryonic stem cells.

Cyclin K (CCNK) Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the transcription cyclin family. These cyclins may regulate transcription through their association with and activation of cyclin-dependent kinases (CDK) that phosphorylate the C-terminal domain (CTD) of the large subunit of RNA polymerase II. This gene product may play a dual role in regulating CDK and RNA polymerase II activities.

Genbezeichner und Symbole assoziert mit Cyclin K Proteine (CCNK)

  • Cyclin K (CycK)
  • cyclin K (ccnk)
  • cyclin K L homeolog (ccnk.L)
  • cyclin-K (LOC5578158)
  • cyclin K (CCNK)
  • cyclin K (Ccnk)
  • cyclin-K pseudogene (LOC100345846)
  • AW123198 Protein
  • AW413594 Protein
  • CG15218 Protein
  • CPR4 Protein
  • CycK Protein
  • cyclin-K Protein
  • Dmel\\CG15218 Protein
  • fe49g08 Protein
  • MGC115029 Protein
  • MGC145994 Protein
  • si:dkey-60a16.2 Protein
  • wu:fe49g08 Protein
  • zgc:158372 Protein

Bezeichner auf Proteinebene für Cyclin K Proteine (CCNK)

CG15218-PA , CG15218-PB , CycK-PA , CycK-PB , CyclinK , cyclin K , cyclin k , cyclin-K

49816 Drosophila melanogaster
569432 Danio rerio
734423 Xenopus laevis
779776 Xenopus (Silurana) tropicalis
5578158 Aedes aegypti
100018485 Monodelphis domestica
8812 Homo sapiens
12454 Mus musculus
423446 Gallus gallus
612481 Canis lupus familiaris
100157799 Sus scrofa
530744 Bos taurus
500715 Rattus norvegicus
100345846 Oryctolagus cuniculus
101117113 Ovis aries
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